1 INTRODUCTION 12
1.1 OBJECTIVES OF THE STUDY 12
1.2 MARKET DEFINITION 12
1.3 MARKET SCOPE 13
1.3.1 SEGMENTS COVERED 13
1.3.2 GEOGRAPHIC SCOPE 14
1.3.3 YEARS CONSIDERED FOR THE STUDY 14
1.4 CURRENCY 15
1.5 MAJOR MARKET STAKEHOLDERS 15

2 RESEARCH METHODOLOGY 16
2.1 RESEARCH DATA 16
2.1.1 SECONDARY DATA 17
2.1.1.1 Key data from secondary sources 18
2.1.2 PRIMARY DATA 19
2.1.2.1 Key data from primary sources 19
2.2 MARKET SIZE ESTIMATION METHODOLOGY 20
2.2.1 BOTTOM-UP APPROACH 20
2.2.2 TOP-DOWN APPROACH 22
2.3 MARKET ESTIMATION AND DATA TRIANGULATION 23
2.4 RESEARCH ASSUMPTIONS 24
2.5 RESEARCH LIMITATIONS 24

3 EXECUTIVE SUMMARY 25

4 PREMIUM INSIGHTS 29
4.1 STERNAL CLOSURE SYSTEMS: MARKET OVERVIEW 29
4.2 STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2018 VS. 2023 (USD MILLION) 30
4.3 STERNAL CLOSURE SYSTEMS MARKET SHARE, BY PROCEDURE,

2018 VS. 2023 30
4.4 STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY MATERIAL,

2018 VS. 2023 (USD MILLION) 31
4.5 GEOGRAPHICAL SNAPSHOT OF THE STERNAL CLOSURE SYSTEMS MARKET 32

5 MARKET OVERVIEW 33
5.1 INTRODUCTION 33
5.2 MARKET DYNAMICS 33
5.2.1 MARKET DRIVERS 34
5.2.1.1 Technological advancements in sternotomy techniques 34
5.2.1.2 Increasing target patient population coupled with the subsequent increase in the number of surgical procedures 34
5.2.1.3 Growing availability of medical reimbursements across major markets 35
5.2.2 MARKET RESTRAINTS 36
5.2.2.1 Procedural risks associated with sternal closure 36
5.2.2.2 Excise duty, taxes, and legislations for medical devices across the globe 36
5.2.3 MARKET OPPORTUNITIES 37
5.2.3.1 Increasing research activities for sternal closure procedures 37
5.2.3.2 Emerging markets 38
5.2.4 MARKET CHALLENGES 39
5.2.4.1 Dearth of skilled OR technicians & surgeons 39
5.2.4.2 Limited awareness among healthcare providers about novel sternal closure techniques 40

6 STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT 41
6.1 INTRODUCTION 42
6.2 CLOSURE DEVICES 43
6.2.1 WIRES 46
6.2.2 PLATES & SCREWS 49
6.2.3 CABLES 52
6.2.4 CLIPS 54
6.3 BONE CEMENT 57

7 STERNAL CLOSURE SYSTEMS MARKET, BY PROCEDURE 60
7.1 INTRODUCTION 61
7.2 MEDIAN STERNOTOMY 62
7.3 HEMISTERNOTOMY 63
7.4 BILATERAL THORACOSTERNOTOMY 64

8 STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES,
BY MATERIAL 66
8.1 INTRODUCTION 67
8.2 STAINLESS STEEL 68
8.3 POLYETHER ETHER KETONE (PEEK) 69
8.4 TITANIUM 70

9 STERNAL CLOSURE SYSTEMS MARKET, BY REGION 72
9.1 INTRODUCTION 73
9.2 NORTH AMERICA 74
9.2.1 US 76
9.2.2 CANADA 77
9.3 EUROPE 78
9.3.1 GERMANY 81
9.3.2 UK 82
9.3.3 FRANCE 82
9.3.4 REST OF EUROPE (ROE) 83
9.4 ASIA PACIFIC (APAC) 84
9.4.1 JAPAN 87
9.4.2 CHINA 87
9.4.3 INDIA 88
9.4.4 REST OF ASIA PACIFIC (ROAPAC) 89
9.5 REST OF THE WORLD 90

10 COMPETITIVE LANDSCAPE 92
10.1 OVERVIEW 92
10.2 GLOBAL MARKET RANKING (2017) 92
10.3 COMPETITIVE SCENARIO 93
10.3.1 KEY PRODUCT LAUNCHES, 2015-2018 93
10.3.2 KEY MERGERS AND ACQUISITIONS, 2015-2018 93

