1 EXECUTIVE SUMMARY 23

2 INTRODUCTION 31
2.1 KEY TAKEAWAYS 31
2.2 SCOPE OF THE REPORT 32
2.3 REPORT DESCRIPTION 32
2.4 MARKETS COVERED 36
2.5 STAKEHOLDERS 37
2.6 RESEARCH METHODOLOGY 38
2.6.1 MARKET SIZE ESTIMATION 40
2.6.2 MARKET BREAKDOWN AND DATA TRIANGULATION 42
2.6.3 SECONDARY SOURCES 43
2.6.4 PRIMARY SOURCES 44
2.6.5 KEY DATA POINTS FROM SECONDARY SOURCES 44
2.6.6 KEY DATA POINTS FROM PRIMARY SOURCES 45
2.6.7 ASSUMPTIONS 45

3 MARKET ANALYSIS 48
3.1 INTRODUCTION 48
3.2 MARKET SEGMENTATION 50
3.3 FACTORS INFLUENCING MARKET 52
3.3.1 DRIVERS AND OPPORTUNITIES 53
3.3.1.1 High prevalence and incidence of orthopaedic disorders and an increase in the aging population 53
3.3.1.2 Increase in accidents and sports injuries 55
3.3.1.3 Increasing demand for minimally invasive surgeries 56
3.3.1.4 Technological advancements 58
3.3.1.5 Acquisition and collaborations as a part of the growth strategy 60
3.3.2 RESTRAINTS AND THREATS 62
3.3.2.1 Product recalls due to manufacturing errors 62
3.3.2.2 Lack of skilled orthopaedic surgeon 63
3.3.2.3 Adverse events and complications with the implantations of orthopaedic devices 64
3.3.2.4 High cost of orthopaedic implants and surgery 64
3.3.2.5 Stringent regulatory policies 65
3.4 REGULATORY AFFAIRS 67
3.4.1 INTERNATIONAL ORGANIZATION FOR STANDARDIZATION 67
3.4.1.1 ISO 9001: 2015 quality management system 67
3.4.1.2 ISO 13485 medical devices 68
3.4.1.3 ISO /TS 16782: 2016 clinical laboratory testing 68
3.4.1.4 ISO 10993 biological evaluation of medical devices 68
3.4.2 THE U.S. 69
3.4.3 CANADA 71
3.4.4 EUROPE 72
3.4.5 JAPAN 73
3.4.6 CHINA 74
3.4.7 INDIA 76
3.5 TECHNOLOGICAL ADVANCEMENTS 79
3.5.1 INTRODUCTION 79
3.5.2 3D PRINTING AND DEVELOPMENT OF PATIENT-SPECIFIC IMPLANTS 79
3.5.3 IMPLANT MATERIALS AND COATINGS 80
3.5.4 SMART IMPLANTS 81
3.5.5 EVOLUTION IN THE ROBOTIC-ASSISTED SURGERY WITH SMALLER INCISION AND POST-OPERATIVE CARE REDUCTION 83
3.6 IMPLANT MATERIALS AND COATINGS 83
3.6.1 METALS 84
3.6.2 CERAMICS AND BIOGLASS 87
3.6.3 POLYMER 89
3.7 PORTER'S FIVE FORCE ANALYSIS 91
3.7.1 THREAT OF NEW ENTRANTS 92
3.7.2 THREAT OF SUBSTITUTES 93
3.7.3 RIVALRY AMONG EXISTING PLAYERS 94
3.7.4 BARGAINING POWER OF SUPPLIERS 96
3.7.5 BARGAINING POWER OF BUYERS 97
3.8 SUPPLY CHAIN ANALYSIS 99
3.9 REIMBURSEMENT SCENARIO 107
3.10 PATENT SCENARIO 113
3.11 FUNDING SCENARIO 115
3.12 MARKET SHARE ANALYSIS BY MAJOR PLAYERS 119
3.12.1 ORTHOPAEDIC DEVICES GLOBAL MARKET SHARE ANALYSIS 119
3.12.2 KNEE GLOBAL MARKET SHARE ANALYSIS 123
3.12.3 HIP GLOBAL MARKET SHARE ANALYSIS 125
3.12.4 SPINE GLOBAL MARKET SHARE ANALYSIS 127
3.12.5 TRAUMA GLOBAL MARKET SHARE ANALYSIS 129
3.12.6 SPORTS MEDICINE GLOBAL MARKET SHARE ANALYSIS 131
3.12.7 ORTHOBIOLOGICS GLOBAL MARKET SHARE ANALYSIS 133
3.12.8 SHOULDER GLOBAL MARKET SHARE ANALYSIS 135
3.12.9 FOOT & ANKLE GLOBAL MARKET SHARE ANALYSIS 137
3.13 ORTHOPAEDIC DEVICES NUMBER OF PROCEDURES BY REGION 139
3.13.1 KNEE ARTHROPLASTY PROCEDURAL VOLUME BY REGION 139
3.13.2 HIP ARTHROPLASTY PROCEDURAL VOLUME BY REGION 146
3.13.3 SPINE ARTHROPLASTY PROCEDURAL VOLUME BY REGION 154
3.13.4 SHOULDER ARTHROPLASTY PROCEDURAL VOLUME BY REGION 157
3.14 ORTHOPAEDIC DEVICES COMPANY COMPARISON TABLE BY REVENUE, PRODUCT, MATERIAL, AND APPLICATION 165

4 ORTHOPAEDIC DEVICES GLOBAL MARKET, BY PRODUCT 184
4.1 INTRODUCTION 184
4.2 KNEE 188
4.3 HIP 195
4.4 EXTREMITIES 201
4.4.1 UPPER EXTREMITIES 206
4.4.1.1 Shoulder 209
4.4.1.2 Other upper extremities 215
4.4.2 LOWER EXTREMITIES 218
4.5 SPINE 221
4.5.1 FUSION DEVICES 227
4.5.1.1 Cervical devices 231
4.5.1.2 Thoracolumbar devices 237
4.5.1.3 Interbody devices 240
4.5.2 NON-FUSION 244
