Apoptosis

Publication Date	January 2008
Publisher	RI Technologies
Product Type	Report
Pages	131
ISBN Number	not applicable
Product Code	RIT00009

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Summary

This market insight report gives an insight into Apoptosis Molecular Pathways - Caspase Activators and Inhibitors, Protease/Proteasome Inhibitors, Bcl-2 Modulators and p53 Modulators. The study also focuses on major diseases for which the treatment is based on apoptosis comprising Cancer, Neurodegenerative Diseases, Cardiovascular Diseases and other apoptosis based diseases including HIV Infection, Organ Transplant Rejection and MODS. The study provides global market analysis for apoptosis related therapeutic products by the above apoptosis molecular pathways and also by the disease areas. Estimates and projections for the total global apoptosis related therapeutic products market are given by geographic regions encompassing United States, Europe, Japan and Rest of World.

Business profiles of 41 major companies are discussed in the report. The report covers 256 companies that are engaged in apoptosis research, testing and supply of products and services. Major Contract Research Organizations and Universities serving apoptosis market are also covered in the Corporate Directory section of this report. Information related to product developments, partnerships, collaborations, and mergers and acquisitions is also included in the report. A total of 61 exhibits complement the text.

Content

I. Scope And Methodology
II. Report Synopsis
I. Foreword
- 1.
  - Apoptosis
  - Segmentation of Apoptosis
  - Exhibit 1: Segmentation of Global Apoptosis Related Products Market by Apoptosis Molecular Pathways (Caspases, Protease Inhibitors, Bcl-2 Modulators, p53 Modulators and Other) and Therapeutic Areas (Cancer, Neurodegenerative Diseases, Cardiovascular Diseases and Other)
- 2. Global Market Analysis
  - Exhibit 2: Apoptosis Related Products (2005-2011) - Global Market Analysis (Current & Future) in US$ Million (Graphical Representation Included)
  - Caspases
  - Exhibit 3: Caspase Activators and Inhibitors (2005-2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 4: Caspase Activators and Inhibitors (2005, 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World
  - Protease Inhibitors
  - Exhibit 5: Protease Inhibitors (2005-2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 6: Protease Inhibitors (2005, 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World (Graphical Representation Included)
  - Bcl-2 Modulators
  - The Role of Bcl-2 in Dis
  - Exhibit 7: Bcl-2 Modulators (2005-2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 8: Bcl-2 Modulators (2005, 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World (Graphical Representation Included)
  - p53 Modulators
  - Exhibit 9: p53 Modulators (2005-2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 10: p53 Modulators (2005 , 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World (Graphical Representation Included)
  - Other
  - Exhibit 11: Other Molecular Pathways of Apoptosis (2005-2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 12: Other Molecular Pathways of Apoptosis (2005, 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World (Graphical Representation Included)
  - Analysis of Apoptosis Related Products by Therapeutic Area Cancer
  - Role of Apoptosis Proteins and Genes in Cancer
  - Bcl-2 Modulators
  - IAPs
  - Global Market Analysis
  - Exhibit 13: Apoptosis Related Therapeutic Products for Cancer (2005-2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 14: Apoptosis Related Therapeutic Products for Cancer (2005, 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World (Graphical Representation Included) Global Market for Major Cancer Types
  - Exhibit 15: Major Cancer Types (2005 & 2006): Global Market for Major Cancer Types - Breast, Colorectal, Lung and Prostate in US$ Million(Graphical Representation Included) Global Cancer Demographics
  - Exhibit 16: Cancer Incidents (2006, 2010 & 2020): Estimates and Projections for Global Cancer Incidents in Million/Year with Mortality Percentage(Graphical Representation Included)
  - Neurodegenerative Diseas
