34 reports

Alzumab is an anti-CD## monoclonal antibody.

  • Autoimmune Disease
  • Monoclonal Antibody
  • Therapy
  • AbbVie Inc.
  • AstraZeneca PLC
  • tremelimumab

Distinct PD-L## binding characteristics of therapeutic monoclonal antibody durvalumab.

  • Breast Cancer
  • Monoclonal Antibody
  • Targeted Therapy
  • Therapy
  • AstraZeneca PLC

THESE TWO THERAPIES ARE MONOCLONAL ANTIBODY (MAB) PRODUCTS THAT TARGET INTERLEUKIN RECEPTORS, AND TYPIFY THE GROWING PROMINENCE OF MABS IN THE TREATMENT OF RESPIRATORY DISEASES.

  • Monoclonal Antibody
  • Pharmaceutical
  • Respiratory Disease
  • Therapy
  • AstraZeneca PLC

Monoclonal antibodies (mAbs) are the newest class of drugs, predominately used in the treatment of psoriasis.

  • Dermatological Condition
  • Dermatology
  • Monoclonal Antibody
  • Therapy
  • AstraZeneca PLC

CANADIAN KEY OPINION LEADER MOST OF THE CURRENT PHASE III REGISTRATIONAL TRIALS THAT ARE INVESTIGATING COMBINATION THERAPIES INVOLVE AT LEAST ONE ANTI-CD## MONOCLONAL ANTIBODY.

  • Immunotherapy
  • Monoclonal Antibody
  • Therapy
  • Market Size
  • AstraZeneca PLC
  • Papillary Pipeline Drug Molecules
  • V. Advanced/Stage IV/Metastatic RCC

Twelve are monoclonal antibody including two antibody-drug conjugates.

  • Cancer
  • Monoclonal Antibody
  • Renal Cancer
  • Therapy
  • AstraZeneca PLC

Riken LY-## LYC-## LYC-## MaaT-## melittin menadione sodium bisulfite mesalamine MGL-## Monoclonal Antibodies to Antagonize Metallothioneins for Ulcerative Colitis and Crohn' s Disease Monoclonal Antibodies to Antagonize TGF-Beta Receptor Type-

  • Gastrointestinal Drug
  • Monoclonal Antibody
  • Pharmaceutical
  • Therapy
  • AstraZeneca PLC

s PD-## antibody Keytruda.

  • Cancer
  • Chemotherapy
  • Monoclonal Antibody
  • Therapy
  • AstraZeneca PLC
  • ASTRAZENECA - BENRALIZUMAB

FIGURE ##-##: MONOCLONAL ANTIBODIES IN CANCER TREATMENT, OPDIVO PERFORMANCE VS.

  • Lymphoma
  • Monoclonal Antibody
  • Targeted Therapy
  • Therapy
  • AstraZeneca PLC
  • Pipeline Analysis

Monoclonal antibodies have a strong presence in the Preclinical, Phase I, Phase II and Phase III stages of development.

  • Monoclonal Antibody
  • Therapy
  • Market Size
  • AstraZeneca PLC
  • Boehringer Ingelheim GmbH
  • varlilumab

Herceptin is the gold standard monoclonal antibody (mAb) for the treatment of HER##positive disease, and is prescribed in nearly all settings.

  • Breast Cancer
  • Monoclonal Antibody
  • Targeted Therapy
  • Therapy
  • AstraZeneca PLC

Relationship between PD-L## expression and clinical outcomes in patients with advanced gastric cancer treated with the anti-PD-## monoclonal antibody pembrolizumab (MK-##) in KEYNOTE-##.

  • Gastric Cancer
  • Monoclonal Antibody
  • Therapy
  • AstraZeneca PLC
  • Roche Group

Avastin is a recombinant, humanized, monoclonal immunoglobulin (IgG) ## antibody developed by Roche.

  • Lung Cancer
  • Monoclonal Antibody
  • Targeted Therapy
  • Therapy
  • AstraZeneca PLC

Human anti-PD-L## monoclonal antibody, Immune checkpoint inhibitor, Oncolytic.

  • Cancer
  • Monoclonal Antibody
  • Oncology
  • Therapy
  • AstraZeneca PLC

PHARMACOKINETICS, PHARMACODYNAMICS AND SAFETY OF A HUMAN ANTI-IL-## monoclonal antibody (sirukumab) in healthy subjects in a first-in-human study.

  • Biosimilar
  • Epidemiology
  • Monoclonal Antibody
  • Forecast
  • AstraZeneca PLC

MediGene AG BioInvent International AB Genmab A/ S Ablynx NV Preclinical Preclinical Preclinical Preclinical Preclinical Preclinical Preclinical mAb mAb mAb mAb mAb mAb mAb Hormonal signaling Undisclosed Undisclosed Undisclosed Undisclosed Undisclosed Undisclosed Monoclonal

  • Immunotherapy
  • Monoclonal Antibody
  • Oncology
  • Therapy
  • AstraZeneca PLC
  • Rising Prevalence and Increasing Disease Awareness to Drive Significant Growth
  • 8.1.3 DEAL VALUE BY STAGE OF DEVELOPMENT, MOLECULE TYPE AND MOLECULAR TARGET

Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma.