4.5.2.1 Artificial discs 249
4.5.2.2 Dynamic stabilization devices 252
4.5.2.3 Annulus repair devices 256
4.6 CRANIOMAXILLOFACIAL 257
4.7 TRAUMA 260
4.8 SPORTS MEDICINE 267
4.9 ORTHOBIOLOGICS 269
4.9.1 SYNTHETICS 273
4.9.2 DEMINERALIZED BONE MATRIX 275
4.9.3 MACHINED BONE ALLOGRAFT 277
4.9.4 OTHER ORTHOBIOLOGICS 280

5 ORTHOPAEDIC GLOBAL MARKET, BY SURGERY TYPE 281
5.1 INTRODUCTION 281
5.2 OPEN SURGERY 284
5.3 MINIMALLY INVASIVE SURGERY 287
5.4 ROBOTIC ASSISTED SURGERY 291

6 ORTHOPAEDIC DEVICES GLOBAL MARKET, BY END-USERS 294
6.1 INTRODUCTION 294
6.2 HOSPITALS 297
6.3 AMBULATORY SURGICAL CENTERS 299
6.4 ORTHOPAEDIC CLINICS 301

7 REGIONAL ANALYSIS 303
7.1 INTRODUCTION 303
7.2 NORTH AMERICA 307
7.2.1 U.S. 326
7.2.2 REST OF NORTH AMERICA 331
7.3 EUROPE 336
7.3.1 GERMANY 356
7.3.2 FRANCE 360
7.3.3 U.K. 363
7.3.4 REST OF EUROPE 367
7.4 APAC 370
7.4.1 JAPAN 391
7.4.2 INDIA 395
7.4.3 CHINA 398
7.4.4 REST OF APAC 401
7.5 ROW 405
7.5.1 BRAZIL 424
7.5.2 REST OF LATIN AMERICA 427
7.5.3 MIDDLE EAST AND OTHERS 430

8 COMPETITIVE LANDSCAPE 433
8.1 INTRODUCTION 433
8.2 PRODUCT LAUNCH 434
8.3 PRODUCT APPROVAL 439
8.4 ACQUISITION 441
8.5 AGREEMENTS 443
8.6 OTHER DEVELOPMENTS 444

9 MAJOR COMPANIES 445
9.1 ARTHREX INC 445
9.1.1 OVERVIEW 445
9.1.2 FINANCIALS 446
9.1.3 PRODUCT PORTFOLIO 446
9.1.4 KEY DEVELOPMENTS 448
9.1.5 BUSINESS STRATEGY 448
9.1.6 SWOT ANALYSIS 449
9.2 B. BRAUN MELSUNGEN AG 450
9.2.1 OVERVIEW 450
9.2.2 FINANCIALS 451
9.2.3 PRODUCT PORTFOLIO 454
9.2.4 KEY DEVELOPMENTS 455
9.2.5 BUSINESS STRATEGY 455
9.2.6 SWOT ANALYSIS 456
9.3 COLFAX CORPORATION (DJO, LLC) 457
9.3.1 OVERVIEW 457
9.3.2 FINANCIALS 458
9.3.3 PRODUCT PORTFOLIO 460
9.3.4 KEY DEVELOPMENTS 460
9.3.5 BUSINESS STRATEGY 461
9.3.6 SWOT ANALYSIS 462
9.4 GLOBUS MEDICAL, INC. 463
9.4.1 OVERVIEW 463
9.4.2 FINANCIALS 464
9.4.3 PRODUCT PORTFOLIO 467
9.4.4 KEY DEVELOPMENTS 470
9.4.5 BUSINESS STRATEGY 471
9.4.6 SWOT ANALYSIS 472
9.5 JOHNSON & JOHNSON (DEPUY SYNTHES) 473
9.5.1 OVERVIEW 473
9.5.2 FINANCIALS 474
9.5.3 PRODUCT PORTFOLIO 479
9.5.4 KEY DEVELOPMENTS 482
9.5.5 BUSINESS STRATEGY 484
9.5.6 SWOT ANALYSIS 485
9.6 MEDTRONIC PUBLIC LIMITED COMPANY 486
9.6.1 OVERVIEW 486
9.6.2 FINANCIALS 487
9.6.3 PRODUCT PORTFOLIO 490
9.6.4 KEY DEVELOPMENTS 490
9.6.5 BUSINESS STRATEGY 491
9.6.6 SWOT ANALYSIS 492
9.7 NUVASIVE INC. 493
9.7.1 OVERVIEW 493
9.7.2 FINANCIALS 494
9.7.3 PRODUCT PORTFOLIO 497
9.7.4 KEY DEVELOPMENTS 497
9.7.5 BUSINESS STRATEGY 501
9.7.6 SWOT ANALYSIS 502
9.8 SMITH & NEPHEW PLC, PLC. 503
9.8.1 OVERVIEW 503
9.8.2 FINANCIALS 504
9.8.3 PRODUCT PORTFOLIO 509
9.8.4 KEY DEVELOPMENTS 512
9.8.5 BUSINESS STRATEGY 514
9.8.6 SWOT ANALYSIS 515
9.9 STRYKER CORPORATION 516
9.9.1 OVERVIEW 516
9.9.2 FINANCIALS 517
9.9.3 PRODUCT PORTFOLIO 522
9.9.4 KEY DEVELOPMENTS 526
9.9.5 BUSINESS STRATEGY 529
9.9.6 SWOT ANALYSIS 530
9.10 ZIMMER BIOMET HOLDINGS, INC 531
9.10.1 OVERVIEW 531
9.10.2 FINANCIALS 532
9.10.3 PRODUCT PORTFOLIO 535
9.10.4 KEY DEVELOPMENTS 542
9.10.5 BUSINESS STRATEGY 544
9.10.6 SWOT ANALYSIS 545

LIST OF TABLES
TABLE 1 ORTHOPAEDIC DEVICES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 29
TABLE 2 AVERAGE SELLING PRICE (ASP) OF HIP, KNEE, SHOULDER AND SPINE IMPLANTS (2020) ($) 47
TABLE 3 ORTHOPAEDIC DEVICES FUNDINGS 117
TABLE 4 KNEE ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 140
TABLE 5 TOTAL KNEE ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 142
TABLE 6 UNICONDYLAR KNEE ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 144
TABLE 7 REVISION KNEE ARTHROPLASTY ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 145
TABLE 8 HIP ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 147
