Sample Preparation in Genomics, Proteomics, and Epigenomics: Global Markets

Sample Preparation in Genomics, Proteomics, and Epigenomics: Global Markets

  • January 2017
  • 135 pages
  • BCC Research
Report ID: 619256

Use this report to:
- Assess current market dynamics and estimate future demand for sample preparation in genomics, proteomics and epigenomics.
- Gain insight into existing products as well as new developments in genomics, proteomics and epigenomics, issues and factors impacting the global life sciences market.
- Identify major stakeholders, their product portfolio along with the most relevant patents.


Highlights

- The global market for sample preparation in genomics, proteomics and epigenomics reached $5.2 billion in 2015. The market should reach $5.6 billion in 2016 and $7.7 billion by 2021, growing at a compound annual growth rate (CAGR) of 6.5% from 2016 to 2021. - The instruments market for sample preparation in genomics, proteomics and epigenomics reached $1.8 billion in 2015. The market should reach $1.9 billion in 2016 and $2.6 billion by 2021, growing at a CAGR of 6.6% from 2016 to 2021.
- The consumables market for sample preparation in genomics, proteomics and epigenomics reached $1.6 billion in 2015. The market should reach over $1.7 billion in 2016 and $2.4 billion by 2021, growing at a CAGR of 7.1% from 2016 to 2021.



STUDY GOALS AND OBJECTIVES
BCC Research’s goal in preparing this study was to determine the global market and future demand for sample preparation in genomics, proteomics and epigenomics over the five-year period from 2016 to 2021. Our particular interest was in characterizing and quantifying the market for sample preparation in genomics, proteomics and epigenomics by product, end user, geographic region and application.

We also evaluate the market by segmenting it into instruments, consumables, accessories and sample preparation kits. Factors that impact the market for sample preparation have been discussed in detail. Key market dynamics in each regional market worldwide has been discussed in detail. Aspects that affect each subsegment, the drivers, restraints, threats and opportunities have been discussed. Our key objective was to present a comprehensive discussion of where the state-of-the-art is in sample preparation and forecast the future commercial potential for the key market segments.

This discussion will provide a basis for companies to make strategic choices in developing new products and markets, or deciding which segments to focus on to achieve the highest growth. The study will benefit sample preparation companies, pharmaceutical and biotechnology companies, laboratories and service providers, end users, governments around the world, healthcare agencies and others.


REASONS FOR DOING THE STUDY
The completion of the Human Genome Project in 2003 later served to have a major impact on the market for genomics, proteomics and epigenomics. The cost of sequencing has decreased significantly, and there has been rising interest in the fields of genomics and proteomics due to their increasing application in various other fields. Epigenomics is a part of genomics and has recently been applied successfully in cancer treatment. Downstream processing in genomics and proteomics requires a sample that is free of impurities in adequate quantities. Hence, sample preparation for these technologies is as important as downstream processing.

Widespread advancements in scientific research have been made due to the completion of the Human Genome Project. There has been a shift from cellular biology to molecular biology—from studying cell as a structure—to studying the structure and function of the macromolecules found within cells (e.g., proteins and nucleic acids). Genomics, the study of genes and their function, and proteomics, the study of proteins, are fields within the study of molecular biology.

Sample preparation refers to a range of activities that precede most forms of scientific analysis. Sample preparation is generally complex, laborious and one of the most error-prone steps within scientific research. It is nonetheless a universal activity among laboratories whose requirements drive a large and growing market, worldwide. The global market for sample preparation in genomics, proteomics and epigenomics is an interesting market as advances are occurring rapidly. The market is continually evolving to increase the speed and accuracy of sample preparation. Automation and miniaturization are shaping the industry. The market for sample preparation in genomics, proteomics and epigenomics is highly fragmented with many large and small companies such as U.S.-based Agilent Technologies Inc., Bio-Rad Laboratories and Danaher Corp.



