Induced Pluripotent Stem Cells: Global Markets

Induced Pluripotent Stem Cells: Global Markets

  • June 2017
  • 139 pages
  • BCC Research
Report ID: 2212008
• The global market for induced pluripotent stem cells (iPSCs) reached $2.1 billion in 2016. The market should reach $3.6 billion in 2021, increasing at a compound annual growth rate (CAGR) of 11.6% from 2016 through 2021.
• The U.S. market for iPSCs reached over $1.0 billion in 2016. The market should reach $1.8 billion in 2021, increasing at a CAGR of 11.3% from 2016 through 2021.
• Asia-Pacific market for iPSCs reached $449 million in 2016. The market should reach $854 million in 2021, increasing at a CAGR of 12.3% from 2016 through 2021.

Chapter 1: Introduction


Study Goals and Objectives
The aim of this report is to provide detailed market and industry analyses to help readers quantify and qualify the global market for induced pluripotent stem cells (iPSCs). Important trends in the field and market segments are identified, and market sizes and sales forecasts by segmented markets are provided through 2021. This report focuses on the market side rather than the technical side. The detailed market segmentation, market shares, major drivers, trend analysis and forecasts for the entire iPSCs market are analyzed.


Reasons for Doing This Study
Detailed market and industry analysis for the iPSCs market is needed. As a breakthrough technology recognized by the Nobel Prize in Physiology or Medicine 2012, iPSCs technology may bring a revolutionary change to modern medicine. Great opportunities always exist with high risks, but the detailed analysis and forecasts of the iPSC market can provide useful information for all management levels to help make strategic decisions in related areas. iPSC-related products are forming an emerging market despite the fact that iPSC clinical applications are still at their early stage. The potential scope of the iPSC market is becoming clear, and it is appropriate to review the emerging market, see the current size and share of each segment, evaluate the market trends and look to its future.


Intended Audience
This report is designed to satisfy the information needs of various individuals involved in the biological research, pharmaceutical and regenerative medicine marketplaces, including senior management corporate executives seeking to base their strategic decisions on the best available information on market forces and trends. It is also aimed at managers and executives in marketing, research, planning and sales departments who need readable, comprehensive and up-to-date background material on the marketplaces associated with the induced pluripotent stem cells with which they are operating. This report was prepared as a study of the global market for induced pluripotent stem cells. Information is presented with a specific focus on the various market segments, including those based on product type, product function, application, geography and technological method. The detailed segmentation is to provide a deep profile of the global iPSCs market, upon which the market forecasts are made.

This study will be of significant interest to academic institutions, hospitals, biotech and pharmaceutical companies, biopharmaceutical researchers, marketing executives from pharmaceutical and biotech companies, contract research organizations, biologists, chemists, physicians, pharmaceutical directors, product managers and representatives, and all manner of institutional directors from either public or private entities. It will also be of interest to investment bankers in the biotechnology and pharmaceutical sectors, insurance executives and life sciences product marketing managers.


Scope of Report
This study is focused on the market side of iPSCs rather than its technical side. Different market segments for this emerging market are covered. For example, application-based market segments include academic research, drug development and toxicity testing, and regenerative medicine; product function-based market segments include molecular and cellular engineering, cellular reprogramming, cell culture, cell differentiation and cell analysis; iPSC-derived cell-type-based market segments include cardiomyocytes, hepatocytes, neurons, endothelia cells and other cell types; geography-based market segments include the U.S., Europe, Asia-Pacific and Rest of World. Research and market trends are also analyzed by studying the funding, patent publications and research publications in the field.


Methodology
Both primary and secondary research methodologies were used to prepare this study. Primary research includes interviews with leading individuals in stem cell companies and industry associations. Primary sources of published data include company annual reports, SEC filings, and government and industry publications. Secondary sources consist of literature searches, industry journals and other commercial publications. Data for market estimates and forecasts are pooled from a range of sources that were critically assessed by BCC Research.


Information Sources
Information sources included marketing strategists, industry executives, academic experts, government agencies and regulatory bodies, and surveys of scientists in both academic and industrial areas. Company annual reports and Securities and Exchange Commission (SEC) filings, journal articles, newsletters, expert blogs and data from related institutions were also reviewed.