TABLE 9 TOTAL HIP ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 149
TABLE 10 PARTIAL HIP ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 151
TABLE 11 HIP RESURFACING ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 152
TABLE 12 REVISION HIP ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 153
TABLE 13 SPINE ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 155
TABLE 14 SHOULDER ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 158
TABLE 15 PRIMARY TOTAL SHOULDER ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 160
TABLE 16 REVERSE SHOULDER ARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 162
TABLE 17 SHOULDER HEMIARTHROPLASTY PROCEDURE, BY REGION, (2019-2027) (NO'S) 163
TABLE 18 SHOULDER RESURFACING PROCEDURE, BY REGION, (2019-2027) (NO'S) 164
TABLE 19 ORTHOPAEDIC DEVICES GLOBAL MARKET REVENUE, BY PRODUCT, (2019-2027) ($MN) 186
TABLE 20 KNEE GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 189
TABLE 21 HIP GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 196
TABLE 22 EXTREMITIES GLOBAL MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 203
TABLE 23 EXTREMITIES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 205
TABLE 24 UPPER EXTREMITIES GLOBAL MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 207
TABLE 25 UPPER EXTREMITIES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 208
TABLE 26 SHOULDER GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 214
TABLE 27 OTHER UPPER EXTREMITIES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 217
TABLE 28 LOWER EXTREMITIES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 220
TABLE 29 SPINE GLOBAL MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 224
TABLE 30 SPINE GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 226
TABLE 31 FUSION DEVICES GLOBAL MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 228
TABLE 32 FUSION DEVICES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 230
TABLE 33 CERVICAL DEVICES MARKET REVENUE, BY REGION, (2019-2027) ($MN) 236
TABLE 34 THORACOLUMBAR DEVICES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 239
TABLE 35 INTERBODY DEVICES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 243
TABLE 36 NON-FUSION GLOBAL MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 245
TABLE 37 NON-FUSION DEVICES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 247
TABLE 38 ARTIFICIAL DISCS MARKET REVENUE, BY REGION, (2019-2027) ($MN) 250
TABLE 39 DYNAMIC STABILIZATION DEVICES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 255
TABLE 40 ANNULUS REPAIR DEVICES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 256
TABLE 41 CRANIOMAXILLOFACIAL GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 259
TABLE 42 TRAUMA GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 265
TABLE 43 SPORTS MEDICINE GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 268
TABLE 44 ORTHOBIOLOGICS GLOBAL MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 270
TABLE 45 ORTHOBIOLOGICS GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 272
TABLE 46 SYNTHETICS GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 274
TABLE 47 DEMINERALIZED BONE MATRIX GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 276
TABLE 48 MACHINED BONE ALLOGRAFT GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 279
TABLE 49 OTHER ORTHOBIOLOGICS GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 280
TABLE 50 ORTHPAEDIC DEVICES GLOBAL MARKET REVENUE, BY SURGERY TYPE, (2019-2027) ($MN) 282
TABLE 51 OPEN SURGERY GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 285
TABLE 52 MINIMALLY INVASIVE SURGERY GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 289
