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High Throughput Screening (HTS)

High Throughput Screening (HTS)

This report analyzes the worldwide markets for High Throughput Screening (HTS) in US$ Million. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through 2017. A six-year historic analysis is also provided for these markets. The report profiles 103 companies including many key and niche players such as Agilent Technologies Inc., Aurora Biomed Inc., Axxam SpA, Beckman Coulter, Inc., BioFocus DPI Ltd., Bio-Rad Laboratories, Inc., BMG LABTECH GmbH, Caliper Life Sciences, Inc., Corning Inc., DiscoveRx Corporation, EVOTEC BioSystems, ForteBio, Inc., Genedata AG, IntelliCyt Corporation, Life Technologies Corporation, Luminex Corporation, Molecular Devices Inc., PerkinElmer Inc., Roche Applied Sciences, Sigma-Aldrich Corporation, and Tecan Group Ltd. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain.

  • I.INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
  • Study Reliability and Reporting Limitations
  • Disclaimers
  • Data Interpretation & Reporting Level
  • Quantitative Techniques & Analytics
  • Product Definitions and Scope of Study
  • II. EXECUTIVE SUMMARY
  • 1.INDUSTRY OVERVIEW
    • A Prelude
    • Market Scenario
    • How Far Has HTS Been Successful - A Case for and Against HTS
    • Market Share Findings
    • Table 1: World Liquid Handling Market (2010): Percentage Market Share Breakdown of Leading Players (includes corresponding Graph/Chart)
    • Table 2: World Robotics Market (2010): Percentage Market Share Breakdown of Leading Players (includes corresponding Graph/Chart)
    • Table 3: World Microplate Readers Market (2010): Percentage Market Share Breakdown of Leading Players (includes corresponding Graph/Chart)
  • 2.MARKET TRENDS & ISSUES
    • HTS Adapts to Varied Lead Discovery Needs
    • Compound Library and Target Selection Equally Important as Screening
    • Cell-based Assays Represent the Primary Drug Discovery Tool in HTS Labs
    • Smaller Companies and Academia Can Now Afford HTS
    • Innovation in Screening Guarantees Success for Drug Discovery Programs
    • HTS Advancements Promise a Bright Future for Stem Cell Research
    • HTS in the Discovery of Drug for Alzheimer's disease
    • Need for Stringent QA System to Keep Failures at Bay
    • HTS Used in Identification of Kinase Inhibitors
  • 3.HTS TECHNOLOGY OVERVIEW
    • What Drives HTS Labs towards New Technologies
    • Major HTS Technologies
    • Miniaturization
    • HTS Miniaturization - Technology Developments
    • IVC - A Miniaturized, Powerful HTS Technology
    • Target Selection
    • Label-free Technologies
    • High-Content Screening (HCS)
    • Innovations in Cell Culture
    • Compound Libraries Expansion
    • HTS - A Historical Perspective
  • 4.PRODUCT OVERVIEW
    • High Throughput Research (HTR)
    • High Throughput - An Advanced Materials Research Approach
    • Pharmaceutical Industry Leads the Way
    • High Throughput Improves R&D Efficiency
    • High Throughput Screening (HTS)
    • The Equipment
    • The Process
    • HTS Robotics Supports Miniaturization
    • HTS and uHTS
    • Functional and Non-Functional - Two Types of High Throughput Assays
    • Setting up HTS Facilities - An Expensive Affair
    • Important Components of HTS
    • Few popular Chemical Libraries Used in Chemical Biology and Drug Discovery
    • Table 4: Screening Throughput of Plates (includes corresponding Graph/Chart)
    • Distinctions Between Bench Top and HTS Assays
  • 5.HTS AND THE PHARMA INDUSTRY
    • Impact of HTS on the Pharmaceutical Industry
    • The Underlying Technology and Market Factors
    • High Costs Involved with Sophistication - A Matter of Concern