Geographic Breakdown
In this report, the geographic regions considered for market analysis include, and only include:
United States
• California
• Massachusetts
• New York
• Wisconsin
• Other States

Europe
Asia-Pacific
Rest of World

Chapter 1: Introduction .. 1
Study Goals and Objectives 1
Reasons for Doing This Study 1
Intended Audience . 1
Scope of Report 2
Methodology . 2
Information Sources .. 2
Geographic Breakdown 2
Analyst's Credentials . 4
Related BCC Research Reports. 4
Chapter 2: Summary and Highlights .. 6
Key Drivers for Market Growth 6
Chapter 3: Overview .. 10
Introduction 10
History and Current State 11
Evolution of Induced Pluripotent Stem Cell Research .. 12
Induced Pluripotent Stem Cell Advantages and Disadvantages .. 12
Advantages . 12
Disadvantages .. 12
Technology Overview . 13
Induced Pluripotent Stem Cell Generation 14
Induced Pluripotent Stem Cell Differentiation . 17
Chapter 4: Induced Pluripotent Stem Cell Applications 21
Academic Research . 21
Pharmaco-Toxicological Screening . 21
Drug Discovery and Development .. 23
Disease Modeling . 23
Tissue Engineering .. 24
Cell Therapy 25
Chapter 5: Induced Pluripotent Stem Cell Market Segmentation and Forecast 27
Induced Pluripotent Stem Cell Market Overview 27
Application-Based Market Overview . 31
U.S. Induced Pluripotent Stem Cell Product Market . 33
Induced Pluripotent Stem Cell-Derived Tissue Cell Market 34
Induced Pluripotent Stem Cell and Derivative Cell Market 36
Major Suppliers and Manufacturers of Induced Pluripotent Stem Cell Products .. 36
Induced Pluripotent Stem Cell-Derived Cell Markets by Application .. 44
Induced Pluripotent Stem Cell Market by Product Function . 45
Global Market 46
Regional Markets . 47
Research Market vs. Clinical Market .. 49
Application-Based Markets for Induced Pluripotent Stem Cell-Derived Cells .. 50
Market for Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells . 50
Market for Human Hepatocytes Derived from Induced Pluripotent Stem Cells 56
Market for Human Endothelia Cells Derived from Induced Pluripotent Stem Cells . 61
Regional Markets . 62
Market for Human Neural Cells Derived from Induced Pluripotent Stem Cells . 66
Regional Markets . 67
Induced Pluripotent Stem Cells and Their Derived Cells Market by Species . 70
Global Market 70
Regional Markets . 71
Induced Pluripotent Stem Cell Culture Markets .. 73
Chapter 6: Induced Pluripotent Stem Cell Research Application Market . 76
Induced Pluripotent Stem Cell Research Product Types . 76
Major Players . 81
Major Commercial Entities . 81
Major Non-Commercial Organizations . 82
Market Shares and Projections . 84
Chapter 7: Drug Discovery and Development Market 86
Product Types 86
Major Players . 86
Market Shares and Projections . 86
Chapter 8: Induced Pluripotent Stem Cell Contract Service Market 90
Induced Pluripotent Stem Cell Contract Service Types 90
Major Players . 90
Market Shares and Projections . 91
Chapter 9: Induced Pluripotent Stem Cell Clinical Application Market .. 94
Product Types 94
Regulations . 94
Market Projection 95
Chapter 10: Research Market Trend Analysis . 99
Grant Analysis 99
Patent Analysis 102
Scientific Publication Analysis . 114
Driving Forces.. 115
Chapter 11: Clinical Application Market Trend Analysis . 118
Clinical Trials 118
Driving Forces.. 119
Limiting Factors .. 119
Technologies 119
Regulations .. 120
Market Acceptance . 120
Clinical Efficiency .. 121
Chapter 12: Company Profiles 123
Chapter 13: Conclusions 144
About BCC Research .. 146
About BCC Research. 147
BCC Membership .. 147
BCC Custom Research . 147