TABLE 53 ROBOTIC-ASSISTED SURGERY GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 293
TABLE 54 GLOBAL ORTHOPAEDIC DEVICES MARKET REVENUE, BY END-USERS (2019-2027) ($MN) 295
TABLE 55 HOSPITALS GLOBAL MARKET REVENUE, BY REGION (2019-2027) ($MN) 298
TABLE 56 AMBULATORY SURGICAL CENTERS GLOBAL MARKET REVENUE, BY REGION (2019-2027) ($MN) 300
TABLE 57 ORTHOPAEDIC CLINICS GLOBAL MARKET REVENUE, BY REGION (2019-2027) ($MN) 302
TABLE 58 ORTHOPAEDIC DEVICES GLOBAL MARKET REVENUE, BY REGION, (2019-2027) ($MN) 304
TABLE 59 NORTH AMERICA ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, (2019-2027) ($MN) 310
TABLE 60 NORTH AMERICA EXTREMITIES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 311
TABLE 61 NORTH AMERICA UPPER EXTREMITIES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 312
TABLE 62 NORTH AMERICA SPINE MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 313
TABLE 63 NORTH AMERICA FUSION DEVICES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 314
TABLE 64 NORTH AMERICA NON-FUSION DEVICES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 315
TABLE 65 NORTH AMERICA ORTHOBIOLOGICS MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 316
TABLE 66 NORTH AMERICA ORTHOPAEDIC DEVICES MARKET REVENUE, BY SURGERY TYPE, (2019-2027) ($MN) 317
TABLE 67 NORTH AMERICA ORTHOPAEDIC DEVICES MARKET REVENUE, BY END-USERS (2019-2027) ($MN) 318
TABLE 68 NORTH AMERICA ORTHOPAEDIC DEVICES MARKET REVENUE, BY COUNTRY, (2019-2027) ($MN) 324
TABLE 69 EUROPE ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, (2019-2027) ($MN) 340
TABLE 70 EUROPE EXTREMITIES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 341
TABLE 71 EUROPE UPPER EXTREMITIES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 342
TABLE 72 EUROPE SPINE MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 343
TABLE 73 EUROPE FUSION DEVICES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 344
TABLE 74 EUROPE NON-FUSION DEVICES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 345
TABLE 75 EUROPE ORTHOBIOLOGICS MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 346
TABLE 76 EUROPE ORTHOPAEDIC DEVICES MARKET REVENUE, BY SURGERY TYPE, (2019-2027) ($MN) 347
TABLE 77 EUROPE ORTHOPAEDIC DEVICES MARKET REVENUE, BY END-USERS (2019-2027) ($MN) 348
TABLE 78 EUROPE ORTHOPAEDIC DEVICES MARKET REVENUE, BY COUNTRY, (2019-2027) ($MN) 354
TABLE 79 ASIA-PACIFIC ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, (2019-2027) ($MN) 375
TABLE 80 ASIA-PACIFIC EXTREMITIES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 376
TABLE 81 ASIA-PACIFIC UPPER EXTREMITIES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 377
TABLE 82 ASIA-PACIFIC SPINE MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 378
TABLE 83 ASIA-PACIFIC FUSION DEVICES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 379
TABLE 84 ASIA-PACIFIC NON-FUSION DEVICES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 380
TABLE 85 ASIA-PACIFIC ORTHOBIOLOGICS MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 381
TABLE 86 APAC ORTHOPAEDIC DEVICES MARKET REVENUE, BY SURGERY TYPE, (2019-2027) ($MN) 382
TABLE 87 ASIA-PACIFIC ORTHOPAEDIC DEVICES MARKET REVENUE, BY END-USERS (2019-2027) ($MN) 383
TABLE 88 ASIA-PACIFIC ORTHOPAEDIC DEVICES MARKET REVENUE, BY COUNTRY, (2019-2027) ($MN) 389
TABLE 89 REST OF THE WORLD ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, (2019-2027) ($MN) 408
TABLE 90 REST OF THE WORLD EXTREMITIES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 409
TABLE 91 REST OF THE WORLD UPPER EXTREMITIES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 410
