IONIS-PKKRx - Emerging Insight and Market Forecast - 2030

February 2021 •
30 pages •
Report ID: 6025034 •
Format: PDF

Summary
Table of contents

“IONIS-PKKRx - Emerging Insight and Market Forecast - 2030” the report provides comprehensive insights about an investigational product for Hereditary Angioedema in 7 Major Markets. A detailed picture of the IONIS-PKKRx in Seven Major Markets, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan, for the study period 2020–2030 is provided in this report along with a detailed description of the product. The product details cover mechanism of action, dosage and administration, route of synthesis, and Research and development activity including regulatory milestones, and other development activities. Further, it also consists of future market assessments inclusive of the market forecast, SWOT analysis, market competitors, and other emerging therapies.

Overview
IONIS-PKKRx is a second-generation 2’-O-(2-methoxyethyl)-modified chimeric antisense oligonucleotide, designed to bind and selectively reduce prekallikrein (PKK). IONIS-PKK-LRx also known as Donidalorsen is designed to inhibit bradykinin signaling by halting synthesis of prekallikrein (PKK), a precursor of the enzyme kallikrein, which is involved in the formation of bradykinin, a protein that promotes inflammation and dilates blood vessels. IONIS-PKK-LRx was developed using advanced LIgand Conjugated Antisense (LICA) technology platform.

Scope of the report
The report provides insights into:
? A comprehensive product overview including the product description, mechanism of action, dosage and administration, Research and Development activity.
? Elaborated details on regulatory milestones and other development activities have been provided in this report.
? The report also highlights the drug research and development activity details across the United States, Europe and Japan.
? The report also covers the patents information with expiry timeline around IONIS-PKKRx.
? The report contains forecasted sales for IONIS-PKKRx till 2030.
? Comprehensive coverage of the mid-stage emerging therapies (Phase II) for Hereditary Angioedema.
? The report also features the SWOT analysis with analyst insights and key findings of IONIS-PKKRx.

Methodology
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by the team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

IONIS-PKKRx Analytical Perspective
? In-depth IONIS-PKKRx Market Assessment
This report provides a detailed market assessment of IONIS-PKKRx in Seven Major Markets, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan. This segment of the report provides forecasted sales data from 2020 to 2030.

? IONIS-PKKRx Clinical Assessment
The report provides the clinical trials information of IONIS-PKKRx covering trial interventions, trial conditions, trial status, start and completion dates.

Report highlights
? In the coming years, the market scenario for Hereditary Angioedema is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
? The companies and academics are working to assess challenges and seek opportunities that could influence IONIS-PKKRx dominance. The therapies under development are focused on novel approaches to treat/improve the disease condition.
? Other emerging products for Hereditary Angioedema are giving market competition to IONIS-PKKRx and launch of late-stage emerging therapies in the near future will significantly impact the market.
? A detailed description of regulatory milestones, development activities, and some key findings provide the current development scenario of IONIS-PKKRx.
? Our in-depth analysis of the forecasted sales data of IONIS-PKKRx from 2020 to 2030 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the IONIS-PKKRx.

Key Questions
• Which company is developing IONIS-PKKRx along with the phase of the clinical study?
• What is the technology utilized in the development of IONIS-PKKRx?
• What is the product type, route of administration and mechanism of action of IONIS-PKKRx?
• What is the clinical trial status of the study and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the IONIS-PKKRx development?
• What are the key designations that have been granted to IONIS-PKKRx?
• What is the forecasted market scenario of IONIS-PKKRx?
• What is the history of IONIS-PKKRx and what is its future?
• What is the forecasted sales of IONIS-PKKRx in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how these are giving competition to IONIS-PKKRx?
• Which are the late-stage emerging therapies under development for the treatment of the Hereditary Angioedema?

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