List of Tables
Summary Table: Global Induced Pluripotent Stem Cell Market, by Region, Through 2021 ($ Millions) 8
Table 1 U.S. Induced Pluripotent Stem Cell Product Market, by State, Through 2021 ($ Millions) .. 28
Table 2 Global Market for Methods for Generating Induced Pluripotent Stem Cells (Integrated and Non-
Integrated), Through 2021 ($ Millions) . 29
Table 3 Global Market for Methods for Generating Induced Pluripotent Stem Cells, Through 2021
($ Millions) .. 30
Table 4 Global Market for Induced Pluripotent Stem Cell Products, by Application, Through 2021
($ Millions) .. 32
Table 5 U.S. Induced Pluripotent Stem Cell Product Market, by Application, Through 2021 ($ Millions) . 33
Table 6 Global Market for Induced Pluripotent Stem Cell-Derived Tissue Cells, by Type, Through 2021
($ Millions) .. 35
Table 7 Global Market for Induced Pluripotent Stem Cell Derived Cells, by Species, Through 2021
($ Millions) .. 36
Table 8 Major Commercial Induced Pluripotent Stem Cell Product Suppliers, March 31, 2017 . 37
Table 9 Major Commercial Induced Pluripotent Stem Cell Product Manufacturers, March 31, 2017 . 40
Table 10 Global Market for Induced Pluripotent Stem Cell-Derived Cells, by Application, Through 2021
($ Millions) .. 44
Table 11 Global Market for Induced Pluripotent Stem Cell-Related Products, by Product Function,
Through 2021 ($ Millions) 46
Table 12 U.S. Market for Induced Pluripotent Stem Cell-Related Products, by Product Function, Through
2021 ($ Millions) .. 48
Table 13 Global Markets for Induced Pluripotent Stem Cells, by Research and Clinical Use, Through 2021
($ Millions) .. 49
Table 14 Global Market for Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes, by
Application, Through 2021 ($ Millions). 51
Table 15 U.S. Market for Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes, by Application,
Through 2021 ($ Millions) 53
Table 16 European Market for Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes, by
Application, Through 2021 ($ Millions). 54
Table 17 Asia-Pacific Market for Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes, by
Application, Through 2021 ($ Millions). 55
Table 18 Global Market for Induced Pluripotent Stem Cell-Derived Human Hepatocytes, by Application,
Through 2021 ($ Millions) 57
Table 19 U.S. Market for Induced Pluripotent Stem Cell-Derived Human Hepatocytes, by Application,
Through 2021 ($ Millions) 58
Table 20 European Market for Induced Pluripotent Stem Cell-Derived Human Hepatocytes, by
Application, Through 2021 ($ Millions). 59
Table 21 Asia-Pacific Market for Induced Pluripotent Stem Cell-Derived Human Hepatocytes, by
Application, Through 2021 ($ Millions). 60
Table 22 Global Market for Induced Pluripotent Stem Cell-Derived Human Endothelia Cells, by
Application, Through 2021 ($ Millions). 62
Table 23 U.S. Market for Induced Pluripotent Stem Cell-Derived Human Endothelia Cells, by Application,
Through 2021 ($ Millions) 63
Table 24 European Market for Induced Pluripotent Stem Cell-Derived Human Endothelia Cells, by
Application, Through2021 ($ Millions) . 64
Table 25 Asia-Pacific Market for Induced Pluripotent Stem Cell-Derived Human Endothelia Cells, by
Application, Through 2021 ($ Millions). 65
Table 26 Global Market for Induced Pluripotent Stem Cell-Derived Human Neural Cells, by Application,
Through 2021 ($ Millions) 66
Table 27 U.S. Market for Induced Pluripotent Stem Cell-Derived Human Neural Cells, by Application,
Through 2021 ($ Millions) 67
Table 28 European Market for Induced Pluripotent Stem Cell-Derived Human Neural Cells, by
Application, Through 2021 ($ Millions). 68
Table 29 Asia-Pacific Market for Induced Pluripotent Stem Cell-Derived Human Neural Cells, by
Application, Through 2021 ($ Millions). 69
Table 30 Global Market for Induced Pluripotent Stem Cells and Derivative Cells, by Species, Through