TABLE 92 REST OF THE WORLD SPINE MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 411
TABLE 93 REST OF THE WORLD FUSION DEVICES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 412
TABLE 94 REST OF THE WORLD NON-FUSION DEVICES MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 413
TABLE 95 REST OF THE WORLD ORTHOBIOLOGICS MARKET REVENUE, BY PRODUCT TYPE, (2019-2027) ($MN) 414
TABLE 96 REST OF THE WORLD ORTHOPAEDIC DEVICES MARKET REVENUE, BY SURGERY TYPE, (2019-2027) ($MN) 415
TABLE 97 REST OF THE WORLD ORTHOPAEDIC DEVICES MARKET REVENUE, BY END-USERS (2019-2027) ($MN) 416
TABLE 98 REST OF THE WORLD ORTHOPAEDIC DEVICES MARKET REVENUE, BY COUNTRY, (2019-2027) ($MN) 422
TABLE 99 PRODUCT LAUNCH 435
TABLE 100 PRODUCT APPROVAL 440
TABLE 101 ACQUISITION 441
TABLE 102 AGREEMENTS 443
TABLE 103 OTHER DEVELOPMENTS 444
TABLE 104 B BRAUN MELSUNGEN: TOTAL REVENUE AND R&D EXPENSES (2017-2019) ($MN) 451
TABLE 105 B BRAUN MELSUNGEN: TOTAL REVENUE, BY SEGMENTS (2017-2019) ($MN) 452
TABLE 106 B BRAUN MELSUNGEN: TOTAL REVENUE, BY GEOGRAPHY (2017-2019) ($MN) 453
TABLE 107 COLFAX CORPORATION (DJO, LLC): TOTAL REVENUE AND R&D EXPENSES, (2018-2020) ($MN) 458
TABLE 108 COLFAX CORPORATION (DJO, LLC): TOTAL REVENUE, BY SEGMENTS, (2018-2020) ($MN) 459
TABLE 109 GLOBUS MEDICAL INC.: TOTAL REVENUE AND R&D EXPENSES, (2018-2020) ($MN) 464
TABLE 110 GLOBUS MEDICAL INC.: TOTAL REVENUE, BY SEGMENTS, (2018-2020) ($MN) 465
TABLE 111 GLOBUS MEDICAL, INC: TOTAL REVENUE, BY GEOGRAPHY, (2018-2020) ($MN) 466
TABLE 112 JOHNSON & JOHNSON: TOTAL REVENUE AND R&D EXPENSES, (2018 -2020) ($MN) 474
TABLE 113 JOHNSON & JOHNSON: TOTAL REVENUE, BY SEGMENTS, (2018-2020) ($MN) 475
TABLE 114 JOHNSON & JOHNSON: MEDICAL DEVICE REVENUE, BY SUB-SEGMENTS, (2018-2020) ($MN) 476
TABLE 115 JOHNSON & JOHNSON: ORTHOPAEDIC DEVICE REVENUE, BY SUB-SEGMENTS, (2018-2020) ($MN) 477
TABLE 116 JOHNSON & JOHNSON: TOTAL REVENUE, BY GEOGRAPHY, (2018-2020) ($MN) 478
TABLE 117 MEDTRONIC PLC: TOTAL REVENUE AND OPERATING EXPENSES (2019-2021) ($MN) 487
TABLE 118 MEDTRONIC PLC: TOTAL REVENUE, BY SEGMENT, (2019-2021) ($MN) 488
TABLE 119 MEDTRONIC PLC: TOTAL REVENUE, BY GEOGRAPHY, (2019-2021) ($MN) 489
TABLE 120 NUVASIVE INC.: TOTAL REVENUE AND R&D EXPENSES, (2018-2020) ($MN) 494
TABLE 121 NUVASIVE INC.: TOTAL REVENUE, BY SEGMENTS, (2018-2020) ($MN) 495
TABLE 122 NUVASIVE, INC: TOTAL REVENUE, BY GEOGRAPHY, (2018-2020) ($MN) 496
TABLE 123 SMITH & NEPHEW PLC: TOTAL REVENUE AND R&D EXPENSES, (2018-2020) ($MN) 504
TABLE 124 SMITH & NEPHEW PLC: TOTAL REVENUE, BY SEGMENTS, (2018-2020) ($MN) 505
TABLE 125 SMITH & NEPHEW PLC: ORTHOPAEDIC REVENUE, BY SUB-SEGMENTS, (2018-2020) ($MN) 506
TABLE 126 SMITH & NEPHEW PLC: SPORTS MEDICINE & ENT, BY SUB-SEGMENTS, (2018-2020) ($MN) 507
TABLE 127 SMITH & NEPHEW PLC: TOTAL REVENUE, BY GEOGRAPHY, (2018-2020) ($MN) 508
TABLE 128 STRYKER CORPORATION: TOTAL REVENUE AND R&D EXPENSES, (2018-2020) ($MN) 517
TABLE 129 STRYKER CORPORATION: TOTAL REVENUE, BY SEGMENTS, (2018-2020) ($MN) 518
TABLE 130 STRYKER CORPORATION: ORTHOPAEDICS, BY SUB-SEGMENT, (2018-2020) ($MN) 519
TABLE 131 STRYKER CORPORATION: NEUROTECHNOLOGY AND SPINE REVENUE, BY SUB-SEGMENT, (2018-2020) ($MN) 520
TABLE 132 STRYKER CORPORATION: TOTAL REVENUE, BY GEOGRAPHY, (2018-2020) ($MN) 521
TABLE 133 ZIMMER BIOMET HOLDINGS, INC: TOTAL REVENUE AND R&D EXPENSES, (2018-2020) ($MN) 532
TABLE 134 ZIMMER BIOMET HOLDINGS, INC: TOTAL REVENUE, BY SEGMENTS, (2018-2020) ($MN) 533
TABLE 135 ZIMMER BIOMET HOLDINGS, INC: TOTAL REVENUE, BY GEOGRAPHY, (2018-2020) ($MN) 534

LIST OF FIGURES
FIGURE 1 ORTHOPAEDIC DEVICES GLOBAL MARKET REVENUE, BY REGION (2019-2027) ($MN) 30
