Table of Contents
Table of Contents 2
Introduction 7
Metastatic Colorectal Cancer Overview 8
Therapeutics Development 9
Metastatic Colorectal Cancer - Therapeutics under Development by Companies 11
Metastatic Colorectal Cancer - Therapeutics under Investigation by Universities/Institutes 18
Metastatic Colorectal Cancer - Pipeline Products Glance 19
Metastatic Colorectal Cancer - Products under Development by Companies 23
Metastatic Colorectal Cancer - Products under Investigation by Universities/Institutes 32
Metastatic Colorectal Cancer - Companies Involved in Therapeutics Development 33
Metastatic Colorectal Cancer - Therapeutics Assessment 122
Drug Profiles 149
Metastatic Colorectal Cancer - Dormant Projects 682
Metastatic Colorectal Cancer - Discontinued Products 692
Metastatic Colorectal Cancer - Product Development Milestones 695
Appendix 710


List of Tables

Number of Products under Development for Metastatic Colorectal Cancer, H2 2016 25
Number of Products under Development for Metastatic Colorectal Cancer - Comparative Analysis, H2 2016 26
Number of Products under Development by Companies, H2 2016 27
Number of Products under Development by Companies, H2 2016 (Contd..1) 28
Number of Products under Development by Companies, H2 2016 (Contd..2) 29
Number of Products under Development by Companies, H2 2016 (Contd..3) 30
Number of Products under Development by Companies, H2 2016 (Contd..4) 31
Number of Products under Development by Companies, H2 2016 (Contd..5) 32
Number of Products under Development by Companies, H2 2016 (Contd..6) 33
Number of Products under Investigation by Universities/Institutes, H2 2016 34
Comparative Analysis by Late Stage Development, H2 2016 35
Comparative Analysis by Clinical Stage Development, H2 2016 36
Comparative Analysis by Early Stage Development, H2 2016 37
Comparative Analysis by Unknown Stage Development, H2 2016 38
Products under Development by Companies, H2 2016 39
Products under Development by Companies, H2 2016 (Contd..1) 40
Products under Development by Companies, H2 2016 (Contd..2) 41
Products under Development by Companies, H2 2016 (Contd..3) 42
Products under Development by Companies, H2 2016 (Contd..4) 43
Products under Development by Companies, H2 2016 (Contd..5) 44
Products under Development by Companies, H2 2016 (Contd..6) 45
Products under Development by Companies, H2 2016 (Contd..7) 46
Products under Development by Companies, H2 2016 (Contd..8) 47
Products under Investigation by Universities/Institutes, H2 2016 48
Metastatic Colorectal Cancer - Pipeline by 3SBio Inc, H2 2016 49
Metastatic Colorectal Cancer - Pipeline by AB Science SA, H2 2016 50
Metastatic Colorectal Cancer - Pipeline by AbbVie Inc, H2 2016 51
Metastatic Colorectal Cancer - Pipeline by Advenchen Laboratories LLC, H2 2016 52
Metastatic Colorectal Cancer - Pipeline by Alchemia Ltd, H2 2016 53
Metastatic Colorectal Cancer - Pipeline by Apexigen Inc, H2 2016 54
Metastatic Colorectal Cancer - Pipeline by ArQule Inc, H2 2016 55
Metastatic Colorectal Cancer - Pipeline by Array BioPharma Inc, H2 2016 56
Metastatic Colorectal Cancer - Pipeline by Asana BioSciences LLC, H2 2016 57
Metastatic Colorectal Cancer - Pipeline by Astex Pharmaceuticals Inc, H2 2016 58
Metastatic Colorectal Cancer - Pipeline by AstraZeneca Plc, H2 2016 59
Metastatic Colorectal Cancer - Pipeline by Bavarian Nordic A/S, H2 2016 60
Metastatic Colorectal Cancer - Pipeline by Bayer AG, H2 2016 61
Metastatic Colorectal Cancer - Pipeline by Biocon Ltd, H2 2016 62
Metastatic Colorectal Cancer - Pipeline by Bionomics Ltd, H2 2016 63
Metastatic Colorectal Cancer - Pipeline by Bionovis SA, H2 2016 64
Metastatic Colorectal Cancer - Pipeline by Biothera Pharmaceutical Inc, H2 2016 65
Metastatic Colorectal Cancer - Pipeline by Boehringer Ingelheim GmbH, H2 2016 66