    • The HTS Business in Pharma Industry
    • What Lies Ahead for HTS
    • Hit and Lead Generation Strategies
    • Different Stages in Hit and Lead Generation
    • From 'Hit' to 'Lead' in HTS - A Complex Endeavor
  • 6.DRUG DISCOVERY - AN OVERVIEW
    • Drug Discovery - Definition
    • Drug Discovery Process
    • Drug Discovery Technologies
  • 7.COMPUTER AIDED DRUG DISCOVERY (CADD)
    • The Evolution of Computer Aided Drug Discovery (CADD) Processes
    • CADD
    • High Throughput Screening
    • Virtual Screening
    • Cloud Computing
  • 8.PRODUCT INTRODUCTIONS/ INNOVATIONS
    • Tox21 Launches Novel Robotic High Speed Screening System
    • Life Technologies Introduces TaqMan OpenArray MicroRNA Panels
    • Zyleris Introduces Screening Service for Drug Development
    • Genosphere Introduces PepLib™ Custom Peptide Library Synthesis
    • PerkinElmer Launches Lance Ultra cAMP Detection Kit for Profiling GPCRs
    • PerkinElmer Introduces Epigenetics Detection Reagents for HTS of New Drug Candidates
    • Agilent and BIOCIUS Introduce RF360 High Resolution System
    • High Throughput Genomics and Luminex Introduce qBead Assay
    • IntelliCyt Launches HTFCTM Screening System
    • Luminex Corporation Launches FLEXMAP 3D, a High-Throughput System
    • ForteBio Introduces Advanced Instruments for Life Science Research Industry
    • BioTrove Introduces RapidFire® 300 System for HTS of ADME Assays
    • Sigma-Aldrich Launches PrecisioTM Kinases for High Througput Profiling
    • Genedata Launches Genedata Screener 7.0 for HCS and HTS Analysis
    • Roche Diagnostics Introduces RTCA HT Instrument
    • Axxam and CyBio Introduce An Advanced Screening Station
    • BMG LABTECH Unveils PHERAstar FS Reader for HTS Applications
    • PharmaDiagnostics Unveils SoPRano CA1 Assay Kit
    • SwitchGear Genomics Introduces High Throughput Screening Tools
    • PerkinElmer Launches Upgraded MicroBeta®2 Microplate Counter Platform
    • Intellicyt Launches Hypercyt Based Application, Flowtox Screening
  • 9.RECENT INDUSTRY ACTIVITY
    • Danaher Acquires Beckman Coulter
    • Pall Acquires ForteBio
    • Agilent Technologies Takes Over BIOCIUS Life Sciences
    • EVOTEC BioSystems Takes Over Kinaxo Biotech
    • Beckman Coulter and Vitrology Ink Biologics Testing Partnership Agreement
    • Sigma Life Sciences and King's College Co-develop Target Identification Technology
    • Lundbeck and Compound Focus Ink Compound Management Agreement
    • Ligand to Divest Combinatorial Library and Certain Technologies to Venenum
    • DiscoveRx Corp Acquires Kinase Screening Service Division of Ambit Biosciences
    • Omeros Takes Over GPCR Assay Technology from Patabios
    • TGS Collaborates with CarnaBio for Providing Drug Discovery Services
    • AstraZeneca and MRC Technology Team Up for Drug Discovery, Share Compound Libraries
    • Evotec and Biotech Partner for Small Molecule Modulator Identification
    • ForteBio and Tecan Team Up to Provide Automated Label-Free Assays
    • Protein Attachment and Blue Sky Biotech Ink Licensing Agreement
    • BioAtla and Halozyme Team Up
    • Jubilant Biosys and DiscoveRx Enter into an Co-marketing Agreement
    • Plasticell Inks Partnership Agreement with Sigma-Aldrich
    • Redpoint Bio Receives US Patent for its HTS Assay for TRPm5 Ion Channel
    • Corning Takes Over Axygen BioScience
    • ChanTest Takes over Applied Cell Sciences
    • Nexus Biosystems Takes over Aurora Biotechnologies
    • PerkinElmer Acquires Assets of GE Healthcare
    • Cellectis and Laboratoires Servier Ink Licensing Agreement
    • BioFocus to Integrate TET Technology in HTS Services
    • BioFocus DPI Upgrades High-Throughput Screening Library
    • Ono Pharmaceutical and Evotec Extend Research Collaboration