  - Exhibit 17: Apoptosis Related Therapeutic Products for Neurodegenerative Diseases (2005- 2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 18: Apoptosis Related Therapeutic Products for Neurodegenerative Diseases (2005, 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World
  - Neurodegenerative Diseases Market
  - Exhibit 19: Global Neurodegenerative Diseases Market (2005, 2006 and 2007) in US$ Million(Graphical Representation Included)
  - Cardiovascular Diseases
  - Exhibit 20: Apoptosis Related Therapeutic Products for Cardiovascular Diseases (2005-2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 21: Apoptosis Related Therapeutic Products for Cardiovascular Diseases (2005, 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World
  - Other
  - Exhibit 22: Therapeutic Products for Other Apoptosis Based Diseases (2005-2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 23: Therapeutic Products for Other Apoptosis Based Diseases (2005, 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World
  - Exhibit 24: List of Major Global Companies
- 3. Regional Market Analysis
  - The United States
  - Exhibit 25: Apoptosis Related Products (2005-2011) - United States Market Analysis (Current & Future) in US$ Million (Graphical Representation Included)
  - A Glance at Major Companies in the United States
  - Europe
  - Exhibit 26: Apoptosis Related Products (2005-2011) - European Market Analysis (Current & Future) in US$ Million (Graphical Representation Included)
  - A Glance at Major Companies in Europe
  - Japan
  - Exhibit 27: Apoptosis Related Products (2005-2011) - Japanese Market Analysis (Current & Future) in US$ Million (Graphical Representation Included)
  - Takeda Pharmaceutical Co., Ltd. - A Major Market Player
  - Rest of World
  - Exhibit 28: Apoptosis Related Products (2005-2011) - Rest of World Market Analysis (Current & Future) in US$ Million (Graphical Representation Included)
  - A Glance at Major Companies in Rest of World Region
III. Product Research
- 1. Introduction
  - Apoptosis - The Major Form of Programmed Cell Death
  - Global Growth Trends - Apoptosis Related Therapeutic Products
  - Exhibit 29: Global Market for Apoptosis Related Therapeutic Products: Geographic Regions (United States, Japan and Europe) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - The Process of Apoptosis
  - Cell Death Due to Injury
  - Cell Death Due to Suicide
  - Reasons for Cell Suici
  - Cell surface Recept
  - Tumor Necrosis Factor Receptor Group Includes Death Receptors
  - Tumor Necrosis Factor Receptors and Ligands
  - Indication and Variation of Death Receptors
  - Medicine for Tumor 'Death' Receptors
  - Experiments and Combination of Medicines
  - Procedures for Apoptosis Identification
  - The ISEL technique
  - TUNEL technique
  - Methods for Understanding Apoptosis
  - DNA Fragmentation to Aid Apoptosis Measurement
  - Measurement of Variations in Apoptosis by Cdk2
  - Apoptotic Cell Clearance Measurement In Vitro
  - Exploring Apoptosis in Drosophila
  - Apoptosis Identification in Lymphoid cells
  - Identifying & Analyzing Apoptosis in Tissue Sections
  - Measurement of Variations in Intracellular Calcium Experienced During Apoptosis
  - Study of Apoptosis of Primary Sympathetic Neurons
  - Detection of Apoptosis Regulatory Genes
- 2. Apoptosis Molecular Pathways
  - Growth Trends - Global Apoptosis Related Therapeutic Products by Molecular Pathways
  - Exhibit 30: Global Market for Apoptosis Related Therapeutic Products: Apoptosis Molecular Therapeutics (Bcl-2 Modulators, p53 Modulators, Caspases and Protease Inhibitors) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - Key Molecular Pathways of
  - Caspases
  - Growth Trends - Global Market for Caspase Activators and Inhibitors
  - Exhibit 31: Global Market for Caspase Activators and Inhibitors: Geographic Regions (United States, Japan and Europe) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - Types of Caspase Proteins
  - Initiator Caspases
  - Effector Caspases
  - The Caspase Flow
  - Function of Caspases in Apoptosis, Development and Cytokine Maturation
  - Card Domains
  - Granzymes
  - Cytochrome C OR CYT C
  - Protease Inhibitors
  - Growth Trends - Global Market for Protease Inhibitors
  - Exhibit 32: Global Market for Protease Inhibitors: Geographic Regions (Japan, Europe and United States) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - Bcl-2 Modulators