Metastatic Colorectal Cancer - Pipeline by Boston Biomedical Inc, H2 2016 67
Metastatic Colorectal Cancer - Pipeline by Bristol-Myers Squibb Company, H2 2016 68
Metastatic Colorectal Cancer - Pipeline by Burzynski Research Institute Inc, H2 2016 69
Metastatic Colorectal Cancer - Pipeline by Celgene Corp, H2 2016 70
Metastatic Colorectal Cancer - Pipeline by Celltrion Inc, H2 2016 71
Metastatic Colorectal Cancer - Pipeline by Cipla Ltd, H2 2016 72
Metastatic Colorectal Cancer - Pipeline by Coherus BioSciences Inc, H2 2016 73
Metastatic Colorectal Cancer - Pipeline by Cornerstone Pharmaceuticals Inc, H2 2016 74
Metastatic Colorectal Cancer - Pipeline by DanDrit Biotech A/S, H2 2016 75
Metastatic Colorectal Cancer - Pipeline by Dr. Reddy's Laboratories Ltd, H2 2016 76
Metastatic Colorectal Cancer - Pipeline by EirGenix Inc., H2 2016 77
Metastatic Colorectal Cancer - Pipeline by Eisai Co Ltd, H2 2016 78
Metastatic Colorectal Cancer - Pipeline by Eli Lilly and Company, H2 2016 79
Metastatic Colorectal Cancer - Pipeline by EnGeneIC Ltd, H2 2016 80
Metastatic Colorectal Cancer - Pipeline by Etubics Corp, H2 2016 81
Metastatic Colorectal Cancer - Pipeline by Exelixis Inc, H2 2016 82
Metastatic Colorectal Cancer - Pipeline by F. Hoffmann-La Roche Ltd, H2 2016 83
Metastatic Colorectal Cancer - Pipeline by Gene Techno Science Co Ltd, H2 2016 84
Metastatic Colorectal Cancer - Pipeline by Genor BioPharma Co Ltd, H2 2016 85
Metastatic Colorectal Cancer - Pipeline by Genzyme Corp, H2 2016 86
Metastatic Colorectal Cancer - Pipeline by Gilead Sciences Inc, H2 2016 87
Metastatic Colorectal Cancer - Pipeline by GlaxoSmithKline Plc, H2 2016 88
Metastatic Colorectal Cancer - Pipeline by Glycotope GmbH, H2 2016 89
Metastatic Colorectal Cancer - Pipeline by Hemispherx Biopharma Inc, H2 2016 90
Metastatic Colorectal Cancer - Pipeline by Hutchison MediPharma Ltd, H2 2016 91
Metastatic Colorectal Cancer - Pipeline by Ignyta Inc, H2 2016 92
Metastatic Colorectal Cancer - Pipeline by Immodulon Therapeutics Ltd, H2 2016 93
Metastatic Colorectal Cancer - Pipeline by Immunomedics Inc, H2 2016 94
Metastatic Colorectal Cancer - Pipeline by Immunovative Therapies Ltd, H2 2016 95
Metastatic Colorectal Cancer - Pipeline by Karyopharm Therapeutics Inc, H2 2016 96
Metastatic Colorectal Cancer - Pipeline by Mabion SA, H2 2016 97
Metastatic Colorectal Cancer - Pipeline by Mabtech Limited, H2 2016 98
Metastatic Colorectal Cancer - Pipeline by mAbxience SA, H2 2016 99
Metastatic Colorectal Cancer - Pipeline by MacroGenics Inc, H2 2016 100
Metastatic Colorectal Cancer - Pipeline by MedImmune LLC, H2 2016 101
Metastatic Colorectal Cancer - Pipeline by Merck & Co Inc, H2 2016 102
Metastatic Colorectal Cancer - Pipeline by Merck KGaA, H2 2016 103
Metastatic Colorectal Cancer - Pipeline by Merrimack Pharmaceuticals Inc, H2 2016 104
Metastatic Colorectal Cancer - Pipeline by Merus NV, H2 2016 105
Metastatic Colorectal Cancer - Pipeline by MolMed SpA, H2 2016 106
Metastatic Colorectal Cancer - Pipeline by Mologen AG, H2 2016 107
Metastatic Colorectal Cancer - Pipeline by Morphotek Inc, H2 2016 108
Metastatic Colorectal Cancer - Pipeline by Mycenax Biotech Inc, H2 2016 109
Metastatic Colorectal Cancer - Pipeline by Natco Pharma Ltd, H2 2016 110
Metastatic Colorectal Cancer - Pipeline by Nektar Therapeutics, H2 2016 111
Metastatic Colorectal Cancer - Pipeline by Nippon Kayaku Co Ltd, H2 2016 112
Metastatic Colorectal Cancer - Pipeline by Northwest Biotherapeutics Inc, H2 2016 113
Metastatic Colorectal Cancer - Pipeline by Novartis AG, H2 2016 114
Metastatic Colorectal Cancer - Pipeline by OBI Pharma Inc, H2 2016 115
Metastatic Colorectal Cancer - Pipeline by Oncobiologics Inc, H2 2016 116
Metastatic Colorectal Cancer - Pipeline by Oncolytics Biotech Inc, H2 2016 117
Metastatic Colorectal Cancer - Pipeline by OncoMed Pharmaceuticals Inc, H2 2016 118
