About 800 reports

  • GASTROINTESTINAL THERAPEUTICS MARKET, GLOBAL, CLINICAL PROGRAM SIZE BY
  • GASTROINTESTINAL THERAPEUTICS MARKET, GLOBAL, CLINICAL TRIAL DURATION BY
  • Clinical Trial
  • World
  • Market Size
  • AstraZeneca PLC
  • Takeda Pharmaceutical Company Limited

The MTD was not reached during this phase of the trial, and the majority of adverse events were mild or moderate gastrointestinal or hematological toxicities.

  • Clinical Trial
  • Forecast
  • Novartis AG
  • Pfizer Inc.
  • Roche Group

Minor AEs such as stomatitis, headaches, fatigue and gastrointestinal problems such as nausea and vomiting may occur when using Metolate.

  • Clinical Trial
  • World
  • AbbVie Inc.
  • Allergan plc
  • Amgen Inc.
  • Pipeline Landscape Assessment

Gastrointestinal Cancer Research; ##(##): ##-## Mayo Clinic (2014).

  • Clinical Trial
  • World
  • AbbVie Inc.
  • Janssen Biotech, Inc.
  • Johnson & Johnson

As such, non-selective COX inhibitors typically produce COX-## inhibitory gastrointestinal (GI) side effects, including gastric ulceration, bleeding and perforation.

  • Clinical Trial
  • World
  • Market Size
  • Allergan plc
  • Amgen Inc.
  • Pharmaceutical Industry, Clinical Trial Failure Rates in Phase I by Therapy Area,
  • Pharmaceutical Industry, Clinical Trial Duration in Phase II by Therapy Area, 2006-

Phase I failure rates ranged broadly from ##% in immunology and ##% in gastrointestinal disorders to ##% in musculoskeletal disorders.

  • Clinical Trial
  • Pharmaceutical
  • Therapy
  • Europe
  • Market Size

This method avoids the gastrointestinal tract and leads to more rapid effects, compared to orally administered levodopa.

  • Clinical Trial
  • World
  • Biogen Idec Inc.
  • Novartis AG
  • Roche Group

Dietary factors have a substantial influence on the risk of cancers of the gastrointestinal tract.

  • Clinical Trial
  • World
  • Market Size
  • Juno Therapeutics Inc.
  • Merck & Co., Inc.

When gastrointestinal AEs were reported their intensity was much lower than with oxycodone.

  • Clinical Trial
  • World
  • Amgen Inc.
  • Daiichi Sankyo Company
  • Eli Lilly & Co.

As previously outlined, Xenical is a gastrointestinal lipase inhibitor that acts specifically in the lumen of the stomach and small intestine.

  • Clinical Trial
  • World
  • Eli Lilly & Co.
  • Merck & Co., Inc.
  • Novo Nordisk Group

AS CF IS A MULTI-SYSTEM DISEASE, EVEN IF THE LUNG TRANSPLANT IS SUCCESSFUL, PANCREATIC, GASTROINTESTINAL AND REPRODUCTIVE PROBLEMS WILL REMAIN.

  • Clinical Trial
  • World
  • Market Size
  • Astellas Pharma Inc.
  • AstraZeneca PLC

Gastrointestinal Cancer Research; ##(##): ##-## Hurwitz H, et al. (2004).

  • Cancer
  • Clinical Trial
  • World
  • Market Size
  • Merck & Co., Inc.
  • Clinical Trial
  • World
  • Adverum Biotechnologies, Inc.
  • Alcon, Inc.
  • Allergan plc

It is also in development within the gastrointestinal disease area.

  • Clinical Trial
  • World
  • Market Size
  • Celgene Corporation
  • Novartis AG

As CF is a multi-system disease, even if the lung transplant is successful, pancreatic, gastrointestinal and reproductive problems will remain.

  • Clinical Trial
  • World
  • Market Size
  • AstraZeneca PLC
  • GlaxoSmithKline plc

In contrast, Tykerb (lapatinib), which also targets HER##, has a very low associated incidence of cardiac AEs and is instead more frequently associated with skin and gastrointestinal events.

