The Spanish Cancer Diagnostics Market

Publication Date	September 2009
Publisher	Venture Planning Grp.
Product Type	Report
Pages	565
ISBN Number	not applicable
Product Code	VEP00251

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Summary

This report presents a comprehensive analysis of the Spanish cancer diagnostics market, including:

Major issues pertaining to the Spanish laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next ten years.
Mortality statistics and scientific views on the etiology of major types of cancer, e.g., lung, colorectal, breast, prostatic, pancreatic, leukemia, lymphoma, gastrointestinal, bladder, liver, ovarian, testicular, oral, skin and others.
Ten-year test volume and sales forecasts for 40 cancer diagnostic procedures performed in Spanish hospitals, commercial laboratories and ambulatory care centers
Placements and installed base of automated and semiautomated analyzers used for cancer testing.
Current instrumentation technologies and feature comparison of leading analyzers.
Sales and market shares of leading suppliers.
Emerging diagnostic technologies and their potential market applications.
Product development opportunities.
Profiles of current and emerging suppliers, including their sales, market shares, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.
Business opportunities and strategic recommendations for suppliers.

Content

INTRODUCTION
WORLDWIDE MARKET AND TECHNOLOGY OVERVIEW
- A. CANCER STATISTICS AND ETIOLOGY
- 1. Bladder
- 2. BreastIntroduction
Worldwide Market and Technology Overview
- A. Cancer Statistics and Etiology
- 1. Bladder
- 2. Breast
- 3. Cervical
- 4. Colon and Rectum
- 5. Endometrial
- 6. Esophagus
- 7. Head and Neck
- 8. Leukemia
- 9. Lung
- 10. Lymphoma
- 11. Oral
- 12. Ovarian
- 13. Prostate
- 14. Renal Cell Carcinoma
- 15. Skin
- 16. Stomach
- 17. Uterine
- B. Major Current And Emerging Cancer Diagnostic Tests
- 1. Introduction
- 2. Tumor Marker Classification
- 3. ACTH
- 4. Alpha-Fetoprotein (AFP)
- 5. Beta-2 Microglobulin
- 6. CA 15-3/27.29
- 7. CA 19-9
- 8. CA-125
- 9. Calcitonin
- 10. Carcinoembrionic Antigen (CEA)
- 11. Estrogen and Progesterone Receptors
- 12. Ferritin
- 13. Gastrin
- 14. Human Chorionic Gonadotropin (HCG)
- 15. Insulin
- 16. Lymphocytes CD4/CD8
- 17. NSE
- 18. Occult Blood
- 19. PAP Smear/HPV
- 20. Prostatic Acid Phosphatase (PAP)
- 21. Prostate-Specific Antigen (PSA)
- 22. Squamous Cell Carcinoma Antigen (SCC)
- 23. TdT
- 24. Thyroglobulin
- 25. Tissue Polypeptide Antigen (TPA)
- 26. Biochemical Tumor Markers
  - ADA
  - B-Protein
  - PNP
  - 5'-Nucleotidase
- 27. Oncogenes
  - Abl/abl-bcr
  - AIB1
  - APC
  - BTA 26
  - BCL-2
  - BCR-ABL
  - B-raf
  - BRCA
  - CD44
  - CDK
  - C-abl
  - C-fos
  - C-myb
  - C-myc
  - CYCD1
  - CYP-17
  - DPC
  - E-myc
  - Erb-B
  - HER-2/neu
  - HPC1
  - HSTF
  - L-myc
  - MET
  - MSH
  - NEU
  - N-myc
  - N-telopeptide
  - PCA3
  - PIK3CA
  - PTI-1
  - P10
  - P40
  - P51
  - P53
  - Ras
  - Reg
  - RET
  - sFas
  - Sis
  - Src
- 28. Polypeptide Growth Factors
  - Basic Fibroblast Growth Factor
  - Beta-TGF
  - Cachectin (TNT)
  - Calmodulin
  - ECFR
  - Nerve Growth Factor (NGF)
  - Epidermal Growth Factor (EGF)
  - Ornithine Decarboxylase
  - Transferrin
  - Transforming Growth Factor-Alpha
- 29. Ectopic Hormones
- 30. Colony Stimulating Factors
- 31. Lymphokines
  - Alpha-Interferon
  - B Cell Growth Factors
  - B Cell Growth Factor (BCGF)
  - Gamma-Interferon
  - Interleukin-1 (IL-1)
  - Macrophage Activating Factor
- 32. Immunohistochemical Stains
- 33. Emerging Tumor Markers
  - N-Acetylglucosamine
  - Actin
  - Alpha-Actin
  - Angiogenin
  - Angiostatin
  - Antineuronal Antibodies
  - 7B2
  - B72.3
  - B-Protein
  - Bax
  - BCD-F9
  - BLCA-4