  - Growth Trends - Global Market for Bcl-2 Modulators
  - Exhibit 33: Global Market for Bcl-2 Modulators: Geographic Regions (United States, Japan and Europe) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - Structure of Bcl-2 Family
  - The Role of Bcl-2 in Diseases
  - Biochemical Properties of Bcl-2 Proteins
  - Cytoplasmic Proteins
  - Interleukin-2 (IL-2) - BAX
  - p53 Modulators
  - Role of p53 in Apoptosis
  - Mitochondrial Membrane Permeablility Control
  - Growth Trends - Global Market for p53 Modulators
  - Exhibit 34: Global Market for p53 Modulators: Geographic Regions (United States, Japan and Europe) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - Other Apoptosis Molecular
  - Inhibitors of Apoptosis Prote
  - Identification of IAP Gene Family Proteins
  - TRAIL
  - MLK Inhibitor
  - Factor 5A
  - Protein Kinase Pathway
  - Chemotherapeutic Role of Telcyta in Various Cancers
  - Nicotinic Acetylcholine Receptor Agonist
  - HSP27
- 3. Disease Areas Connected with Apoptosis
  - Growth Trends - Global Market for Apoptosis Therapeutic Areas
  - Exhibit 35: Global Market for Apoptosis Therapeutic Products: Major Apoptosis Related Therapeutic Areas (Neurodegenerative Diseases, Cardiovascular Diseases and Cancer) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - Cancer
  - Role of Apoptosis in Cancer Treatment
  - Major Companies in Global Cancer Market
  - Exhibit 36: Global Market for Cancer Therapeutic Products (2005 & 2006): Percentage Breakdown of Market Share for Top 10 Companies - Roche, Sanfo-Aventis, Amgen, Astra-Zeneca, Novartis, Johnson & Johnson, Bristol-Myer Squibb, Schering-Plough, Pfizer, Eily-Lilly (Graphical Representation Included)
  - Growth Trends - Global Market for Apoptosis Related Therapeutic Products for Cancer
  - Exhibit 37: Global Market for Apoptosis Related Therapeutic Products for Cancer: Geographic Regions (Japan, United States and Europe) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - Neurodegenerative Disease
  - Growth Trends - Global Market for Apoptosis Related Therapeutic Products for
  - Neurodegenerative Disease
  - Exhibit 38: Global Market for Apoptosis Related Therapeutic Products for Neurodegenerative Disease: Geographic Regions (United States, Japan and Europe) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - Alzheimer€s
  - Importance of Apoptosis in Alzheimer€s Disease
  - Familial Alzheimer's Disease and Role Of Mutant APP
  - Parkinson€s
  - Function of Apoptosis in PD and Symptoms of Neuronal Degradation
  - Apoptosis in Parkinson's Disease and Nigral Neuronal Death
  - Potential Markers of Apoptosis in Parkinson's Disease
  - Rheumatoid Arthritis
  - Role of Apoptosis in Rheumatoid Arthritis Synovium
  - Multiple Sclerosis
  - The Diagnosis of MS
  - Functioning of Oligodendrocytes Apoptosis in MS and EAE
  - Mediators of OLG Death in MS
  - Fas-Fas Ligand Syste85
  - Cardiovascular Diseases - Role of Cell Apoptosis
  - Growth Trends - Global Market for Apoptosis Related Therapeutic Products for Cardiovascular Disease
  - Exhibit 39: Global Market for Apoptosis Related Therapeutic Products for Cardiovascular Disease: Geographic Regions (United States, Japan and Europe) Ranked by Projected CAGR for 2005 through 2011 (Graphical Representation Included)
  - Other Apoptosis Based Dis
  - Organ Transplant Rejection
  - Types of Organ Rejection
  - Hyperacute Rejection
  - Acute Rejection
  - Chronic Rejection
  - Treating Rejection
  - HIV Infection
  - Sepsis and Multiple Organ Dysfunction Syndrome
  - Requirement of Logical Strategies
  - Sepsis Controlled by Apoptosis
- 4. Apoptosis Therapeutics
  - Technologies Involved in Drug Making Process for Apoptosis Based Treatment
  - Target Discovery and Va
  - Structural Biology
  - Drug Candidate Identificat91
  - Antisense
  - Types of Antisense
  - The nbl Antisense
  - Antisense CK2
  - Np73 Antisense
  - Np73 Function in SH-SY5Y Neuroblastoma Cells
  - Small Molecule Mimetics
  - Drug Discovery
  - Combinatorial Chemistry
  - Drug Discovery using Combinatorial Chemistry
  - High Throughput Screening
  - Analysis of Apoptosis Based Drugs - Listed by Molecular Pathways
  - Caspases
  - Executioner Caspases
  - CASPASE-8
  - Caspase-3