SCOPE OF REPORT
This research report categorizes the market for sample preparation in genomics, proteomics and epigenomics by product segment. The major product segments are instruments, consumables, accessories and sample preparation kits. The instruments segment is subdivided into workstations, liquid handling systems, extraction systems and other instruments. Consumables are divided into columns, filters, tubes, plates and other consumables. Sample preparation kits are segmented into purification kits, isolation kits, extraction kits and others.

The global market for sample preparation is segmented by end user into research centers, academic institutes, and government institutes, hospitals and clinics, pharmaceutical and biotechnology companies and others. The markets in North America, Europe, Asia and rest of the world are covered. The market is also segmented by application into genomics, proteomics and epigenomics.



INTENDED AUDIENCE
- Sample preparation instrument manufacturers.
- Sample preparation consumables manufacturers.
- Sample preparation suppliers and distributors.
- Genomics, proteomics and epigenomics research laboratories.
- Genomics, proteomics and epigenomics companies.
- Consulting firms.
- Physicians and hospitals.
- Government agencies.
- Healthcare agencies.




RESEARCH METHODOLOGY
This research study used extensive secondary sources such as directories, databases, white papers, as well as annual reports, SEC filings and other company documents. Secondary research was mainly used to identify and collect information for the extensive technical, market-oriented and commercial study of this global market. It was also used to obtain key information about major market participants, market classification and segmentation according to industry trends, geographic markets and important developments. During the course of this study, a database of key industry leaders was created using secondary research, and was then used for primary research.

Primary sources include industry experts such as CEOs, vice presidents, marketing directors and other executives from companies and organizations involved in sample preparation in genomics and proteomics. All primary sources were interviewed to obtain and verify critical qualitative and quantitative information and to assess future prospects. Primary research was also done to understand segment types, industry trends and key players as well as the competitive landscape for each product. Key market dynamics such as drivers, restraints, opportunities, important issues, key player strategies and recent trends were explored.

Primary research was used to gather extensive information and to verify and validate the critical numbers derived after calculating market statistics, including market size estimations, market forecasting, market breakdown and data triangulation. Qualitative and quantitative analyses were based on secondary and primary sources. Key information obtained has been discussed throughout the report.