    • Randox Labs and Seegene Enter into Agreement
    • BioFocus DPI and Cellectricon Enter into Collaboration
    • Evotec and DiscoveRx Ink Agreement to Support HTS Services
    • Corning Announces a Major Milestone in Label- Free High Throughput Screening
  • 10.FOCUS ON SELECT GLOBAL PLAYERS
    • Agilent Technologies Inc. (US)
    • Aurora Biomed Inc. (Canada)
    • Axxam SpA (Italy)
    • Beckman Coulter, Inc (US)
    • BioFocus DPI Ltd (UK)
    • Bio-Rad Laboratories, Inc. (US)
    • BMG LABTECH GmbH (Germany)
    • Caliper Life Sciences, Inc (US)
    • Corning Inc (US)
    • DiscoveRx Corporation (US)
    • EVOTEC BioSystems (Germany)
    • ForteBio (US)
    • Genedata AG (Switzerland)
    • IntelliCyt Corporation (US)
    • Life Technologies Corporation (US)
    • Luminex Corporation (US)
    • Molecular Devices Inc. (US)
    • PerkinElmer Inc (US)
    • Roche Applied Sciences (Germany)
    • Sigma-Aldrich Corporation (US)
    • Tecan Group Ltd. (Switzerland)
  • 11.GLOBAL MARKET PERSPECTIVE
    • Table 5: World Recent Past, Current & Future Analysis for High Throughput Screening by Geographic Region - US, Canada, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
    • Table 6: World Historic Review for High Throughput Screening by Geographic Region - US, Canada, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
    • Table 7: World 15-Year Perspective for High Throughput Screening by Geographic Region - Percentage Breakdown of Dollar Revenues for US, Japan, Europe, and Rest of World Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart)
    • III. MARKET
  • 1.THE UNITED STATES
    • A. Market Analysis
    • Factors Driving Growth in the US HTS Market
    • Government Providing a Helping Hand
    • Product Introductions
    • Strategic Corporate Developments
    • Key Players
    • B. Market Analytics
    • Table 8: US Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
    • Table 9: US Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
  • 2.CANADA
    • A. Market Analysis
    • Key Players
    • B. Market Analytics
    • Table 10: Canadian Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
    • Table 11: Canadian Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
  • 3.JAPAN
    • A. Market Analysis
    • Strategic Corporate Development
    • B. Market Analytics
    • Table 12: Japanese Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
    • Table 13: Japanese Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
  • 4.EUROPE
    • A. Market Analysis
    • Market Shifts Towards Maturity - Technological Innovations Come to the Rescue
    • Product Introductions
    • Strategic Corporate Developments
    • Key Players
    • B. Market Analytics
    • Table 14: European Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
    • Table 15: European Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
  • 5.REST OF WORLD
    • A. Market Analysis
    • Regional Overview
    • HTS Gaining Ground in APAC
    • China
    • China Emerges as the Major Outsourcer for Drug Discovery
    • Few Problem Areas Exist...
    • What Outsourcers Need to Look Forward to...
    • Life Sciences Market in China Continues to Thrive Despite Recession
    • B. Market Analytics
    • Table 16: Rest of World Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)
    • Table 17: Rest of World Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)
    • IV. COMPETITIVE LANDSCAPE
    • Total Companies Profiled: 103 (including Divisions/Subsidiaries - 107)
    • Region/CountryPlayers
    • The United States
    • Canada
    • Japan
    • Europe
    • France
    • Germany
    • The United Kingdom
    • Italy
    • Rest of Europe
    • Asia-Pacific (Excluding Japan)
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