11 COMPANY PROFILES 94

(Introduction, Products & Services, Strategy, & Analyst Insights, Developments, MnM View)*
11.1 DEPUY SYNTHES (A PART OF JOHNSON & JOHNSON) 94
11.2 ZIMMER BIOMET HOLDINGS 96
11.3 KLS MARTIN GROUP 98
11.4 ACUTE INNOVATIONS 99
11.5 ORTHOFIX INTERNATIONAL N.V. 100
11.6 A&E MEDICAL 102
11.7 IDEAR S.R.L 104
11.8 PRAESIDIA SRL 105
11.9 KINAMED INCORPORATED 106
11.10 MEDIA GROUP AUSTRALIA PTY LTD 107
11.11 JACE MEDICAL 108
11.12 ABYRX 109
11.13 DISPOMEDICA 110
11.14 JEIL MEDICAL CORPORATION 111
11.15 CHANGZHOU WASTON MEDICAL APPLIANCE COMPANY LIMITED 112

*Details on MarketsandMarkets view, Introduction, Product & Services, Strategy, & Analyst Insights, New Developments might not be captured in case of unlisted companies.

12 APPENDIX 113
12.1 DISCUSSION GUIDE 113
12.2 KNOWLEDGE STORE: MARKETSANDMARKETS' SUBSCRIPTION PORTAL 117
12.3 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE 119
12.4 AVAILABLE CUSTOMIZATIONS 121
12.5 RELATED REPORTS 122
12.6 AUTHOR DETAILS 123