ANALYST'S CREDENTIALS
Neha Maliwal, a graduate in biotechnology and a postgraduate in marketing and biotechnology at the University of Pune (India), is the author of this study and numerous others, including the analyses of related markets such as antibiotics, radiopharmaceuticals, radiotherapy, healthcare business process outsourcing (BPO) and biotechnology instrumentation.
CHAPTER 1
INTRODUCTION 2
STUDY GOALS AND OBJECTIVES 2
REASONS FOR DOING THE STUDY 2
SCOPE OF REPORT 3
INTENDED AUDIENCE 3
RESEARCH METHODOLOGY 3
ANALYST'S CREDENTIALS 4
RELATED BCC RESEARCH REPORTS 4
BCC RESEARCH WEBSITE 4
DISCLAIMER 5
CHAPTER 2 SUMMARY 7
SUMMARY TABLE GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 7
SUMMARY FIGURE GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, 2015-2021 ($ MILLIONS) 8
CHAPTER 3 MARKET OVERVIEW 10
INTRODUCTION 10
HISTORICAL PERSPECTIVE 11
TABLE 1 TIMELINE OF IMPORTANT DISCOVERIES IN THE FIELD OF GENOMICS 12
DEFINITIONS 12
GENOMICS 12
TABLE 2 GENOME SIZES OF MODEL SYSTEMS 13
Comparative Genomics 13
Functional Genomics 14
Structural Genomics 14
PROTEOMICS 14
Expression Proteomics 15
Structural Proteomics 16
Functional Proteomics 16
EPIGENOMICS 16
TABLE 3 DIFFERENCES BETWEEN GENOMICS AND PROTEOMICS 17
SAMPLE PREPARATION 18
MOLECULAR BIOLOGY 18
DNA STRUCTURE 18
TABLE 4 NITROGEN BASE IN DNA 19
DNA REPLICATION 19
TABLE 5 ENZYMES USED IN DNA REPLICATION 19
PROTEINS 19
TABLE 6 AMINO ACIDS 20
CENTRAL PRINCIPLES 20
TRENDS IN R&D 21
GLOBAL SPENDING ON R&D 21
DEVELOPING COUNTRIES TO INCREASE R&D SPENDING 21
CHINA - A RISING HUB FOR SCIENCE AND TECHNOLOGY 21
Growing R&D Expenditure 21
Increase in Number of Knowledge- and Technology-Intensive (KTI) Industries 22
Improved Research Output 22
R&D FUNDING 22
GLOBAL INCREASE IN THE NUMBER OF RESEARCHERS 22
MARKET DYNAMICS 23
FIGURE 1 MARKET DYNAMICS OF GENOMICS, PROTEOMICS AND EPIGENOMICS 23
DRIVERS 23
Innovation and Automation 23
Demand for High Quality Samples 24
Automation Leading to Better Result 24
Personal Genomics Market-Booming Niche 25
High Return of Investment from Genomics and Proteomics 25
High Interest of Venture Capitalists in Genomics and Proteomics 25
RESTRAINTS 26
Cost of Equipment 26
High Cost of Complex Sample Preparation 26
FIGURE 2 COMPARISON OF COST DISTRIBUTION OF NEXT-GENERATION SEQUENCING-PAST, PRESENT AND FUTURE (%) 26
OPPORTUNITIES 27
Wide Application of Genomics 27
Increasing Demand for Proteomics 28
CHALLENGES 28
Data Privacy a Major Concern 28
Apprehension Around Genetic Testing May Slow the Market 28
LIMITATIONS OF SAMPLE PREPARATION 29
CHAPTER 4 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT 31
INSTRUMENTS 31
GLOBAL MARKET FOR INSTRUMENTS BY TYPE 31
TABLE 7 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY INSTRUMENT TYPE, THROUGH 2021 ($ MILLIONS) 31
REGIONAL MARKETS FOR INSTRUMENTS 32
TABLE 8 FOR SAMPLE PREPARATION INSTRUMENTS USED IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 32
INSTRUMENT MARKET SUBSEGMENTS 32
Workstations 32
Regional Markets for Workstations 33
TABLE 9 GLOBAL MARKET FOR WORKSTATIONS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 33
Liquid Handling Systems 33
Regional Markets for Liquid Handling Systems 34
TABLE 10 GLOBAL MARKET FOR LIQUID HANDLING SYSTEMS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 34
Market for Liquid Handling Systems by Product Segment 35