  - Blood Group Antigens A,B,H
  - BTA
  - CA 50
  - CA 72-4/TAG-72
  - CA 195
  - CA-242
  - CA-549
  - Cadherin
  - CAM 26
  - CAR-3
  - CD105
  - Cathepsin-D
  - Chromogranin A and B
  - Cluster 1 Antigen
  - Cluster-5/5A Antigen
  - COX Antigen
  - CTA
  - CU18
  - Cyclin
  - DR-70
  - DU-PAN-2
  - Endometrial Bleeding Associated Factor
  - Endostatin
  - Epithelial Membrane Antigen
  - FDP
  - Feulgen Hydrolysis
  - Fibronectin
  - FSH
  - (1->3)-L-fucosyltransferase
  - Gastrin-Releasing Peptide (GRP)
  - GDCFP-15
  - Glucagon
  - Glycoamines
  - H23
  - HAAH
  - hk3
  - HPA
  - HSP27
  - Human Carcinoma Antigen
  - ICAM
  - Intermediate Filaments
  - Cytokeratins/CK18/Cyfra 21-1
  - Desmin
  - Gliofibrillary Acid Protein
  - Neurofilaments
  - Vimentin
  - KA 93
  - Kallikrein
  - Kinases
  - KP16D3
  - LAI
  - Leukocyte Common Antigen
  - Lewis Antigens
  - Lysophosphatidic Acid (LPA)
  - Ma 695/Ma 552
  - MABDF3
  - MAG
  - ME1
  - Minactivin
  - MN/CA9
  - MSA
  - Mucin Cancer Antigen (MCA)
  - Multiple Tumor Suppressor 1
  - Myosin
  - NEA-130
  - NMP22
  - Nucleolar
  - OA-519
  - Opiod Peptides
  - P-glycoprotein
  - Pancreatic Oncofetal Antigen (POA)
  - Parathyrcoid Hormone
  - Placental Lactogen
  - PR92
  - Proliferative Index, Ki-67
  - Px
  - RB Inactivation/Deletion
  - Ret
  - S-100 Protein
  - SCCL 175
  - Selectin
  - Serotonin
  - Sialic Acid
  - Sialyl SSEA-1/SLX
  - SN10
  - Somatostatin
  - TA-90
  - TABA
  - Tachykinin
  - TAG 12
  - TPS
  - Troponin
  - Tubulin
  - VCAM
  - VEGF
  - Villen
  - White Blood Cell Markers
- C. Instrumentation Review And
Market Needs
- Abbott Architect
- Abbott AxSYM
- Abbott IMx
- Amersham Amerlite
- Bayer ACS: 180
- Bayer ADVIA Centaur
- Bayer Immuno 1
- Beckman Coulter Access
- bioMerieux Vidas Series
- Biotrol System 7000
- Dade Behring Dimension
- DPC Immulite
- DiaSorin ETI-Max
- Ortho-Clinical Diagnostics Vitros
- Olympus PK Series
- Roche Elecsys
- Roche Modular
- Tosoh AIA Series
D. Current and Emerging Technologies
- 1. Monoclonal and Polyclonal Antibodies
- 2. Immunoassays
- a. Technological Principle
- b. Radioimmunoassay (RIA)
- c. Enzyme Immunoassays (EIA)
  - Overview
  - ELISA
  - Immunofiltration
  - Particle-Membrane Capture Immunoassay
  - Enzyme Amplification
- d. Fluorescent Immunoassays
- e. Luminescence
  - Chemiluminescence
  - Bioluminescence
- 3. Molecular Diagnostics
- a. Technology Overview
- b. Amplification Methods
  - PCR
  - DAP-PCR
  - Immuno-PCR
  - QC-PCR
  - CAR
  - DNA
  - HPA
  - LCR
  - NASBA
  - QBR
  - SDA
  - 3 SR, and others
- 4. Biochips/Microarrays
- 5. Chromosome Analysis
- a. Chronic Myelogenous Leukemia (CML)
- b. Acute Myeloid Leukemia (AML)
- c. Acute Lymphoblastic Leukemia (ALL)
- d. Malignant Lymphomas
Lymphoid Malignancies
- e. Chronic Lymphocytic Leukemia (CLL)
- f. Solid Cancers
- g. Chromosomal Translocation and Oncogenes
- 6. Microcomputers and Automation
- 7. Artificial Intelligence
- 8. Flow Cytometry
- 9. Biosensors
- E. Competing/Complementing Technologies
- 1. CT
- 2. MRI
- 3. NMR
- 4. PET
- 5.Photonics Spectroscopy
- F. Business Environment
- 1. Worldwide Market Structure
- 2. Worldwide Market Size and Growth
- G. Personal Testing
Spain
- A. Executive Summary
- B. Business Environment
- C. Market Structure
- D. Market Size, Growth and Major Suppliers
Major Product Development Opportunities
- A. Reagent Kits and Test Systems/Panels
- B. Instrumentation
- C. Computers, Software and Automation
- D. Auxiliary Products
Design Criteria for Decentralized Testing Products
- Alternative Market Penetration Strategies
- A. Internal Development
- B. Collaborative Arrangements
- C. University Contracts
- D. Distribution Strategies
- 1. Marketing Approaches
- 2. Product Complexity