  • Asthma
  • Clinical Trial
  • Monoclonal Antibody
  • Therapy
  • AstraZeneca PLC

Monoclonal antibodies account for ## of the ## development projects.

  • Cancer
  • Monoclonal Antibody
  • Targeted Therapy
  • Therapy
  • AstraZeneca PLC
  • CANCER IMMUNOTHERAPIES MARKET, GLOBAL, CO-DEVELOPMENT DEALS VALUED ABOVE $100M, 2006-2016

Safety, Activity, and Immune Correlates of Anti-PD-## Antibody in Cancer.

  • Cancer Immunotherapy
  • Immunotherapy
  • Monoclonal Antibody
  • Therapy
  • AstraZeneca PLC

Gastric cancer

4385 5000 3900
  • Phase III pipeline products in development for gastric cancer
  • Executive Summary

NCI drug dictionary (2016) Anti-MMP-## monoclonal antibody GS-##.

  • Chemotherapy
  • Gastric Cancer
  • Monoclonal Antibody
  • Therapy
  • AstraZeneca PLC
  • MONOCLONAL ANTIBODIES
  • MONOCLONAL ANTIBODIES

Monoclonal antibodies directed at PD-## are designed to prevent PD-## from binding both PD-L## and PD-L##.

  • Monoclonal Antibody
  • Targeted Therapy
  • Therapy
  • Agenus Inc.
  • AstraZeneca PLC

OBINUTUZUMAB: A NEW CLASS OF ANTI-CD## MONOCLONAL ANTIBODY.

  • Epidemiology
  • Hospital
  • Monoclonal Antibody
  • Therapy
  • AstraZeneca PLC
  • CTLA-4 - Antagonists: Yervoy (ipilimumab) combination with other therapeutics - 1/7

Precl Xencor Antibody ## ## PD-## x LAG- ## Antibody PD-## and LAG-## Multiple oncology indications Rec bispecific monoclonal antibody with engineered Fc (Xencor' s XTend technology) LAG-## Antagonists - ##/ ## ## ## LAG-## x PD- L## Bi

  • Cancer Immunotherapy
  • Monoclonal Antibody
  • Therapy
  • AstraZeneca PLC
  • Bristol-Myers Squibb Company

Keytruda is a humanized monoclonal antibody designed to inhibit the PD-## co-inhibitory receptor.

  • Breast Cancer
  • Monoclonal Antibody
  • Targeted Therapy
  • Therapy
  • AstraZeneca PLC
  • OVERVIEW OF ANTI-CD22 IMMUNOTHERAPEUTICS IN DEVELOPMENT
  • 4. Profiles of CD22-Targeted Immunotherapeutics

The immunotoxin Combotox is the ##:## mixture of two murine monoclonal IgG## antibodies, both individually linked to a ricin based toxin.

  • Immunotherapy
  • Medical Biotechnology
  • Monoclonal Antibody
  • AstraZeneca PLC
  • Immunomedics, Inc.
  • MONOCLONAL ANTIBODY TO INHIBIT OX40 LIGAND FOR ASTHMA - DRUG PROFILE
  • MER-2101 - DRUG PROFILE

The drug candidate is a human immunoglobulin monoclonal antibody targeting eotaxin-##.

  • Asthma
  • Monoclonal Antibody
  • United States
  • Company
  • AstraZeneca PLC

Psoriatic arthritis

4385 5000 3900
  • BRODALUMAB DRUG PROFILE
  • PRODUCT PROFILE

Drip Infusion ##, Anti-Human TNF-alpha Monoclonal Antibody.

  • Autoimmune Disease
  • Healthcare
  • Monoclonal Antibody
  • Therapy
  • AstraZeneca PLC
  • PHASE III PIPELINE PRODUCTS IN DEVELOPMENT FOR SYSTEMIC LUPUS ERYTHEMATOSUS

Anifrolumab is a fully human monoclonal antibody against subunit ## of the Type I interferon receptor, IFN-alpha.

  • Genitourinary System Disease
  • Monoclonal Antibody
  • Musculoskeletal Disorder
  • Therapy
  • AstraZeneca PLC
  • MONOCLONAL ANTIBODY TO INHIBIT OX40 LIGAND FOR ASTHMA - DRUG PROFILE
  • MER-2101 - DRUG PROFILE

The drug candidate is a human immunoglobulin monoclonal antibody targeting eotaxin-##.

  • Asthma
  • Monoclonal Antibody
  • Pharmaceutical
  • Therapy
  • AstraZeneca PLC

SUMMARY CHRONIC KIDNEY DISEASE MONOCLONAL ANTIBODIES MONOCLONAL ANTIBODIES Monoclonal antibody therapy uses monoclonal antibodies (mAb) to bind to target cells or proteins that is used in the treatment of various diseases.

  • Monoclonal Antibody
  • Renal Disease
  • Therapy
  • Type 2 Diabetes
  • AstraZeneca PLC