TABLE 11 GLOBAL MARKET FOR LIQUID HANDLING SYSTEMS USED IN SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY TYPE OF SYSTEM, THROUGH 2021 ($ MILLIONS) 35
Liquid Handling Workstations 35
Regional Markets for Liquid Handling Workstations 36
TABLE 12 GLOBAL MARKET FOR LIQUID HANDLING WORKSTATIONS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 36
Pipetting Systems 37
Regional Markets for Pipetting Systems 37
TABLE 13 GLOBAL MARKET FOR PIPETTING SYSTEMS SAMPLE PREPARATION OF GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 38
Microplate Dispensers 38
Regional Markets for Microplate Dispensers 38
TABLE 14 GLOBAL MARKET FOR MICROPLATE DISPENSERS FOR SAMPLE PREPARATION OF GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 39
Microplate Washers 39
Regional Markets for Microplate Washers 40
TABLE 15 GLOBAL MARKET FOR MICROPLATE WASHERS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 40
"Other" Liquid Handling Systems 40
Regional Markets for "Other" Liquid Handling Systems 40
TABLE 16 GLOBAL MARKET FOR OTHER TYPES OF LIQUID HANDLING SYSTEMS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 41
Extraction Systems 41
Regional Markets for Extraction Systems 42
TABLE 17 GLOBAL MARKET FOR EXTRACTION SYSTEMS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 42
"Other" Sample Preparation Instruments 43
Regional Markets for "Other" Sample Preparation Instruments 43
TABLE 18 GLOBAL MARKET FOR OTHER SAMPLE PREPARATION INSTRUMENTS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 44
CONSUMABLES 44
REGIONAL MARKETS FOR CONSUMABLES 44
TABLE 19 GLOBAL MARKET FOR CONSUMABLES USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 45
MARKET FOR CONSUMABLES BY PRODUCT TYPE 45
TABLE 20 GLOBAL MARKET FOR CONSUMABLES FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY TYPE, THROUGH 2021 ($ MILLIONS) 45
Columns 45
Regional Markets for Columns 47
TABLE 21 GLOBAL MARKET FOR COLUMNS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 47
Filters 47
Regional Markets for Filters 48
TABLE 22 GLOBAL MARKET FOR FILTERS FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 48 Tubes 48
Regional Markets for Tubes 49
TABLE 23 GLOBAL MARKET FOR TUBES FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 49 Microplates 49
Regional Markets for Plates 50
TABLE 24 GLOBAL MARKET FOR PLATES FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 50 Others 50
Regional Markets for "Other" Types of Consumables 51
TABLE 25 GLOBAL MARKET FOR OTHER TYPES OF CONSUMABLES USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 51
ACCESSORIES 51
REGIONAL MARKETS FOR ACCESSORIES 51
TABLE 26 GLOBAL MARKET FOR ACCESSORIES FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 52
SAMPLE PREPARATION KITS 52
TABLE 27 SAMPLE PREPARATION KITS BY COMPANY AND SAMPLE SOURCE 53
TABLE 28 OTHER SAMPLE PREPARATION KITS BY COMPANY 54
TABLE 29 NUMBER OF PUBLICATIONS CITING EACH TYPE OF MAIN DNA EXTRACTION AND PURIFICATION KITS OFFERED BY EACH OF THE MAJOR SUPPLIERS, AS OF APRIL 1, 2015 55
REGIONAL MARKETS FOR SAMPLE PREPARATION KITS 56
TABLE 30 GLOBAL MARKET FOR SAMPLE PREPARATION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 56
MARKET FOR SAMPLE PREPARATION KITS BY PRODUCT SEGMENT 57
TABLE 31 GLOBAL MARKET FOR SAMPLE PREPARATION KITS BY TYPE, THROUGH 2021 ($ MILLIONS) 57
Purification Kits 57
TABLE 32 OVERVIEW OF DNA PURIFICATION KITS FOR PCR PRODUCTS AND ENZYMATIC REACTIONS 57
Regional Markets for Purification Kits 58