FIGURE 2 RESEARCH METHODOLOGY: ORTHOPAEDIC DEVICES GLOBAL MARKET 39
FIGURE 3 ORTHOPAEDIC DEVICES GLOBAL MARKET: TOP-DOWN AND BOTTOM-UP APPROACH 40
FIGURE 4 ORTHOPAEDIC DEVICES GLOBAL MARKET: FORECASTING MODEL 41
FIGURE 5 ORTHOPAEDIC DEVICES GLOBAL MARKET: MARKET BREAKDOWN AND DATA TRIANGULATION 42
FIGURE 6 ORTHOPAEDIC DEVICES GLOBAL MARKET SEGMENTATION 51
FIGURE 7 MARKET DYNAMICS 52
FIGURE 8 ORTHOPAEDIC DEVICES GLOBAL MARKET: PORTER'S ANALYSIS 91
FIGURE 9 ORTHOPAEDIC DEVICES: SUPPLY CHAIN ANALYSIS 99
FIGURE 10 ORTHOPAEDIC DEVICES GLOBAL MARKET: PATENT FILING BY MAJOR PLAYERS (2015-2020) 114
FIGURE 11 ORTHOPAEDIC DEVICES GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2020 (%) 119
FIGURE 12 KNEE GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2020 (%) 123
FIGURE 13 HIP GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2020 (%) 125
FIGURE 14 SPINE GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2020 (%) 127
FIGURE 15 TRAUMA GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2020 (%) 129
FIGURE 16 SPORTS MEDICINE GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2020 (%) 131
FIGURE 17 ORTHOBIOLOGICS GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2020 (%) 133
FIGURE 18 SHOULDER GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2020 (%) 135
FIGURE 19 FOOT & ANKLE GLOBAL MARKET SHARE ANALYSIS, BY KEY PLAYERS, 2020 (%) 137
FIGURE 20 KNEE ARTHROPLASTY PROCEDURAL VOLUME, BY REGION (2020 V/S 2027) (NO'S) 141
FIGURE 21 TOTAL KNEE ARTHROPLASTY PROCEDURAL VOLUME, BY REGION (2020 V/S 2027) (NO'S) 143
FIGURE 22 HIP ARTHROPLASTY PROCEDURAL VOLUME, BY REGION (2020 V/S 2027) (NO'S) 148
FIGURE 23 TOTAL HIP ARTHROPLASTY PROCEDURAL VOLUME, BY REGION (2020 V/S 2027) (NO'S) 150
FIGURE 24 SPINE ARTHROPLASTY PROCEDURAL VOLUME, BY REGION (2020 V/S 2027) (NO'S) 156
FIGURE 25 SHOULDER ARTHROPLASTY PROCEDURAL VOLUME, BY REGION (2020 V/S 2027) (NO'S) 159
FIGURE 26 PRIMARY TOTAL SHOULDER ARTHROPLASTY PROCEDURAL VOLUME, BY REGION (2020 V/S 2027) (NO'S) 161
FIGURE 27 ORTHOPAEDIC DEVICES GLOBAL MARKET SHARE, BY PRODUCT (2020 V/S 2027) (%) 187
FIGURE 28 KNEE GLOBAL MARKET SHARE, BY REGION (2020 V/S 2027) (%) 190
FIGURE 29 EXTREMITIES GLOBAL MARKET SHARE, BY PRODUCT TYPE (2020) (%) 204
FIGURE 30 SPINE GLOBAL MARKET SHARE, BY PRODUCT TYPE (2020 V/S 2027) (%) 225
FIGURE 31 FUSION GLOBAL MARKET SHARE, BY PRODUCT TYPE (2020 V/S 2027) (%) 229
FIGURE 32 NON-FUSION GLOBAL MARKET SHARE, BY PRODUCT TYPE (2020 V/S 2027) (%) 246
FIGURE 33 NON-FUSION GLOBAL MARKET SHARE, BY REGION (2020 V/S 2027) (%) 248
FIGURE 34 ARTIFICIAL DISCS GLOBAL MARKET SHARE, BY REGION (2020 V/S 2027) (%) 251
FIGURE 35 TRAUMA GLOBAL MARKET SHARE, BY REGION (2020 V/S 2027) (%) 266
FIGURE 36 ORTHOBIOLOGICS GLOBAL MARKET SHARE, BY PRODUCT TYPE (2020 V/S 2027) (%) 271
FIGURE 37 ORTHOPAEDIC DEVICES GLOBAL MARKET SHARE, BY SURGERY TYPE (2020 V/S 2027) (%) 283
FIGURE 38 OPEN SURGERY GLOBAL MARKET SHARE, BY REGION (2020 V/S 2027) (%) 286
FIGURE 39 MINIMALLY INVASIVE SURGERY GLOBAL MARKET SHARE, BY REGION (2020 V/S 2027) (%) 290
FIGURE 40 ORTHOPAEDIC DEVICES GLOBAL MARKET SHARE, BY END-USERS (2020 V/S 2027) (%) 296
FIGURE 41 ORTHOPAEDIC DEVICES GLOBAL MARKET REVENUE, BY REGION (2019-2027) ($MN), CAGR (%) 305
FIGURE 42 ORTHOPAEDIC DEVICES GLOBAL MARKET SHARE BY REGION AND MARKET REVENUE BY COUNTRY, (2020) (%) ($MN) 306
FIGURE 43 NORTH AMERICA ORTHOPAEDIC DEVICES MARKET SHARE, BY PRODUCT (2020) (%), CAGR (%) 319
FIGURE 44 NORTH AMERICA EXTREMITIES MARKET SHARE, BY PRODUCT TYPE (2020) (%) 320
FIGURE 45 NORTH AMERICA SPINE MARKET SHARE, BY PRODUCT TYPE AND FUSION, NON-FUSION DEVICES MARKET SHARE BY PRODUCT TYPE (2020 V/S 2027) (%) 321