Metastatic Colorectal Cancer - Pipeline by Ono Pharmaceutical Co Ltd, H2 2016 119
Metastatic Colorectal Cancer - Pipeline by Pfizer Inc, H2 2016 120
Metastatic Colorectal Cancer - Pipeline by Pharma Mar SA, H2 2016 121
Metastatic Colorectal Cancer - Pipeline by Pivot Pharmaceuticals Inc, H2 2016 122
Metastatic Colorectal Cancer - Pipeline by Precision Biologics Inc, H2 2016 123
Metastatic Colorectal Cancer - Pipeline by PsiOxus Therapeutics Ltd, H2 2016 124
Metastatic Colorectal Cancer - Pipeline by R Pharm, H2 2016 125
Metastatic Colorectal Cancer - Pipeline by Regeneron Pharmaceuticals Inc, H2 2016 126
Metastatic Colorectal Cancer - Pipeline by Richter Gedeon Nyrt, H2 2016 127
Metastatic Colorectal Cancer - Pipeline by Shanghai Henlius Biotech Co., Ltd., H2 2016 128
Metastatic Colorectal Cancer - Pipeline by Shire Plc, H2 2016 129
Metastatic Colorectal Cancer - Pipeline by Sillajen Biotherapeutics, H2 2016 130
Metastatic Colorectal Cancer - Pipeline by Symphogen A/S, H2 2016 131
Metastatic Colorectal Cancer - Pipeline by Synermore Biologics Co Ltd, H2 2016 132
Metastatic Colorectal Cancer - Pipeline by Taiho Pharmaceutical Co Ltd, H2 2016 133
Metastatic Colorectal Cancer - Pipeline by TaiwanJ Pharmaceuticals Co Ltd, H2 2016 134
Metastatic Colorectal Cancer - Pipeline by Tocagen Inc, H2 2016 135
Metastatic Colorectal Cancer - Pipeline by Vaximm AG, H2 2016 136
Metastatic Colorectal Cancer - Pipeline by XBiotech Inc, H2 2016 137
Assessment by Monotherapy Products, H2 2016 138
Assessment by Combination Products, H2 2016 139
Number of Products by Stage and Target, H2 2016 141
Number of Products by Stage and Mechanism of Action, H2 2016 151
Number of Products by Stage and Route of Administration, H2 2016 162
Number of Products by Stage and Molecule Type, H2 2016 164
Metastatic Colorectal Cancer - Dormant Projects, H2 2016 698
Metastatic Colorectal Cancer - Dormant Projects (Contd..1), H2 2016 699
Metastatic Colorectal Cancer - Dormant Projects (Contd..2), H2 2016 700
Metastatic Colorectal Cancer - Dormant Projects (Contd..3), H2 2016 701
Metastatic Colorectal Cancer - Dormant Projects (Contd..4), H2 2016 702
Metastatic Colorectal Cancer - Dormant Projects (Contd..5), H2 2016 703
Metastatic Colorectal Cancer - Dormant Projects (Contd..6), H2 2016 704
Metastatic Colorectal Cancer - Dormant Projects (Contd..7), H2 2016 705
Metastatic Colorectal Cancer - Dormant Projects (Contd..8), H2 2016 706
Metastatic Colorectal Cancer - Dormant Projects (Contd..9), H2 2016 707
Metastatic Colorectal Cancer - Discontinued Products, H2 2016 708
Metastatic Colorectal Cancer - Discontinued Products (Contd..1), H2 2016 709
Metastatic Colorectal Cancer - Discontinued Products (Contd..2), H2 2016 710

List of Figures
Number of Products under Development for Metastatic Colorectal Cancer, H2 2016 25
Number of Products under Development for Metastatic Colorectal Cancer - Comparative Analysis, H2 2016 26
Number of Products under Development by Companies, H2 2016 27
Number of Products under Investigation by Universities/Institutes, H2 2016 34
Comparative Analysis by Late Stage Development, H2 2016 35
Comparative Analysis by Clinical Stage Development, H2 2016 36
Comparative Analysis by Early Stage Products, H2 2016 37
Assessment by Monotherapy Products, H2 2016 138
Assessment by Combination Products, H2 2016 139
Number of Products by Top 10 Targets, H2 2016 140
Number of Products by Stage and Top 10 Targets, H2 2016 140
Number of Products by Top 10 Mechanism of Actions, H2 2016 150
Number of Products by Stage and Top 10 Mechanism of Actions, H2 2016 150
Number of Products by Top 10 Routes of Administration, H2 2016 161
Number of Products by Stage and Top 10 Routes of Administration, H2 2016 161
Number of Products by Top 10 Molecule Types, H2 2016 163
Number of Products by Stage and Top 10 Molecule Types, H2 2016 163