  - IDN-6556
  - Application of IDN-6556 for Human Liver Preservation Injury
  - MX1122
  - MX1013
  - Protease Inhibitors
  - >VELCADE (BORTEZOMIB)
  - >Bcl-2 Modulators
  - >Genase
  - Genasense in Combination with Chemotherapy
  - Genasense: Positive effects On Bladder Tumor
  - >The Genasense App98
  - G3139 therapy€s antitumor activity effects in vitro and vivo
  - G3139 with rituximab
  - Genasense - Cytoxan Therapy
  - Genasense - In Combination with Taxetir
  - Genasense - Ideal for Lymphoma and in Melanoma Tumor
  - Genasense - In Combination with Chemotherapy
  - Genasense - Positive Effects on Bladder Tumor
  - HA14-1
  - p53 Modulators
  - SCH58500
  - INGN 241
  - INGN 241 in combination with Introgen
  - Administration of INGN 241 with Herceptin
  - INGN 251
  - ONYX-015
  - Apoptosis Related Products in Developments
  - The Combination of Apoptosis with Anti-Angiogenesis Yields Better Results
  - Personalized Cancer Therapy with Caspase-3
  - Sunesis Pharmaceuticals Conducts Stage 2 Clinical Trial of SNS-595
  - The SNS-595 Technol 103
  - Epicept Commences Phase 1 Clinical Trials of EPC 2407
  - Introgen Bags Patent for INGN 401
  - Cellgate Begins Phase II Clinical Test of CGC-11047 for Prostate Cancer Treatment
  - Aegera Repeats Clinical Research for AEG35156
  - Exhibit 40: Some of the Apoptosis Related Products in Development
  - Major Apoptosis Products
  - RT2 Profiler PCR Arrays-SuperArray Bioscience Corporation
  - InnoCyte Flow Cytometric Cytochrome c Release Kit-EMD Biosciences, Inc.
  - PhosphoDetectMEK1 (pSer 218/222) ELISA Kit-EMD Biosciences, Inc.
  - InnoCyte ECM Cell Adhesion Assay, Galectin-1/Galectin-3- EMD Biosciences, Inc.
  - MSA07 Apoptosis Detection Kit- MitoScience, Inc.
  - Guava EasyCyteTM Mini- Guava Technologies, Inc
  - Multi-parameter Apoptosis 1 HitKit HCS Reagent Kit- Cellomics, Inc.
  - GeneBlocker pGB siRNA expression vectors- Biovision, Inc.
IV. Market Dynamics
- 1. Market Overview
  - Global Market Analysis
  - Exhibit 41: Apoptosis Related Products (2005-2011) - Global Market Analysis (Current & Future) by Geographic Region for United States, Europe, Japan and Rest of World in US$ Million (Graphical Representation Included)
  - Exhibit 42: Apoptosis Related Products (2005, 2008 and 2011) - Percentage Breakdown of Global Market Value by Geographic Region for United States, Europe, Japan and Rest of World (Graphical Representation Included)
- 2. Major Companies in Apoptosis Market
  - A.G. Scientific, Inc. (USA)
  - Abbott Laboratories (USA)
  - Aegera Therapeutics, Inc. (Canada)
  - Aida Pharmaceuticals, Inc. (China)
  - Alexion Pharmaceuticals, Inc. (USA)
  - Alfacell Corporation (USA)
  - Amgen, Inc. (USA)
  - Antisoma plc (UK)
  - Applied Molecular Evolution (USA)
  - Ariad Pharmaceuticals, Inc. (USA)
  - ArQule, Inc (USA)
  - AVI BioPharma Inc. (USA)
  - BD Biosciences (USA)
  - Cyclacel Pharmaceuticals, Inc. (USA)
  - Dendreon Corporation (USA)
  - D-Pharm Ltd. (Israel)
  - EntreMed, Inc. (USA)
  - EpiCept Corporation (USA)
  - F.Hoffmann-La Roche Ltd. (Switzerland)
  - Genta, Inc. (USA)
  - Genzyme Corporation (USA)
  - Incyte Corporation (USA)
  - Introgen Therapeutics, Inc. (USA)
  - Invitrogen, Inc. (USA)
  - ISIS Pharmaceuticals, Inc. (USA)
  - MGI Pharma, Inc. (USA)
  - Millennium Pharmaceuticals Inc. (USA)
  - Novartis AG (Switzerland
  - Novogen Limited (Austra
  - Onyx Pharmaceuticals, Inc. (USA)
  - OSI Pharmaceuticals, Inc. (USA)
  - Pfizer, Inc. (USA)
  - Pharmacyclics, Inc. (USA)
  - Schering-Plough Corporation (USA)
  - Sigma-Aldrich Corporation (USA)
  - Takeda Pharmaceutical Co., Ltd. (Japan)
  - Titan Pharmaceuticals, Inc. (USA)
  - Vasogen, Inc. (Canada)
  - Vertex Pharmaceuticals, Inc. (USA)
  - Xenova Group Limited (UK)
  - Zentaris GmbH (German
- 3. Recent Activities in Apoptosis Market
  - MMRC Joins Hands with Keryx
  - EpiCepts EPC2407 Best for Lymphomas and Advanced Stage in Cancer
  - Gemin X Undertakes Further Research on GX15-070
  - Genentech Purchases Stake in Tanox
  - XOMA Ties-up with Takeda
  - TorreyPines Therapeutics Merges with Axonyx
  - Aida Acquires Qiaer Bio-Technology
  - TopoTarget and CuraGen Initiates PXD101 and Azacitidine Clinical Trials
  - Enzon to Develop a Series of RNA Antagonists
  - Millipore Acquires Serologicals Corp.