FIGURE 46 NORTH AMERICA ORTHOBIOLOGICS MARKET SHARE, BY PRODUCT TYPE (2020 V/S 2027) (%) 322
FIGURE 47 NORTH AMERICA ORTHOPAEDIC DEVICES MARKET SHARE, BY SURGERY TYPE AND END-USERS (2020 V/S 2027) (%) 323
FIGURE 48 NORTH AMERICA ORTHOPAEDIC DEVICES MARKET SHARE, BY COUNTRY (2020 V/S 2027) (%) 325
FIGURE 49 U.S. ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 330
FIGURE 50 REST OF NORTH AMERICA ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 335
FIGURE 51 EUROPE ORTHOPAEDIC DEVICES MARKET SHARE, BY PRODUCT (2020) (%), CAGR (%) 349
FIGURE 52 EUROPE EXTREMITIES MARKET SHARE, BY PRODUCT TYPE (2020) (%) 350
FIGURE 53 EUROPE SPINE MARKET SHARE, BY PRODUCT TYPE AND FUSION, NON-FUSION DEVICES MARKET SHARE BY PRODUCT TYPE (2020 V/S 2027) (%) 351
FIGURE 54 EUROPE ORTHOBIOLOGICS MARKET SHARE, BY PRODUCT TYPE (2020 V/S 2027) (%) 352
FIGURE 55 EUROPE ORTHOPAEDIC DEVICES MARKET SHARE, BY SURGERY TYPE AND END-USERS (2020 V/S 2027) (%) 353
FIGURE 56 EUROPE ORTHOPAEDIC DEVICES MARKET SHARE, BY COUNTRY (2020 V/S 2027) (%) 355
FIGURE 57 GERMANY ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 359
FIGURE 58 FRANCE ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 362
FIGURE 59 U.K. ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 366
FIGURE 60 REST OF EUROPE ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 369
FIGURE 61 APAC ORTHOPAEDIC DEVICES MARKET SHARE, BY PRODUCT (2020) (%), CAGR (%) 384
FIGURE 62 APAC EXTREMITIES MARKET SHARE, BY PRODUCT TYPE (2020) (%) 385
FIGURE 63 APAC SPINE MARKET SHARE, BY PRODUCT TYPE AND FUSION, NON-FUSION DEVICES MARKET SHARE BY PRODUCT TYPE (2020 V/S 2027) (%) 386
FIGURE 64 APAC ORTHOBIOLOGICS MARKET SHARE, BY PRODUCT TYPE (2020 V/S 2027) (%) 387
FIGURE 65 APAC ORTHOPAEDIC DEVICES MARKET SHARE, BY SURGERY TYPE AND END-USERS (2020 V/S 2027) (%) 388
FIGURE 66 APAC ORTHOPAEDIC DEVICES MARKET SHARE, BY COUNTRY (2020 V/S 2027) (%) 390
FIGURE 67 JAPAN ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 394
FIGURE 68 INDIA ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 397
FIGURE 69 CHINA ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 400
FIGURE 70 REST OF APAC ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 404
FIGURE 71 ROW ORTHOPAEDIC DEVICES MARKET SHARE, BY PRODUCT (2020) (%), CAGR (%) 417
FIGURE 72 ROW EXTREMITIES MARKET SHARE, BY PRODUCT TYPE (2020) (%) 418
FIGURE 73 ROW SPINE MARKET SHARE, BY PRODUCT TYPE AND FUSION, NON-FUSION DEVICES MARKET SHARE BY PRODUCT TYPE (2020 V/S 2027) (%) 419
FIGURE 74 ROW ORTHOBIOLOGICS MARKET SHARE, BY PRODUCT TYPE (2020 V/S 2027) (%) 420
FIGURE 75 ROW ORTHOPAEDIC DEVICES MARKET SHARE, BY SURGERY TYPE AND END-USERS (2020 V/S 2027) (%) 421
FIGURE 76 ROW ORTHOPAEDIC DEVICES MARKET SHARE, BY COUNTRY (2020 V/S 2027) (%) 423
FIGURE 77 BRAZIL ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 426
FIGURE 78 REST OF LATIN AMERICA ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 429
FIGURE 79 MIDDLE EAST AND OTHERS ORTHOPAEDIC DEVICES MARKET REVENUE, BY PRODUCT, SURGERY TYPE AND END-USERS (2020 V/S 2027) ($MN) 432
FIGURE 80 KEY DEVELOPMENTS (2018 -2020) 434
FIGURE 81 SWOT: ARTHREX INC. 449
FIGURE 82 SWOT: B. BRAUN MELSUNGEN AG 456
FIGURE 83 SWOT: COLFAX CORPORATION (DJO, LLC) 462
FIGURE 84 SWOT: GLOBUS MEDICAL INC. 472
FIGURE 85 SWOT: JOHNSON & JOHNSON (DEPUY SYNTHES) 485
FIGURE 86 SWOT: MEDTRONIC PLC 492
FIGURE 87 SWOT: NUVASIVE INC. 502
FIGURE 88 SWOT: SMITH & NEPHEW PLC 515
FIGURE 89 SWOT: STRYKER CORPORATION 530
FIGURE 90 SWOT: ZIMMER BIOMET HOLDINGS INC 545

Companies Mentioned
• ARTHREX INC.