2021 ($ Millions) .. 71
Table 31 U.S. Market for Induced Pluripotent Stem Cells and Derivative Cells, by Species, Through 2021
($ Millions) .. 72
Table 32 European Market for Induced Pluripotent Stem Cells and Derivative Cells, by Species, Through
2021 ($ Millions) .. 72
Table 33 Asia-Pacific Market for Induced Pluripotent Stem Cells and Derivative Cells, by Species, Through
2021 ($ Millions) .. 73
Table 34 Global Market for Cell Culture Products for Induced Pluripotent Stem Cells and Derived Cells, by
Region, Through 2021 ($ Millions) .. 74
Table 35 Global Market for Induced Pluripotent Stem Cell-Related Products, by Function, Through 2021
($ Millions) .. 77
Table 36 U.S. Market for Induced Pluripotent Stem Cell-Related Products, by Function, Through 2021
($ Millions) .. 78
Table 37 Global Market for Induced Pluripotent Stem Cell-Derived Cell Products for Research, by Cell
Type, Through 2021 ($ Millions) .. 79
Table 38 Global Market for Induced Pluripotent Stem Cell Research, by Region, Through 2021
($ Millions) .. 80
Table 39 Major University and Institute Induced Pluripotent Stem Cell Core Facilities, by Location .. 82
Table 40 Global Market for Induced Pluripotent Stem Cell-Derived Cell Products for Drug Development
and Toxicity Testing, by Cell Type, Through2021 ($ Millions) .. 87
Table 41 Global Market for Induced Pluripotent Stem Cell Drug Development and Toxicity Testing,
by Region, Through 2021 ($ Millions) 88
Table 42 Major Companies Providing Induced Pluripotent Stem Cell Contract Services, 2016 .. 90
Table 43 Global Market for Induced Pluripotent Stem Cell Contract Services, by Region, Through 2021
($ Millions) .. 92
Table 44 Global Market for Induced Pluripotent Stem Cell Products for Regenerative Medicine, by Cell
Type, Through 2021 ($ Millions) .. 95
Table 45 Induced Pluripotent Stem Cell Clinical Global Markets (Including Patient-Specific Induced
Pluripotent Stem Cell Banking), by Region, Through 2021 ($ Millions) 96
Table 46 Major Governmental Induced Pluripotent Stem Cell Research Funding, by Region, 2006-2016
($ Millions/%) . 99
Table 47 National Institutes of Health Induced Pluripotent Stem Cell Research Funding, FY 2006-2016
(Number of Grants/$ Millions) .. 100
Table 48 California Institute of Regenerative Medicine Induced Pluripotent Stem Cell Funding, Through
January 2017 (Number/$Millions) 101
Table 49 Induced Pluripotent Stem Cell Patents Issued, by the U.S. Patent and Trademark Office, 2011 to
December 2016 .. 102
Table 50 U.S. Patent and Trademark Office-Issued Patents, by Region, 2011 to December 2016
(Number/%) . 107
Table 51 Distribution of Induced Pluripotent Stem Cell Patents and Patent Applications with WIPO, by
Filing Office or Country, 2011 to October 2016 (Number/%) . 108
Table 52 Main Inventors of Global Induced Pluripotent Stem Cell Patents or Patent Applications, 2011 to
October 2016 (Number/%) .. 109
Table 53 Main Applicants of Global Induced Pluripotent Stem Cell Patent Applications, 2011 to October
2016 (Number/%) . 110
Table 54 World Intellectual Property Office Induced Pluripotent Stem Cell Patent Publications, by Year,
2007-2016 (Number) .. 110
Table 55 U.S. Patent and Trademark Office Induced Pluripotent Stem Cell Patent Applications, 2009-
2016 (Number) 111
Table 56 Global Distribution of Induced Pluripotent Stem Cell Patents and Patent Applications with
USPTO, by Country, Through 2016 (Number of Patents/%) 112
Table 57 U.S. Induced Pluripotent Stem Cell Patents and Patent Applications by State, Through 2016
(Number/%) . 113
Table 58 World Intellectual Property Organization Induced Pluripotent Stem Cell Patent Publications, by
Category, Through 2016 (Number/%) 114
Table 59 Induced Pluripotent Stem Cell Publications, 2006-2016 (Number) . 114

