Amyloidosis - Epidemiology Forecast to 2029

Amyloidosis - Epidemiology Forecast to 2029

  • June 2020 •
  • 48 pages •
  • Report ID: 5930847 •
  • Format: PDF
Amyloidosis - Epidemiology Forecast to 2029

Summary
Amyloidosis is a rare disease characterized by extracellular and/or intracellular deposition of insoluble abnormal amyloid fibrils that alters the normal functions of the tissues in the organs (Holmes et al., 2019; Mayo Clinic, 2020). Amyloid is not normally found in the body, but it can be formed from several different types of protein and interferes with the organs’ normal function. Organs that may be affected by amyloidosis include the heart, kidneys, liver, spleen, nervous system, and digestive tract (Mayo Clinic, 2020).

The signs and symptoms of amyloidosis include dizziness, fluid retention, fatigue, fainting, an enlarged tongue, low blood pressure, and shortness of breath (Mayo Clinic, 2020; Stanford Health Care, 2020). There are different types of amyloidosis, such as immunoglobulin light chain (AL) amyloidosis (referred to as primary amyloidosis), hereditary transthyretin amyloidosis (ATTRh/m) (referred to as hereditary or familial amyloidosis), wild-type transthyretin amyloidosis (ATTR-wt), AA amyloidosis (referred to as secondary amyloidosis), and localized amyloidosis (National Organization for Rare Disorders, 2020; Stanford Health Care, 2020).

In 2019, the 7MM had 10,575 diagnosed incident cases of AL amyloidosis in men and women combined for all ages.The US accounted for the majority of these cases with 4,386 diagnosed incident cases, while the UK accounted for the fewest cases with 468 cases in 2019.

Epidemiologists forecast an increase in the diagnosed incident cases of AL amyloidosis to 12,265 cases in 2029 in the 7MM at an Annual Growth Rate (AGR) of 1.60% during the forecast period. Epidemiologists forecast an increase in the diagnosed incident cases of AL amyloidosis to 16,876 cases in 2029 in the 7MM at an Annual Growth Rate (AGR) of 1.41% during the forecast period. In 2019, there were 75,033 diagnosed prevalent cases of AL amyloidosis in men and women combined, for all ages, in the 7MM. The US accounted for the majority of these cases with 23,350 cases, while Spain accounted for the fewest cases with 5,428 cases in 2019.

Scope
- The Amyloidosis Report provides an overview of the risk factors and the global and historical trends for amyloidosis in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan). The report includes diagnosed incident cases and diagnosed prevalent cases of AL amyloidosis in these markets from 2019-2029.
- The diagnosed incident cases and diagnosed prevalent cases of AL amyloidosis are further segmented by sex and age (all ages), and subtypes (AL cardiomyopathy, AL renal amyloidosis, and AL polyneuropathy).
- The diagnosed prevalent cases of AL amyloidosis are also segmented by Mayo classification stages (stage I, II, III, and IV), and by previous diagnosis of multiple myeloma. The report also includes the diagnosed incident cases and diagnosed prevalent cases of ATTRh/m, ATTR-wt, and AA amyloidosis for all ages and both sexes combined. The diagnosed prevalent cases of ATTRh/m are further segmented by those who undergo liver transplantation.
- The amyloidosis epidemiology report is written and developed by Masters- and PhD-level epidemiologists.
- The Epidemiology Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 7MM.

Reasons to Buy
The Amyloidosis Epidemiology series will allow you to -
- Develop business strategies by understanding the trends shaping and driving the global amyloidosis market.
- Quantify patient populations in the global amyloidosis market to improve product design, pricing, and launch plans.
- Organize sales and marketing efforts by identifying the age groups that present the best opportunities for amyloidosis therapeutics in each of the markets covered.
- Understand magnitude of amyloidosis by types and AL amyloidosis by subtypes.
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