- 3. Customer Preference
- 4. Established Suppliers
- 5. Emerging Suppliers
- 6. Major Types of Distributors
- 7. Market Segmentation Factor
Potential Market Entry Barriers and Risks
- A. Market Maturity
- B. Cost Containment
- C. Competition
- D. Technological Edge and Limitations
- E. Patent Protection
- F. Regulatory Constraints
- G. Decentralized Testing Market Challenges
Competitive Profiles
- Abbott
- AdnaGen
- Agensys
- Altana
- Ambrilia Biopharma
- AMDL
- BD
- Beckman Coulter
- Biofield
- Biomedical Diagnostics
- bioMerieux
- Bio-Rad
- Biotrol/B. Braun
- CeMines
- Cepheid
- CIS/BIO
- Cliniqa
- Correlogic Systems
- Cytyc
- Daiichi
- DakoCytomation
- diaDexus
- DiagnoCure
- Diagnostic Systems
- Dianon
- DiaSorin
- Digene
- Eiken
- Enterix
- Enzo Biochem
- Epigenomics
- Exact Sciences
- Fujirebio
- Gen-Probe
- Gene Logic
- Green Cross
- Grifols-Quest
- Guided Therapeutics
- Ibex Technologies
- Immunicon
- Ipsogen
- Kyowa Medex
- Matritech
- Molecular Diagnostics
- Myriad Genetics
- Nippon Flour Mills
- OncoLab
- Ortho-Clinical Diagnostics
- Panacea Pharmaceuticals
- Polartechnics
- Polymedco
- PreMD
- Quest Diagnostics Nichols Institute
- Roche Diagnostics
- Scantibodies
- Siemens
- Targeted Diagnostics
- Tosoh
- Trylon
- Wako Chemicals
- Worldwide Medical
- Zila
Appendixes
- Appendix I: Major Companies Developing or Marketing Cancer Diagnostic Reagents and Instruments
- Appendix II: Major Universities and Research Centers Developing Cancer Diagnostic Technology and Applications
- Appendix III: Assumed Currency Exchange Rates
List of Tables
- Tumor Marker Classification
- Major Companies Developing or Marketing ACTH Tests
- Major Companies Developing or Marketing AFP Tests
- Major Companies Developing or Marketing Beta-2 Microglobulin Tests
- Major Companies Developing or Marketing CA 15-3/27.29 Tests
- Major Companies Developing or Marketing CA 19-9 Tests
- Major Companies Developing or Marketing CA 125 Tests
- Major Companies Developing or Marketing Calcitonin Tests
- Major Companies Developing or Marketing CEA Tests
- Major Companies Developing or Marketing Estrogen Receptor Tests
- Major Companies Developing or Marketing Progesterone Receptor Tests
- Major Companies Developing or Marketing Ferritin Tests
- Major Companies Developing or Marketing Gastrin Tests
- Major Companies Developing or Marketing HCG Tests
- Major Companies Developing or Marketing Insulin Tests
- Major Companies Developing or Marketing NSE Tests
- Major Companies Developing or Marketing Occult Blood Tests
- Major Companies Developing or Marketing PAP Smear/HPV Tests
- Major Companies Developing or Marketing PAP Tests
- Major Companies Developing or Marketing PSA Tests
- Major Companies Developing or Marketing Lymphocyte Subclassification Tests
- Biochemical Markers Potential Applications In Cancer Diagnosis
- Oncogenes Potential Applications In Cancer Diagnosis
- Major Companies Developing or Marketing Oncogene Tests
- Growth Factors Potential Applications In Cancer Diagnosis
- Colony Stimulating Factors Potential Applications in Cancer Diagnosis
- Lymphokines Potential Applications In Cancer Diagnosis
- Immunohistochemical Stains Potential Applications in Cancer Diagnosis
- Executive Summary Table: Spain, Total Tumor Marker Test Volume and Sales Forecast by Market Segment
- Spain, Estimated Cancer Death Rates Per 100,000 Population
- Spain, Laboratories Performing Tumor Marker Tests by Market Segment
- Spain, Hospital Laboratories Performing Tumor Marker Tests by Bed Size
- Commercial/Private Laboratories Performing Tumor Marker Tests By Annual Test Volume
- Spain, Total Tumor Marker Testing Volume Forecast by Market Segment
- Spain, All Market Segments Major Tumor Marker Test Volume Forecast
