1 Executive Summary

2 Gaucher Disease: Overview

Signs and Symptoms
Advancement in Gaucher Disease
Classification
Variants of Gaucher Disease
Etiology
Pathophysiology
Inheritance Pattern
Complications
Diagnosis
Diagnostic Algorithm
Gaucher Disease patients with Ashkenazi Origin
Gaucher Disease patients with Non- Ashkenazi Origin

3 Treatment
Treatment Algorithm
Treatment Guidelines
Screening and Management Guidelines of Hematological Malignancy
Criteria for using Enzyme Replacement Therapy
Treatment Recommendation for Adults with Gaucher Disease Type 1

4 Epidemiology
United States
Prevalent Cases of Gaucher Disease
Sub-type Specific Prevalent Cases of Gaucher Disease
Diagnosed Cases of Gaucher Disease
Age-Specific Diagnosed Cases for Gaucher Disease
Germany
Prevalent Cases of Gaucher Disease
Sub-type Specific Prevalent Cases of Gaucher Disease
Diagnosed Cases of Gaucher Disease
Age-Specific Diagnosed Cases for Gaucher Disease
France
Prevalent Cases of Gaucher Disease
Sub-type Specific Prevalent Cases of Gaucher Disease
Diagnosed Cases of Gaucher Disease
Age-Specific Diagnosed Cases for Gaucher Disease
United Kingdom
Prevalent Cases of Gaucher Disease
Sub-type Specific Prevalent Cases of Gaucher Disease
Diagnosed Cases of Gaucher Disease
Gaucher Disease Market Report 2018
Age-Specific Diagnosed Cases for Gaucher Disease
Spain
Prevalent Cases of Gaucher Disease
Sub-type Specific Prevalent Cases of Gaucher Disease
Diagnosed Cases of Gaucher Disease
Age-Specific Diagnosed Cases for Gaucher Disease
Italy
Prevalent Cases of Gaucher Disease
Sub-type Specific Prevalent Cases of Gaucher Disease
Diagnosed Cases of Gaucher Disease
Age-Specific Diagnosed Cases for Gaucher Disease
Japan
Prevalent Cases of Gaucher Disease
Sub-type Specific Prevalent Cases of Gaucher Disease
Diagnosed Cases of Gaucher Disease
Age-Specific Diagnosed Cases for Gaucher Disease

5 Market Size of Gaucher Disease
United States
Market Size of Gaucher Disease
Therapy wise market Size of Gaucher Disease
EU5
Germany
France
United Kingdom
Spain
Italy
Japan
Market Size of Gaucher Disease
Therapy wise market Size of Gaucher Disease

6 Therapeutic Approaches for Gaucher Disease

7 Competitive Landscape

8 Marketed Drug Profiles

Cerdelga (eliglustat)
Drug Description
Development Activities
Pharmacokinetics
Pharmacodynamics
Adverse Events
Cerdelga Sales
Cerezyme (imiglucerase)
Drug Description
Development Activities
Gaucher Disease Market Report 2018
Pharmacokinetics
Pharmacodynamics
Adverse Events
Cerezyme Sales
Vpriv (velaglucerase alfa)
Drug Description
Development Activities
Pharmacokinetics
Adverse Events
Vpriv Sales
Zavesca (Miglustat)
Drug Description
Development Activities
Pharmacokinetics
Adverse Events
Zavesca Sales
Elelyso (taliglucerase alfa)
Drug Description
Development Activities
Pharmacokinetics
Adverse Events
Elelyso Sales

9 Marketed Drug Analysis
Marketed Drug Analysis by Molecule Type
Marketed Drug Analysis by Route of Administration

10 Pipeline Product Analysis
Pipeline Analysis by Stage of Development
Pipeline Analysis by Route of Administration
Pipeline Analysis by Therapeutic Class
Pipeline Analysis by Targets
Pipeline Analysis by Molecule Type

11 Patent Landscape
Gaucher Disease Patent Trend by Focus Area
Gaucher Disease Patent Trend by Composition
Gaucher Disease Patent Trends by Enzyme Replacement Therapy
Gaucher Disease Patent Trends by Substrate Reduction Therapy
Gaucher Disease Composition patent trends by Supportive Therapies
Gaucher Disease Patent Trends by Route of Administration
Key Patents of Gaucher Disease
Gaucher Disease Patent trends by Key Players
Key players in patent focus
Key Players in Composition
Gaucher Disease Market Report 2018
Collaborations of the Assignees
Gaucher Disease Patents Trends by Key Inventors

12 Market Dynamics
Growth Drivers
Technological advancement
Emerging Therapies
Increasing Research Activities
Challenges
Diagnostic Barriers
Socioeconomic Barriers

13 Companies Profiles
Pfizer
Business Overview
Financial Overview
Sanofi
Business Overview
Financial Overview
Shire Pharmaceuticals
Business Overview
Financial Overview
Johnson & Johnson
Business Overview
Financial Overview

14 About EffeMarket

15 Disclaimer

16 Contact US


Companies Mentioned
. Belrose Pharma, Sanofi-Genzyme, AVROBIO, Inc, Lixte Biotechnology Holdings, Inc., Orphazyme A.S