About 900 reports

  • GASTROINTESTINAL THERAPEUTICS MARKET, GLOBAL, CLINICAL PROGRAM SIZE BY
  • GASTROINTESTINAL THERAPEUTICS MARKET, GLOBAL, CLINICAL TRIAL DURATION BY
  • Clinical Research
  • World
  • Market Size
  • AstraZeneca PLC
  • Takeda Pharmaceutical Company Limited

The MTD was not reached during this phase of the trial, and the majority of adverse events were mild or moderate gastrointestinal or hematological toxicities.

  • Clinical Research
  • Forecast
  • Novartis AG
  • Pfizer Inc.
  • Roche Group

Minor AEs such as stomatitis, headaches, fatigue and gastrointestinal problems such as nausea and vomiting may occur when using Metolate.

  • Clinical Research
  • World
  • AbbVie Inc.
  • Allergan plc
  • Amgen Inc.
  • Pipeline Landscape Assessment

Gastrointestinal Cancer Research; ##(##): ##-## Mayo Clinic (2014).

  • Clinical Research
  • World
  • AbbVie Inc.
  • Janssen Biotech, Inc.
  • Johnson & Johnson

As such, non-selective COX inhibitors typically produce COX-## inhibitory gastrointestinal (GI) side effects, including gastric ulceration, bleeding and perforation.

  • Clinical Research
  • World
  • Market Size
  • Allergan plc
  • Amgen Inc.
  • Pharmaceutical Industry, Clinical Trial Failure Rates in Phase I by Therapy Area,
  • Pharmaceutical Industry, Clinical Trial Duration in Phase II by Therapy Area, 2006-

Phase I failure rates ranged broadly from ##% in immunology and ##% in gastrointestinal disorders to ##% in musculoskeletal disorders.

  • Clinical Research
  • Pharmaceutical
  • Therapy
  • Europe
  • Market Size

This method avoids the gastrointestinal tract and leads to more rapid effects, compared to orally administered levodopa.

  • Clinical Research
  • World
  • Biogen Idec Inc.
  • Novartis AG
  • Roche Group

Dietary factors have a substantial influence on the risk of cancers of the gastrointestinal tract.

  • Clinical Research
  • World
  • Market Size
  • Juno Therapeutics Inc.
  • Merck & Co., Inc.

When gastrointestinal AEs were reported their intensity was much lower than with oxycodone.

  • Clinical Research
  • World
  • Amgen Inc.
  • Daiichi Sankyo Company
  • Eli Lilly & Co.

As previously outlined, Xenical is a gastrointestinal lipase inhibitor that acts specifically in the lumen of the stomach and small intestine.

  • Clinical Research
  • World
  • Eli Lilly & Co.
  • Merck & Co., Inc.
  • Novo Nordisk Group

AS CF IS A MULTI-SYSTEM DISEASE, EVEN IF THE LUNG TRANSPLANT IS SUCCESSFUL, PANCREATIC, GASTROINTESTINAL AND REPRODUCTIVE PROBLEMS WILL REMAIN.

  • Clinical Research
  • World
  • Market Size
  • Astellas Pharma Inc.
  • AstraZeneca PLC

Gastrointestinal Cancer Research; ##(##): ##-## Hurwitz H, et al. (2004).

  • Cancer
  • Clinical Research
  • World
  • Market Size
  • Merck & Co., Inc.
  • Clinical Research
  • World
  • Adverum Biotechnologies, Inc.
  • Alcon, Inc.
  • Allergan plc

It is also in development within the gastrointestinal disease area.

  • Clinical Research
  • World
  • Market Size
  • Celgene Corporation
  • Novartis AG

As CF is a multi-system disease, even if the lung transplant is successful, pancreatic, gastrointestinal and reproductive problems will remain.

  • Clinical Research
  • World
  • Market Size
  • AstraZeneca PLC
  • GlaxoSmithKline plc

In contrast, Tykerb (lapatinib), which also targets HER##, has a very low associated incidence of cardiac AEs and is instead more frequently associated with skin and gastrointestinal events.