- Spain, Hospital Laboratories Major Tumor Marker Test Volume Forecast by Test
- Spain, Commercial/Private Laboratories Major Tumor Marker Test Volume Forecast
- Spain, Total Tumor Marker Sales Forecast by Market Segment
- Spain, All Market Segments Major Tumor Marker Sales Forecast by Test
- Spain, Hospital Laboratories Major Tumor Marker Sales Forecast by Test
- Spain, Commercial/Private Laboratories Major Tumor Marker Sales Forecast by Test
- Spain, ACTH Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, AFP Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Beta-2 Microglobulin Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, CA 15-3/27.29 Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, CA 19-9 Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, CA-125 Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Calcitonin Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Cathepsin Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, CEA Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Chromogranin Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Colon-Specific Antigen Test Volume And Diagnostics Sales Forecast by Market Segment
- Spain, Cytokeratins Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Estrogen Receptor Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Ferritin Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Gastrin Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, HCG Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Insulin Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Interferons Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Interleukins Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Lymphocyte Subtyping Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, NSE Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Nucleolar Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Occult Blood Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Oncogenes Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Pancreatic Oncofetal Antigen Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, PAP Smear Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Parathyroid Hormone Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Progesterone Receptor Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, PAP Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, PSA Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, S-100 Protein Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Serotonin Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Sialic Acid Test Volume and Diagnostics Sales Forecast by Market Segment Spain, Squamous Cell Carcinoma Antigen Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, TDT Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Thymidine Kinase Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Thyroglobulin Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, TPA, Test Volume and Diagnostics Sales Forecast by Market Segment
- Spain, Total Tumor Marker Sales by Major Suppliers
- Spain, AFP Testing Market Diagnostics Sales by Major Supplier
- Spain, CA 15-3/27.29 Testing Market Diagnostics Sales by Major Supplier
- Spain, CA 19-9 Testing Market Diagnostics Sales by Major Supplier
- Spain, CA 125 Testing Market Diagnostics Sales by Major Supplier
- Spain, Calcitonin Testing Market Diagnostics Sales by Major Supplier
- Spain, CEA Testing Market Diagnostics Sales by Major Supplier
- Spain, NSE Testing Market Diagnostics Sales by Major Supplier
- Spain, PAP Testing Market Diagnostics Sales by Major Supplier
- Spain, PSA Testing Market Diagnostics Sales by Major Supplier
- Spain, Tumor Marker Testing Instrumentation, Major Systems Estimated Placements and Installed Base By Supplier and Model