TABLE 33 GLOBAL MARKET FOR PURIFICATION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 59
Market for Purification Kits by Product Segment 59
TABLE 34 GLOBAL MARKET FOR PURIFICATION KITS BY TYPE, THROUGH 2021 ($ MILLIONS) 59
Isolation Kits 59
DNA Extraction of Bacterial Cells 60
TABLE 35 OVERVIEW OF DNA EXTRACTION AND PURIFICATION KITS FOR MICROBES 60
Kits Specifically for Whole Blood 62
Regional Markets for Isolation Kits 62
TABLE 36 GLOBAL MARKET FOR ISOLATION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 62
Market for Isolation Kits by Product Segment 63
TABLE 37 GLOBAL MARKET FOR ISOLATION KITS BY TYPE, THROUGH 2021 ($ MILLIONS) 63
Extraction Kits 63
DNA Extraction from Animal Cells and Tissues 63
TABLE 38 OVERVIEW OF EXTRACTION AND PURIFICATION DNA KITS FOR ANIMAL TISSUE AND CELLS 64
DNA Extraction from Plant Tissue and Cells 66
TABLE 39 OVERVIEW OF DNA EXTRACTION AND PURIFICATION KITS FOR PLANT TISSUE AND CELLS 67
Kits for Animal Tissue and Cells and Microbes 68
TABLE 40 OVERVIEW OF DNA EXTRACTION AND PURIFICATION KITS FOR ANIMAL TISSUE AND CELLS AND MICROBES 68
Kits for Mammalian, Microbial and Plant Cells 70
TABLE 41 OVERVIEW OF DNA EXTRACTION AND PURIFICATION KITS FOR SAMPLES FROM ANIMAL, MICROBIAL AND PLANT ORIGIN 70
Kits for DNA Extraction from Gels 72
Regional Markets for Extraction Kits 72
TABLE 42 GLOBAL MARKET FOR EXTRACTION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 72
Market for Extraction Kits by Product Segment 73
TABLE 43 GLOBAL MARKET FOR EXTRACTION KITS BY TYPE, THROUGH 2021 ($ MILLIONS) 73
Others Kits 73
Regional Markets for "Other" Types of Preparation Kits 74
TABLE 44 GLOBAL MARKET FOR OTHER SAMPLE PREPARATION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 74
CHAPTER 5 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY APPLICATION SEGMENT 76
TABLE 45 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY APPLICATION SEGMENT, THROUGH 2021 ($ MILLIONS) 76
GENOMICS APPLICATIONS 76
MEDICINE 76
Pharmacogenomics 76
TABLE 46 THE FOUR DRUG METABOLISM PHENOTYPES (%) 77
Cancer 77
Diagnosing and Characterizing Genetic Disorders 77
Personalized Genetics 78
AGRICULTURE 78
PROTEOMICS APPLICATIONS 78
ONCOLOGY 78
BIOMEDICAL 79
AGRICULTURE 79
FOOD MICROBIOLOGY 79
EPIGENOMICS APPLICATIONS 79
CHAPTER 6 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY END USER TYPE 82
TABLE 47 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY END USER TYPE, THROUGH 2021 ($ MILLIONS) 82
RESEARCH CENTERS, ACADEMIC INSTITUTES AND GOVERNMENT AGENCIES 82
HOSPITALS AND CLINICS 83
PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES 83
OTHERS 83
CHAPTER 7 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY GEOGRAPHIC REGION 85
TABLE 48 GLOBAL MARKET FOR SAMPLE PREPARATION OF GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 85
NORTH AMERICA 86
NATIONAL INSTITUTES OF HEALTH 86
DECREASING R&D SPENDING 88
GROWING GENETIC TESTING MARKET 88
TABLE 49 DIRECT-TO-CONSUMER GENETIC TESTS 89
GENETICALLY MODIFIED CROPS 89
TABLE 50 SUMMARY OF THE FDA'S INVENTORY OF COMPLETED BIOTECHNOLOGY CONSULTATIONS ON GENETICALLY ENGINEERED FOODS, JUNE 30, 2015 90
GOVERNMENT AND PRIVATE INITIATIVES 91
DRUG DISCOVERY DRIVING THE MARKET FOR PROTEOMICS 92
EPIGENOMICS 92
TABLE 51 NORTH AMERICAN MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 92
EUROPE 93
TABLE 52 GROSS DOMESTIC EXPENDITURES ON R &D BY COUNTRY, 2011-2013 (%) 93
PUBLIC HEALTH GENOMICS EUROPEAN NETWORK (PHGEN) 94