  - Takeda Enters into Agreement with Galaxy Biotech
  - Human Genome Sciences Commences Phase 2 clinical Trial of HGS-ETR1
  - Stressgen Assumes New Corporate Identity
  - Sigma-Aldrich Launches PanoramaTM
  - Bioniche Receives Fast Track Designation from US FDA
  - CST Signs Pact with AstraZeneca
  - Takeda Enters into Partnership with Arius
  - Pharminox Enters into Agreement with Cancer Research Technology
  - Geron Commences Clinical Trial of GRN163L
  - VGX Pharmaceuticals Signs R&D Agreement with Dowpharma
  - EpiCept Enters into Merger Agreement with Maxim
  - Targacept Signs Partnership and Licensing Agreement with AstraZeneca
  - Apoxis Enters into Deal with Astellas Pharma
  - PIramed Enters into Alliances with Genentech
  - Invitrogen Takes Over BioSource International
  - MedImmune Signs Agreement with VasGene
  - Nanocure Adopts New Corporate Identity
  - Pfizer Inc., Acquires Idun Pharmaceuticals
  - AXXORA Merges with APOTECH
  - ExonHit Therapeutics Receives New Patent on Microarray Product
  - Invitrogen Takes Over Zymed Laboratories
  - B-Bridge Enters into Deal with RZPD
  - Genta Acquires C-Myb Antisense Drug
  - Antisoma plc Presents Data on TTAs
  - QIAGEN Unveils Comprehensive Human siRNA Library Sets
- 4. Regional Market Analysis
  - A. The United States
    - Market Analysis
    - Exhibit 43: Apoptosis Related Products (2005-2011) - United States Market Analysis (Current & Future) in US$ Million (Graphical Representation Included)
    - Analysis by Apoptosis Molecular Pathways
    - Exhibit 44: Apoptosis Related Products (2005-2011) - United States Market Analysis (Current & Future) by Apoptosis Molecular Pathways for Caspases, Protease Inhibitors, Bcl-2 Modulators, p53 Modulators and Other in US$ Million (Graphical Representation Included)
    - Exhibit 45: Angiogenesis Therapeutic Products (2005, 2008 and 2011) - Percentage Breakdown of United States Market Value by Apoptosis Molecular Pathways for Caspases, Protease Inhibitors, Bcl-2 Modulators, p53 Modulators and Other
    - Analysis by Therapeutic Area
    - Exhibit 46: Apoptosis Related Products (2005-2011) - United States Market Analysis (Current & Future) by Therapeutic Area for Cancer, Neurodegenerative, Cardiovascular and Other in US$ Million (Graphical Representation Included)
    - Exhibit 47: Apoptosis Related Products (2005, 2008 and 2011) - Percentage Breakdown of United States Market Value by Therapeutic Area for Cancer, Neurodegenerative, Cardiovascular and Other
    - Exhibit 48: List of Major Companies in the United States
  - B. Europe
    - Market Analysis
    - Exhibit 49: Apoptosis Related Products (2005-2011) - European Market Analysis (Current & Future) in US$ Million (Graphical Representation Included)
    - Analysis by Geographic Region
    - Exhibit 50: Apoptosis Related Products (2005-2011) - European Market Analysis (Current & Future) by Geographic Region for Germany, United Kingdom, France and Rest of Europe in US$ Million (Graphical Representation Included)
    - Exhibit 51: Apoptosis Related Products (2005, 2008 and 2011) - Percen tage Breakdown of European Market Value by Geographic Region for Germany, United Kingdom, France and Rest of Europe Analysis by Apoptosis Molecular Pathways
    - Exhibit 52: Apoptosis Related Products (2005-2011) - European Market Analysis (Current & Future) by Apoptosis Molecular Pathways for Caspases, Protease Inhibitors, Bcl-2 Modulators, p53 Modulators and Other in US$ Million (Graphical Representation Included)