  • Clinical Trial
  • World
  • Market Size
  • Bristol-Myers Squibb Company
  • Novartis AG

Minor AEs such as stomatitis, headaches, fatigue and gastrointestinal problems such as nausea and vomiting may occur when using methotrexate.

  • Clinical Trial
  • Dermatology
  • World
  • Market Size
  • Biologics, Inc.

Patients may develop gastrointestinal perforations, in which case treatment is stopped immediately.

  • Clinical Trial
  • AstraZeneca PLC
  • Eli Lilly & Co.
  • Novartis AG
  • Roche Group

All treatment regimens were well tolerated, with a similar incidence of upper gastrointestinal (GI) AEs.

  • Clinical Trial
  • World
  • Market Size
  • Amgen Inc.
  • Merck & Co., Inc.

Heparin is given intravenously due to poor gastrointestinal tract absorbability.

  • Clinical Trial
  • World
  • Market Size
  • Novartis AG
  • Sanofi S.A.

FIGURE ##: ANTIBACTERIAL DRUG MARKET, GLOBAL, OVERALL PHARMACEUTICAL INDUSTRY PIPELINE BY Metabolicdisorders Oncology Immunology Infectiousdisease Centralnervoussystem Respiratory Cardiovascular Ophthalmology Gastrointestinal Bacterialinfections Dermatology Geneticdisorders Musculoskeletald

  • Anti-Infective
  • Antibiotic Resistance
  • Clinical Trial
  • Infectious Disease
  • Therapy

Gastrointestinal events such as nausea and diarrhea occurred most frequently.

  • Clinical Trial
  • AstraZeneca PLC
  • Merck & Co., Inc.
  • Novo Nordisk Group
  • Sanofi S.A.

Biologics are susceptible to metabolism in the gastrointestinal tract and lack permeability, which collectively leads to poor bioavailability.

  • Clinical Trial
  • Asia
  • World
  • Market Size
  • Galapagos NV

Advances in the treatment of gastrointestinal stromal tumours.

  • Clinical Trial
  • World
  • Astellas Pharma Inc.
  • AstraZeneca PLC
  • Pfizer Inc.

NOD (DRAG) mice sustain the Complex Vertebrate Life Cycle of Plasmodium Falciparum Malaria Complex Interactions Among Diet, Gastrointestinal Transit, and Gut Microbiota in Humanized Mice Model of Ischemic Stroke Potential Limitations of the NSG Humanized Mouse as a Model System to Optimize

  • Clinical Trial
  • World
  • genOway SA
  • Horizon Discovery
  • Taconic Biosciences, Inc.
  • Clinical Trials by E7 Countries: Proportion of Functional (Non Ulcer) Dyspepsia to Gastrointestinal...
  • Clinical Trials by G7 Countries: Proportion of Functional (Non Ulcer) Dyspepsia to Gastrointestinal...
  • Clinical Trial
  • World
  • Actavis plc
  • Astellas Pharma Inc.
  • Zeria Pharmaceutical Co., Ltd.

Gastrointestinal Endoscopy; ##(##): ##-## Chung HC, et al. (2016).

  • Clinical Trial
  • World
  • Market Size
  • AstraZeneca PLC
  • Roche Group

However, because the drug is associated with severe adverse reactions, it carries a boxed warning for gastrointestinal (GI) perforations, surgery, wound-healing complications, and hemorrhage.

  • Clinical Trial
  • Forecast
  • Novartis AG
  • Pfizer Inc.
  • Roche Group
  • Proportion of Eosinophilic Esophagitis to Gastrointestinal Clinical Trials, G7 Countries...
  • Clinical Trials by G7 Countries: Proportion of Eosinophilic Esophagitis to Gastrointestinal...
  • Clinical Trial
  • World
  • GlaxoSmithKline plc
  • Regeneron Pharmaceuticals, Inc.
  • Sanofi S.A.

Gastrointestinal events such as nausea and diarrhea occurred most frequently.

  • Clinical Trial
  • World
  • Eli Lilly & Co.
  • Novo Nordisk Group
  • Sanofi S.A.