Anti Infectives, Vol II: Antibacterials

Publication Date	April 2007
Publisher	Kalorama Information
Product Type	Report
Pages	276
ISBN Number	not applicable
Product Code	KAL00015

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Summary

Antibacterial drugs have turned bacterial infections into treatable ailments rather than the life-threatening conditions they once were. But the effectiveness of many antibiotics is being reduced as more and more types of bacteria become resistant to them. Because of antibiotic resitance and other changing dynamics, knowledge of issues and trends is necessary to operate the antibacterials market.Kalorama's Anti-Infectives, Vol. II: Antibacterials provides extensive detail on the anti-bacterial market, including the following critical trends:

Drug resistance and Interactions

Antibiotic Abuse
Antibiotic Cycling
Addressing Market Trends
Antibiotic Use in Agriculture
Antibiotic Education
Children and Bacterial Resistance
The Elderly and Bacterial Resistance
Compromised Individuals and Bacterial Resistance
Screening Hospital Patients
Side Effects of Antibiotics
Partnerships and Alliances
Environment and Drug Resistance
Methicillin Resistant Staphylococcus Aureus

In this, the second volume of Kalorama Information's Anti-Infective Markets series, the antibacterial drug market is broken down into seven general categories based on drug class:

cephalosporins
macrolides
penicillins
quinolones
sulfonamides
tetracyclines
other misc.
antibiotics

There is a significant trend shift occuring in the antibacterials market since Kalorama Information's last edition in 2005. Anti-Infectives Vol. II: Antibacterials covers that shift in detail. For each marketplace segment, Market Size, Growth and Share are provided, and revenue is forecasted to 2011 are provided. Current products are discussed and new pipeline products are assessed. In total, over 100 Tables and Figures provide accessible data on this growing market, a depth of coverage unsurpassed by any competitive study.The following companies are profiled as part of this report:

Abbott Laboratories
AstraZeneca
Bayer Schering Pharma
Cubist Pharmaceuticals
Daiichi Sankyo
GlaxoSmithKline
Johnson & Johnson Group
King Pharmaceuticals
Merck & Company, Inc.
Pfizer, Inc.
Roche
Sanofi-Aventis
Wyeth