  • Clinical Research
  • World
  • Market Size
  • Bristol-Myers Squibb Company
  • Novartis AG

Minor AEs such as stomatitis, headaches, fatigue and gastrointestinal problems such as nausea and vomiting may occur when using methotrexate.

  • Clinical Research
  • World
  • Market Size
  • Amgen Inc.
  • Biologics, Inc.

All treatment regimens were well tolerated, with a similar incidence of upper gastrointestinal (GI) AEs.

  • Clinical Research
  • World
  • Market Size
  • Amgen Inc.
  • Merck & Co., Inc.

Patients may develop gastrointestinal perforations, in which case treatment is stopped immediately.

  • Clinical Research
  • AstraZeneca PLC
  • Eli Lilly & Co.
  • Novartis AG
  • Roche Group

Heparin is given intravenously due to poor gastrointestinal tract absorbability.

  • Clinical Research
  • World
  • Market Size
  • Novartis AG
  • Sanofi S.A.

FIGURE ##: ANTIBACTERIAL DRUG MARKET, GLOBAL, OVERALL PHARMACEUTICAL INDUSTRY PIPELINE BY Metabolicdisorders Oncology Immunology Infectiousdisease Centralnervoussystem Respiratory Cardiovascular Ophthalmology Gastrointestinal Bacterialinfections Dermatology Geneticdisorders Musculoskeletald

  • Antibiotic Resistance
  • Clinical Research
  • World
  • Merck & Co., Inc.
  • Pfizer Inc.

Gastrointestinal events such as nausea and diarrhea occurred most frequently.

  • Clinical Research
  • AstraZeneca PLC
  • Merck & Co., Inc.
  • Novo Nordisk Group
  • Sanofi S.A.

Biologics are susceptible to metabolism in the gastrointestinal tract and lack permeability, which collectively leads to poor bioavailability.

  • Clinical Research
  • Asia
  • World
  • Market Size
  • Galapagos NV

Advances in the treatment of gastrointestinal stromal tumours.

  • Clinical Research
  • World
  • Astellas Pharma Inc.
  • AstraZeneca PLC
  • Pfizer Inc.

NOD (DRAG) mice sustain the Complex Vertebrate Life Cycle of Plasmodium Falciparum Malaria Complex Interactions Among Diet, Gastrointestinal Transit, and Gut Microbiota in Humanized Mice Model of Ischemic Stroke Potential Limitations of the NSG Humanized Mouse as a Model System to Optimize

  • Clinical Research
  • World
  • genOway SA
  • Horizon Discovery
  • Taconic Biosciences, Inc.
  • Clinical Trials by E7 Countries: Proportion of Functional (Non Ulcer) Dyspepsia to Gastrointestinal...
  • Clinical Trials by G7 Countries: Proportion of Functional (Non Ulcer) Dyspepsia to Gastrointestinal...
  • Clinical Research
  • World
  • Actavis plc
  • Astellas Pharma Inc.
  • Zeria Pharmaceutical Co., Ltd.

Gastrointestinal Endoscopy; ##(##): ##-## Chung HC, et al. (2016).

  • Clinical Research
  • World
  • Market Size
  • AstraZeneca PLC
  • Roche Group

However, because the drug is associated with severe adverse reactions, it carries a boxed warning for gastrointestinal (GI) perforations, surgery, wound-healing complications, and hemorrhage.

  • Clinical Research
  • Forecast
  • Novartis AG
  • Pfizer Inc.
  • Roche Group
  • Proportion of Eosinophilic Esophagitis to Gastrointestinal Clinical Trials, G7 Countries...
  • Clinical Trials by G7 Countries: Proportion of Eosinophilic Esophagitis to Gastrointestinal...
  • Clinical Research
  • World
  • GlaxoSmithKline plc
  • Regeneron Pharmaceuticals, Inc.
  • Sanofi S.A.

Gastrointestinal events such as nausea and diarrhea occurred most frequently.

  • Clinical Research
  • World
  • Eli Lilly & Co.
  • Novo Nordisk Group
  • Sanofi S.A.