LIST OF TABLES
TABLE 1 KEY REIMBURSEMENT CODES FOR STERNAL CLOSURE (AS OF 2017) 35
TABLE 2 STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 42
TABLE 3 STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY TYPE, 2016-2023 (USD MILLION) 43
TABLE 4 GLOBAL STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 44
TABLE 5 STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY REGION, 2016-2023 (USD MILLION) 44
TABLE 6 NORTH AMERICAN STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 45
TABLE 7 EUROPEAN STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 45
TABLE 8 APAC STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 46
TABLE 9 GLOBAL STERNAL CLOSURE SYSTEMS MARKET FOR WIRE CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 47
TABLE 10 STERNAL CLOSURE SYSTEMS MARKET FOR WIRE CLOSURE DEVICES, BY REGION, 2016-2023 (USD MILLION) 47
TABLE 11 NORTH AMERICAN STERNAL CLOSURE SYSTEMS MARKET FOR WIRE CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 48
TABLE 12 EUROPEAN STERNAL CLOSURE SYSTEMS MARKET FOR WIRE CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 48
TABLE 13 APAC STERNAL CLOSURE SYSTEMS MARKET FOR WIRE CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 49
TABLE 14 GLOBAL STERNAL CLOSURE SYSTEMS MARKET FOR PLATE & SCREW CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 49
TABLE 15 STERNAL CLOSURE SYSTEMS MARKET FOR PLATE & SCREW CLOSURE DEVICES, BY REGION, 2016-2023 (USD MILLION) 50
TABLE 16 NORTH AMERICAN STERNAL CLOSURE SYSTEMS MARKET FOR PLATE & SCREW CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 50
TABLE 17 EUROPEAN STERNAL CLOSURE SYSTEMS MARKET FOR PLATE & SCREW CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 51
TABLE 18 APAC STERNAL CLOSURE SYSTEMS MARKET FOR PLATE & SCREW CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 51
TABLE 19 GLOBAL STERNAL CLOSURE SYSTEMS MARKET FOR CABLE CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 52
TABLE 20 STERNAL CLOSURE SYSTEMS MARKET FOR CABLE CLOSURE DEVICES, BY REGION, 2016-2023 (USD MILLION) 52
TABLE 21 NORTH AMERICAN STERNAL CLOSURE SYSTEMS MARKET FOR CABLE CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 53
TABLE 22 EUROPEAN STERNAL CLOSURE SYSTEMS MARKET FOR CABLE CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 53
TABLE 23 APAC STERNAL CLOSURE SYSTEMS MARKET FOR CABLE CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 54
TABLE 24 GLOBAL STERNAL CLOSURE SYSTEMS MARKET FOR CLIP CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 54
TABLE 25 STERNAL CLOSURE SYSTEMS MARKET FOR CLIP CLOSURE DEVICES, BY REGION, 2016-2023 (USD MILLION) 55
TABLE 26 NORTH AMERICAN STERNAL CLOSURE SYSTEMS MARKET FOR CLIP CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 55
TABLE 27 EUROPEAN STERNAL CLOSURE SYSTEMS MARKET FOR CLIP CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 56
TABLE 28 APAC STERNAL CLOSURE SYSTEMS MARKET FOR CLIP CLOSURE DEVICES, BY COUNTRY, 2016-2023 (USD MILLION) 56
TABLE 29 STERNAL CLOSURE SYSTEMS MARKET FOR BONE CEMENT, BY REGION, 2016-2023 (USD MILLION) 57
TABLE 30 NORTH AMERICAN STERNAL CLOSURE SYSTEMS MARKET FOR BONE CEMENT, BY COUNTRY, 2016-2023 (USD MILLION) 58
TABLE 31 EUROPE STERNAL CLOSURE SYSTEMS MARKET FOR BONE CEMENT, BY COUNTRY, 2016-2023 (USD MILLION) 58
TABLE 32 APAC STERNAL CLOSURE SYSTEMS MARKET FOR BONE CEMENT, BY COUNTRY, 2016-2023 (USD MILLION) 59
TABLE 33 STERNAL CLOSURE SYSTEMS MARKET, BY PROCEDURE, 2016-2023 (USD MILLION) 61
TABLE 34 STERNAL CLOSURE SYSTEMS MARKET FOR MEDIAN STERNOTOMY, BY REGION, 2016-2023 (USD MILLION) 62
TABLE 35 STERNAL CLOSURE SYSTEMS MARKET FOR HEMISTERNOTOMY, BY REGION, 2016-2023 (USD MILLION) 63
TABLE 36 STERNAL CLOSURE SYSTEMS MARKET FOR BILATERAL THORACOSTERNOTOMY, BY REGION, 2016-2023 (USD MILLION) 65
TABLE 37 STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 67
TABLE 38 STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY REGION, 2016-2023 (USD MILLION) 68
TABLE 39 STERNAL CLOSURE SYSTEMS MARKET FOR STAINLESS STEEL-BASED CLOSURE DEVICES, BY REGION, 2016-2023 (USD MILLION) 69
TABLE 40 STERNAL CLOSURE SYSTEMS MARKET FOR PEEK-BASED CLOSURE DEVICES, BY REGION, 2016-2023 (USD MILLION) 70
TABLE 41 STERNAL CLOSURE SYSTEMS MARKET FOR TITANIUM-BASED CLOSURE DEVICES, BY REGION, 2016-2023 (USD MILLION) 71
TABLE 42 STERNAL CLOSURE SYSTEMS MARKET, BY REGION, 2016-2023 (USD MILLION) 73
TABLE 43 NORTH AMERICA: STERNAL CLOSURE SYSTEMS MARKET, BY COUNTRY, 2016-2023 (USD MILLION) 75
TABLE 44 NORTH AMERICA: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 75
TABLE 45 NORTH AMERICA: STERNAL CLOSURE SYSTEMS MARKET, BY PROCEDURE, 2016-2023 (USD MILLION) 75
TABLE 46 NORTH AMERICA: STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 76
TABLE 47 KEY REIMBURSEMENT CODES FOR STERNAL CLOSURE IN THE US (AS OF 2017) 76
TABLE 48 US: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 77
TABLE 49 CANADA: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 77
TABLE 50 EUROPE: STERNAL CLOSURE SYSTEMS MARKET, BY COUNTRY, 2016-2023 (USD MILLION) 80
TABLE 51 EUROPE: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 80
TABLE 52 EUROPE: STERNAL CLOSURE SYSTEMS MARKET, BY PROCEDURE, 2016-2023 (USD MILLION) 80
TABLE 53 EUROPE: STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 81
TABLE 54 GERMANY: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 81
TABLE 55 UK: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 82
TABLE 56 FRANCE: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 83
TABLE 57 ROE: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 83
TABLE 58 ASIA PACIFIC: STERNAL CLOSURE SYSTEMS MARKET, BY COUNTRY, 2016-2023 (USD MILLION) 85
TABLE 59 ASIA PACIFIC: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 85
TABLE 60 ASIA PACIFIC: STERNAL CLOSURE SYSTEMS MARKET, BY PROCEDURE, 2016-2023 (USD MILLION) 86
TABLE 61 ASIA PACIFIC: STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 86
TABLE 62 JAPAN: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 87
TABLE 63 CHINA: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 88
TABLE 64 INDIA: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 88
TABLE 65 ROAPAC: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 89
TABLE 66 ROW: STERNAL CLOSURE SYSTEMS MARKET, BY PRODUCT, 2016-2023 (USD MILLION) 90
TABLE 67 ROW: STERNAL CLOSURE SYSTEMS MARKET, BY PROCEDURE, 2016-2023 (USD MILLION) 90
TABLE 68 ROW: STERNAL CLOSURE SYSTEMS MARKET FOR CLOSURE DEVICES, BY MATERIAL, 2016-2023 (USD MILLION) 91
TABLE 69 STERNAL CLOSURE SYSTEMS MARKET RANKING, BY KEY PLAYERS (2017) 92