Content

Executive Summary
Introduction
- Scope and Methodology
- Size and Growth of the Market
- Issues and Trends Affecting Market
- Leading Competitors
Introduction The World Market For Anti-Infectives Volume 2:
- Antibacterial Drugs
- Introduction to pathogens
- Classification of Antibacterial Organisms
- Antimicrobial Spectrum
- Bacterial Resistance
- Principles of Anti-infective Therapy
- Infecting Organism
- Antibiotic Sensitivity Testing
- Site of Infection
- Host Defenses and Organ Function
- Antibiotic Pharmacokinetics
- Monitoring Therapy
Combination Therapy And Prophylactic Use
- Demographics and Statistics
Issues And Trends Affecting The Antibacterial Drug Market
- introduction
- Drug Resistance and Interactions
- Antibiotic Abuse
- Antibiotic Cycling
- addressing market trends
- Antibiotic use in Agriculture
- Antibiotic Education
- Children and Bacterial resistance
- The Elderly and Bacterial Resistance
- Compromised Individuals and Bacterial Resistance
- Screening Hospitalized patients
- Side Effects of Antibiotics
- Partnerships and Alliances
- Environment and Drug Resistance
- Methicillin-resistant Staphylococcus Aureus (MRSA)
Cephalosporin Antibiotics
- Overview
- Description of Products
- First Generation Cephalosporins
- Cephalexin (Keflex, Advancis Pharmaceuticals)
- Cefazolin (Ancef, GlaxoSmithKline; Cefamezin, Astellas)
- Cefadroxil (Duricef, Bristol-Myers Squibb/Warner Chilcot)
- Second Generation Cephalosporins
- Cefuroxime (Ceftin, GlaxoSmithKline)
- Cefoxitin (Mefoxin, Merck)
- Third Generation Cephalosporins
- Cefotaximen (Claforan offered by Sanofi-Aventis)
- Cefoperazone (Cefobid, Pfizer)
- Ceftibutin (Cedax, Shionogi)
- Ceftizoxime (Cefizox, Astellas)
- Ceftriaxone (Rocephin, Roche)
- Ceftazidime (Fortaz, GlaxoSmithKline)
- Cefixime (Suprax, Wyeth/Lupin Pharmaceuticals)
- Cefpodoxime (Vantin, Pfizer)
- Fourth Generation Cephalosporins
Cefepime (Maxipime, Bristol-Myers Squibb)
- Generic Drug Impact and Availability
- Research and Development
- Market Size and Growth
- Competitive Analysis
Macrolide Antibiotics
- Overview
- Description of Products
- Azithromycin (Zithromax, Pfizer; Zmax, Pfizer)
- Clarithromycin (Biaxin, Abbott Laboratories)
- Erythromycin (Erythrocin, Abbott Laboratories; EryPed, Abbott Laboratories)
Telithromycin (Ketek, Sanofi-Aventis)
- Generic Drug Impact and Availability
- Research and Development
- Market Size and Growth
- Competitive Analysis
Penicillin Antibiotics
- Overview
- Natural Penicillins
- Penicillinase-Resistant Penicillins
- Broad -Spectrum Penicillins
- Extended-Spectrum Penicillins
Description Of Products
- Natural Penicillins
- Penicillin G (Bicillin, King Pharmaceuticals; Pfizerpen, Pfizer)
- Penicillinase-resistant Penicillins
- Cloxacillin (Cloxapen, GlaxoSmithKline)
- Oxacillin (Bactocill, GlaxoSmithKline)
- Broad-spectrum Penicillins
- Amoxicillin (Augmentin, GlaxoSmithKline; Amoxil,GlaxoSmithKline)
- Ampicillin (Unasyn, Pfizer)
- Extended-spectrum Penicillins
- Carbenicillin (Geocillin, Pfizer)
- Piperacillin (Pipracil, Wyeth; Zosyn, Wyeth)
Ticarcillin (Timentin, Glaxosmithkline)
- Generic Drug Impact and Availability
- Research and Development
- Market Size and Growth
- Competitive Analysis
Quinolone Antibiotics
- Overview
- Description of Products
- Ciprofloxacin (Cipro, Bayer; Proquin XR, Depomed)
- Gemifloxacin (Factive, LG Chem Ltd. and Oscient Pharmaceuticals)
- Lomefloxacin (Maxaquin, Unimed)
- Nalidixic (NegGram, Sanofi-Aventis)
- Norfloxacin (Noroxin, Merck)
- Ofloxacin (Floxin, Ortho-McNeil)
- Moxifloxicin (Avelox, Bayer; Vigamox, Alcon)
- Levofloxacin (Levaquin, Ortho-McNeil; Tavanic, Sanofi-Aventis; Cravit, Daiichi Sankyo; Quixin, Santen)
- Gatifloxacin (Zymar, Allergan/Kyorin)
Trovafloxacin (Trovan, Pfizer)
- Generic Drug Impact and Availability
- Research and Development
- Market Size and Growth
- Competitive Analysis
Sulfonamide Antibiotics
- Overview
- Description of Products
- Sulfisoxazole (Gantrisin Pediatric, Roche)
- Oxytetracycline/Sulfamethizole/Phenazopyridine (Urobiotic, Pfizer)
- Erythromycin ethylsuccinate and Sulfisoxazole acetyl (Pediazole, Ross)
Dapsone (Aczone Gel, Qlt USA-Tolmar Inc.)
- Research and Development
- Market Size and Growth
- Competitive Analysis
Tetracycline Antibiotics
- Overview
- Description of Products
- Generic Drug Impact and Availability
- Research and Development
- Market Size and Growth
- Competitive Analysis
Other Miscellaneous Antibiotics
- Overview
- Description of Products
- Aminoglycosides
- Amikacin Sulfate (Amikin, Bristol-Myers Squibb)
- Kanamycin Sulfate (Kantrex, Bristol-Myers Squibb)
- Neomycin Sulfate (Neo-fradin, X Gen Pharms)
- Streptomycin Sulfate (Streptomycin, Pfizer)
- Lincomycin
- Clindamycin (Cleocin, Pfizer; Clindesse, KV Pharmaceutical Company; Evoclin, Connetics Corp.; Ziana Gel, Medicis/Dow)
- Chloramphenicol
- Chloramphenicol (Chloromycetin,Pfizer)
- Glycopeptide
- Vancomycin (Vancocin, Viropharma)
- Monobactams
- Aztreonam (Azactam, Bristol-Myers Squibb)
- Carbapenems
- Imipenem/cilastatin (Primaxin, Merck)
- Meropenem (Merrem, AstraZeneca)
- Metronidazole
- Metronidazole (Flagyl, Pfizer; Pylera, Axcan; Metrogel-Vaginal, 3M Pharmaceuticals; MetroGel, Galderma)
- Antituberculars
- Rifampicin (Rifater, Sanofi-Aventis)
- Capreomycin (Capastat sulfate, Eli Lilly & Co.)
- Ethionamide (Trecator SC, Wyeth)
- Aminosalicylic acid granules (Paser Granules, Jacobus Pharmaceutical)
- Cycloserine (Seromycin, Eli Lilly & Co.)
- Antileprotics
- Dapsone (Dapsone, Jacobus)
- Oxazolidinones
- Linezolid (Zyvox, Pfizer)
- Ketolides
- Telithromycin (Ketek, Sanofi-Aventis)
- Lipopeptides
- Daptomycin (Cubicin, Cubist Pharmaceutical)
- Glycyclines
Tigecycline (Tygacil, Wyeth) Generic Drug Impact And Availability
- Research and Development
- Market Size and Growth
- Competitive Analysis
Corporate Profiles
- Introduction
- Abbott Laboratories
- AstraZeneca plc
- Bayer Schering Pharma AG
- Cubist Pharmaceuticals, Inc
- Daiichi Sankyo Co., Ltd.
- GlaxoSmithKline
- Johnson & Johnson Group
- King Pharmaceuticals, Inc.
- Merck & Company, Inc.
- Pfizer, Inc.
- Roche
- Sanofi-Aventis
- Wyeth
- Company Names and Addresses