    - Exhibit 53: Angiogenesis Therapeutic Products (2005, 2008 and 2011) - Percentage Breakdown of European Market Value by Apoptosis Molecular Pathways for Caspases, Protease Inhibitors, Bcl-2 Modulators, p53 Modulators and Other
    - Analysis by Therapeutic Area
    - Exhibit 54: Apoptosis Related Products (2005-2011) - European Market Analysis (Current & Future) by Therapeutic Area for Cancer, Neurodegenerative, Cardiovascular and Other in US$ Million (Graphical Representation Included)
    - Exhibit 55: Apoptosis Related Products (2005, 2008 and 2011) - Percentage Breakdown of European Market Value by Therapeutic Area for Cancer, Neurodegenerative, Cardiovascular and Other
    - Exhibit 56: List of Major Companies in the Europe
  - C. Japan
    - Market Analysis
    - Exhibit 57: Apoptosis Related Products (2005-2011) - Japanese Market Analysis (Current & Future) in US$ Million (Graphical Representation Included)
    - Analysis by Apoptosis Molecular Pathways
    - Exhibit 58: Apoptosis Related Products (2005-2011) - Japanese Market Analysis (Current & Future) by Apoptosis Molecular Pathways for Caspases, Protease Inhibitors, Bcl-2 Modulators, p53 Modulators and Other in US$ Million (Graphical Representation Included)
    - Exhibit 59: Angiogenesis Therapeutic Products (2005, 2008 and 2011) - Percentage Breakdown of Japanese Market Value by Apoptosis Molecular Pathways for Caspases, Protease Inhibitors, Bcl-2 Modulators, p53 Modulators and Other (Graphical Representation Included)
    - Analysis by Therapeutic Area
    - Exhibit 60: Apoptosis Related Products (2005-2011) - Japanese Market Analysis (Current & Future) by Therapeutic Area for Cancer, Neurodegenerative, Cardiovascular and Other in US$ Million (Graphical Representation Included)
    - Exhibit 61: Apoptosis Related Products (2005, 2008 and 2011) - Percentage Breakdown of Japanese Market Value by Therapeutic Area for Cancer, Neurodegenerative, Cardiovascular and Other (Graphical Representation Included)
    - Exhibit 62: List of Major Companies in Japan
  - D. Rest of World
    - Market Analysis
    - Exhibit 63: Apoptosis Related Products (2005-2011) - Rest of World Market Analysis (Current & Future) in US$ Million (Graphical Representation Included)
    - Analysis by Apoptosis Molecular Pathways
    - Exhibit 64: Apoptosis Related Products (2005-2011) - Rest of World Market Analysis (Current & Future) by Apoptosis Molecular Pathways for Caspases, Protease Inhibitors, Bcl-2 Modulators, p53 Modulators and Other in US$ Million (Graphical Representation Included)
    - Exhibit 65: Angiogenesis Therapeutic Products (2005, 2008 and 2011) - Percentage Breakdown of Rest of World Market Value by Apoptosis Molecular Pathways for Caspases, Protease Inhibitors, Bcl-2 Modulators, p53 Modulators and Other
    - Analysis by Therapeutic Area
    - Exhibit 66: Apoptosis Related Products (2005-2011) - Rest of World Market Analysis (Current & Future) by Therapeutic Area for Cancer, Neurodegenerative, Cardiovascular and Other in US$ Million (Graphical Representation Included)
    - Exhibit 67: Apoptosis Related Products (2005, 2008 and 2011) - Percentage Breakdown of Rest of World Market Value by Therapeutic Area for Cancer, Neurodegenerative, Cardiovascular and Other
    - Exhibit 68: List of Major Companies in Rest of World
- 5. Apoptosis Molecular Pathways - The Market Outlook
V. Corporate Directory