LIST OF FIGURES
FIGURE 1 GLOBAL STERNAL CLOSURE SYSTEM MARKET: RESEARCH METHODOLOGY STEPS 16
FIGURE 2 RESEARCH DESIGN 17
FIGURE 3 PRIMARY RESEARCH FRAMEWORK: BREAKDOWN OF PRIMARY RESPONDENTS 20
FIGURE 4 BOTTOM-UP APPROACH: PRODUCT SALES-BASED ANALYSIS 21
FIGURE 5 BOTTOM-UP APPROACH: REVENUE-BASED ANALYSIS 21
FIGURE 6 TOP-DOWN APPROACH 22
FIGURE 7 MARKET ESTIMATION AND DATA TRIANGULATION METHODOLOGY 23
FIGURE 8 STERNAL CLOSURE SYSTEMS MARKET SHARE, BY PRODUCT (2017) 25
FIGURE 9 STERNAL CLOSURE SYSTEMS MARKET, BY PROCEDURE, 2017 (USD MILLION) 26
FIGURE 10 STERNAL CLOSURE D MARKET FOR CLOSURE DEVICES, BY MATERIAL, 2017 (USD MILLION) 27
FIGURE 11 NORTH AMERICA DOMINATED THE STERNAL CLOSURE SYSTEMS MARKET IN 2017 28
FIGURE 12 GLOBAL STERNAL CLOSURE SYSTEMS MARKET TO OFFER SIGNIFICANT GROWTH OPPORTUNITIES TO MAJOR STAKEHOLDERS DURING THE NEXT DECADE 29
FIGURE 13 CLOSURE DEVICES TO DOMINATE THE STERNAL CLOSURE SYSTEMS MARKET IN 2018 30
FIGURE 14 MEDIAN STERNOTOMY SEGMENT WILL CONTINUE TO DOMINATE THE STERNAL CLOSURE SYSTEMS MARKET IN 2023 30
FIGURE 15 TITANIUM SEGMENT TO WITNESS THE HIGHEST GROWTH DURING THE FORECAST PERIOD 31
FIGURE 16 ASIA PACIFIC TO REGISTER THE HIGHEST GROWTH RATE DURING THE FORECAST PERIOD 32
FIGURE 17 STERNAL CLOSURE SYSTEMS MARKET: DRIVERS, RESTRAINTS, & OPPORTUNITIES 33
FIGURE 18 ANNUAL HEALTHCARE EXPENDITURE (%GDP): DEVELOPED VS. DEVELOPING COUNTRIES (2010-2016) 38
FIGURE 19 CLOSURE DEVICES TO WITNESS THE HIGHEST GROWTH DURING THE FORECAST PERIOD 42
FIGURE 20 MEDIAN STERNOTOMY SEGMENT TO WITNESS THE HIGHEST GROWTH IN THE STERNAL CLOSURE SYSTEMS MARKET DURING THE FORECAST PERIOD 61
FIGURE 21 TITANIUM SEGMENT TO WITNESS THE HIGHEST GROWTH DURING THE FORECAST PERIOD 67
FIGURE 22 NORTH AMERICA: STERNAL CLOSURE SYSTEMS MARKET SNAPSHOT 74
FIGURE 23 EUROPE: STERNAL CLOSURE SYSTEMS MARKET SNAPSHOT 79
FIGURE 24 ASIA PACIFIC: STERNAL CLOSURE SYSTEMS MARKET SNAPSHOT 84
FIGURE 25 KEY DEVELOPMENTS IN THE STERNAL CLOSURE SYSTEMS MARKET, 2015-2017 92
FIGURE 26 JOHNSON & JOHNSON: COMPANY SNAPSHOT (2017) 94
FIGURE 27 ZIMMER BIOMET HOLDINGS: COMPANY SNAPSHOT (2017) 96
FIGURE 28 ORTHOFIX INTERNATIONAL N.V.: COMPANY SNAPSHOT (2017) 100