• B. BRAUN MELSUNGEN AG
• COLFAX CORPORATION (DJO, LLC)
• GLOBUS MEDICAL INC.
• JOHNSON & JOHNSON (DEPUY SYNTHES)
• MEDTRONIC PLC
• NUVASIVE INC.
• SMITH & NEPHEW PLC
• STRYKER CORPORATION
• ZIMMER BIOMET HOLDINGS INC
• LIST OF COMPANIES MENTIONED IN THE REPORT
• ACUITIVE TECHNOLOGIES
• ACUMED LLC
• ADDITIVE ORTHOPAEDICS, LLC
• ADLER ORTHO S.R.L
• AK MEDICAL
• ALLOPLUS GMBH
• ALPHATEC HOLDINGS INC
• AMPLITUDE SURGICAL
• ANCHOR ORTHOPAEDICS XT INC
• ARAN BIOMEDICAL
• ARTHREX INC.
• ASTURA MEDICAL
• ATLAS SURGICAL PVT
• ATRO MEDICAL, INC.
• AUXEIN MEDICAL
• B. BRAUN MELSUNGEN AG
• BIOMED HEALTH TECH
• BIOREZ INC.
• BONE THERAPEUTICS
• BONEUNION (XIAMEN) MEDICAL DEVICES CO. LTD
• CARBOFIX ORTHOPAEDIC LTD
• CAREVATURE MEDICAL LTD.
• CARPENTER TECHNOLOGY CORPORATION
• CARTIHEAL LTD
• CENTINEL SPINE, LLC
• CHANGZHOU MEDITECH TRADING CO., LTD.
• COLFAX CORPORATION
• COLLAGEN MATRIX, INC.
• CONMED CORPORATION
• CONSENSUS ORTHOPEDICS INC.
• CORIN GROUP
• CURVAFIX INC.
• DEDIENNE SANTÉ
• EUROSILICONE SAS
• EXACTECH INC
• GENEREX BIOTECHNOLOGY CORPORATION
• GUANGZHOU SAILONG ADDITIVE MANUFACTURING CO., LTD.
• HISTOGEN INC.
• IMEN IJAZ MEDICAL ENGINEERING
• IN2BONES GLOBAL, INC
• INNOVASIS, INC.
• INNOVATION ORTHO LINE LTD
• INNOVATIVE DESIGN ORTHOPAEDICS
• INTEGRA LIFESCIENCES
• INTRINSIC THERAPEUTICS INC.
• JOHNSON & JOHNSON
• KELLOGG'S RESEARCH LABS
• LIMACORPORATE
• MAATHYS MEDICAL
• MATORTHO LIMITED
• MEDACTA INTERNATIONAL SA
• MEDARTIS AG
• MEDICALEX S A
• MEDTRONIC PLC
• MERETE
• MERIL LIFE SCIENCES PVT. LTD
• MICROPORT SCIENTIFIC CORPORATION
• NEO MEDICAL SA
• NEURO FRANCE IMPLANTS
• NEXXT SPINE, LLC
• NUVASIVE INC.
• OLYMPUS CORPORATION
• ORTHO CONSULTING GROUP HOLDINGS
• ORTHO REGENERATIVE TECHNOLOGIES INC.
• ORTHOFIX MEDICAL INC.
• PAONAN BIOTECH CO., LTD (BIOMECH)
• PREMIA SPINE
• REGENEXX CORPORATE
• REM SYSTEMS
• RTI SURGICAL
• SEASPINE HOLDINGS CORPORATION
• SHAKTI ORTHOPAEDIC INDUSTRIES (P) LTD
• SHOWA IKA KOHGYO CO., LTD.
• SIEMENS HEALTHINEERS
• SIGMA SURGICALS PVT. LTD.
• SIGNUS MEDIZINTECHNIK GMBH
• SIMPLIFY MEDICAL, INC.
• SMITH & NEPHEW PLC
• SPINAL ELEMENTS INC.
• STRYKER CORPORATION
• SURGIVAL INTERNATIONAL
• SYNERGY DISC REPLACEMENT INC.
• TINAVI
• TYBER MEDICAL, LLC,
• ULRICH MEDICAL USA, INC.
• WALDEMAR LINK GMBH & CO. KG
• WISHBONE MEDICAL
• ZIMMER AND BIOMET HOLDINGS INC
• Z-MEDICAL GMBH + CO. KG