List of Figures
Summary Figure: Global Induced Pluripotent Stem Cell Market, by Region, 2015-2021 ($ Millions) 8
Figure 1 Global Induced Pluripotent Stem Cell Product Market Shares, by Region, 2021 (%) . 27
Figure 2 U.S. Induced Pluripotent Stem Cell Product Market Shares, by State, 2021 (%) .. 28
Figure 3 Global Market Shares for Generating Induced Pluripotent Stem Cells, by Methods, 2021 (%) 30
Figure 4 Global Market Shares for Generating Induced Pluripotent Stem Cells, by Methods, 2021 (%) 31
Figure 5 Global Market Shares for Induced Pluripotent Stem Cell Products, by Application, 2021 (%) . 32
Figure 6 U.S. Market Shares for Induced Pluripotent Stem Cell Products, by Application, 2021 (%) .. 34
Figure 7 Global Market Shares for Induced Pluripotent Stem Cell-Derived Tissue Cells, by Type, 2021 (%)
.. 35
Figure 8 Major Commercial Induced Pluripotent Stem Cell Suppliers, by Country, 2016 .. 39
Figure 9 Major U.S. Commercial Induced Pluripotent Stem Cell Product Suppliers, by State, 2016 40
Figure 10 Major Commercial Induced Pluripotent Stem Cell Product Manufacturers, by Country, 2016 . 43
Figure 11 Major U.S. Commercial Induced Pluripotent Stem Cell Product Manufacturers, by State, 2016
.. 43
Figure 12 Global Market Shares for Induced Pluripotent Stem Cell-Derived Cells, by Application, 2021 (%)
.. 45
Figure 13 Global Market Shares for Induced Pluripotent Stem Cells, by Product Function, 2021 (%) . 47
Figure 14 U.S. Market Shares for Induced Pluripotent Stem Cells, by Product Function, 2021 (%) .. 48
Figure 15 Global Market Shares for Induced Pluripotent Stem Cells, by Research and Clinical Use, 2021
(%) 50
Figure 16 Global Market Shares for Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes, by
Application, 2021 (%) . 52
Figure 17 U.S. Market Shares for Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes, by
Application, 2021 (%) . 53
Figure 18 European Market for Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes, by
Application, 2021 (%) . 54
Figure 19 Asia-Pacific Market Shares for Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes,
by Application, 2021 (%) .. 56
Figure 20 Global Market Shares for Induced Pluripotent Stem Cell-Derived Human Hepatocytes, by
Application, 2021 (%) . 57
Figure 21 U.S. Market Shares for Induced Pluripotent Stem Cell-Derived Human Hepatocytes, by
Application, 2021 (%) . 59
Figure 22 European Market Shares for Induced Pluripotent Stem Cell-Derived Human Hepatocytes, by
Application, 2021 (%) . 60
Figure 23 Asia-Pacific Market Shares for Induced Pluripotent Stem Cell-Derived Human Hepatocytes, by
Application, 2021 (%) . 61
Figure 24 Global Market Shares for Induced Pluripotent Stem Cell-Derived Human Endothelia Cells, by
Application, 2021 (%) . 62
Figure 25 U.S. Market Shares for Induced Pluripotent Stem Cell-Derived Human Endothelia Cells, by
Application, 2021 (%) . 63
Figure 26 European Market Shares for Induced Pluripotent Stem Cell-Derived Human Endothelia Cells,
by Application, 2021 (%) .. 64
Figure 27 Asia-Pacific Market Shares for Induced Pluripotent Stem Cell-Derived Human Endothelia Cells,
by Application, 2021 (%) .. 65
Figure 28 Global Market Shares for Induced Pluripotent Stem Cell-Derived Human Neural Cells, by
Application, 2021 (%) . 67
Figure 29 U.S. Market Shares for Induced Pluripotent Stem Cell-Derived Human Neural Cells, by
Application, 2021 (%) . 68
Figure 30 European Market Shares for Induced Pluripotent Stem Cell-Derived Human Neural Cells, by
Application, 2021 (%) . 69
Figure 31 Asia-Pacific Market Shares for Induced Pluripotent Stem Cell-Derived Human Neural Cells, by
Application, 2021 (%) . 70
Figure 32 Global Market Shares for Induced Pluripotent Stem Cells and Derivative Cells, by Species, 2021
(%) 71
Figure 33 Global Market Shares for Induced Pluripotent Stem Cell Culture Products, by Region, 2021 (%)
.. 74
Figure 34 Global Market Shares for Induced Pluripotent Stem Cells, by Product Function, 2021 (%) . 77
Figure 35 U.S. Market Shares for Induced Pluripotent Stem Cells, by Product Function, 2021 (%) .. 78
Figure 36 Global Market Shares for Induced Pluripotent Stem Cell-Derived Cell Research, by Cell Type,
2021 (%) 80
Figure 37 Global Market Shares for Induced Pluripotent Stem Cell Research, by Region, 2021 (%) 81
Figure 38 Global Market Shares for Induced Pluripotent Stem Cell-Derived Cells Drug Development and
Toxicity Testing, by Cell Type, 2021 (%) 87
Figure 39 Global Market Shares for Induced Pluripotent Stem Cell Drug Development and Toxicity
Testing, by Region, 2021 (%) .. 88
Figure 40 Global Market Shares for Induced Pluripotent Stem Cell Contract Services, by Region, 2021 (%)
.. 92
Figure 41 Global Market Shares for Induced Pluripotent Stem Cell-Derived Regenerative Medicine, by
Cell Type, 2021 (%) .. 96
Figure 42 Induced Pluripotent Stem Cell Clinical Global Market Shares, by Region, 2021 (%) 97
Figure 43 Major Governmental Induced Pluripotent Stem Cell Research Funding, by Region, 2006-2016
(%) . 100
Figure 44 National Institutes of Health Induced Pluripotent Stem Cell Research Funding, 2006-2016
($ Millions) 101
Figure 45 World Intellectual Property Office Induced Pluripotent Stem Cell Patent Applications, 2007-
2016 (Number) 111
Figure 46 U.S. Patent and Trademark Office Induced Pluripotent Stem Cell Patent Applications, 2009-
2016 (Number) 112
Figure 47 Induced Pluripotent Stem Cell Research Publications, 2006-2016 (Number) .. 115

Country=World Industry=BiologicalTherapy ParentIndustry=Biotechnology Date=201706 Topic=MarketReport Publisher=BCCResearch Price=5000