U.K. 100,000 GENOMES PROJECT 95
$3.4 MILLION INVESTMENT INTO THREE-DIMENSIONAL GENOMICS 95
NEW INTERNATIONAL GENOME RESEARCH CENTRE IN DENMARK 96
IMPACT OF BREXIT 96
TABLE 53 EUROPEAN MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 97
ASIA 97
CHINA LEADING ASIA AND POSITIONED TO LEAD WORLD GENOMICS 97
GENOMEASIA 100K INITIATIVE 98
ASIA A NEW HUB FOR R&D 98
GLOBAL COLLABORATION REQUIRED 99
TABLE 54 EAST ASIAN CENTERS AND RESOURCES FOR HUMAN GENOMIC RESEARCH 99
TABLE 55 ELSI PRACTICES AND REGULATION OF HUMAN GENOMIC RESEARCH IN EAST ASIA 101
TABLE 56 ASIAN MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 102
REST OF THE WORLD 103
AUSTRALIA 103
LATIN AMERICAN COUNTRIES 103
TABLE 57 GENETIC DISORDERS UNDER BRAZILIAN FEDERAL CLINICAL PROTOCOLS AND GUIDELINES FOR TREATMENT INCLUDING NEWBORN SCREENING 104
TABLE 58 REST OF THE WORLD MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 105
CHAPTER 8 COMPANY PROFILES 107
AGILENT TECHNOLOGIES INC. 107
FINANCIALS 107
TABLE 59 AGILENT TECHNOLOGIES REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 107
DEVELOPMENTS 108
TABLE 60 AGILENT TECHNOLOGIES DEVELOPMENTS 108
BIO-RAD LABORATORIES INC. 108
FINANCIALS 109
TABLE 61 BIO-RAD LABORATORIES REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 109
DEVELOPMENTS 109
TABLE 62 BIO-RAD LABORATORIES DEVELOPMENTS 109
DANAHER CORP. 110
FINANCIALS 111
TABLE 63 DANAHER REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 111
TABLE 64 DANAHER'S REVENUE DISTRIBUTION BY SEGMENT, 2013-2015 (%) 111
DEVELOPMENTS 112
TABLE 65 DANAHER DEVELOPMENTS 112
HAMILTON CO. 113
DEVELOPMENT 114
TABLE 66 HAMILTON CO. DEVELOPMENTS 114
ILLUMINA INC. 114
FINANCIALS 114
TABLE 67 ILLUMINA REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 114
DEVELOPMENTS 115
TABLE 68 ILLUMINA DEVELOPMENTS 115
MERCK MILLIPORE 116
FINANCIALS 116
TABLE 69 MERCK LIFE SCIENCE REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS) 116
DEVELOPMENTS 117
TABLE 70 MERCK LIFE SCIENCE DEVELOPMENTS 117
NORGENBIOTEK CORP. 117
DEVELOPMENTS 118
TABLE 71 NORGENBIOTEK DEVELOPMENTS 118
NUGEN TECHNOLOGIES INC. 118
DEVELOPMENTS 119
TABLE 72 NUGEN TECHNOLOGIES DEVELOPMENTS 119
PERKINELMER INC. 119
FINANCIALS 120
TABLE 73 PERKINELMER REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 120
DEVELOPMENTS 120
TABLE 74 PERKINELMER DEVELOPMENTS 120
PRESSURE BIOSCIENCES INC. 121
FINANCIALS 121
TABLE 75 PRESSURE BIOSCIENCES INC REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 122
DEVELOPMENTS 122
TABLE 76 PRESSURE BIOSCIENCES DEVELOPMENTS 122
QIAGEN GMBH 123
FINANCIALS 123
TABLE 77 QIAGEN REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 123
DEVELOPMENTS 124
TABLE 78 QIAGEN DEVELOPMENTS 124
ROCHE 125
FINANCIALS 125
TABLE 79 ROCHE REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 125
DEVELOPMENTS 125
TABLE 80 ROCHE DEVELOPMENTS 126
SIGMA-ALDRICH CORP. 126
DEVELOPMENTS 127
TABLE 81 SIGMA-ALDRICH DEVELOPMENTS 127
TECAN GROUP LTD. 127
FINANCIALS 127
TABLE 82 TECAN GROUP REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 128
DEVELOPMENTS 128
TABLE 83 TECAN GROUP DEVELOPMENTS 128
THERMO FISHER SCIENTIFIC INC. 129
FINANCIALS 129
TABLE 84 THERMO FISHER REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 129
DEVELOPMENTS 130
TABLE 85 THERMO FISHER DEVELOPMENTS 130
WATERS CORP. 130
FINANCIALS 131
TABLE 86 WATER CORP. REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 131
PRODUCTS 131
DEVELOPMENTS 132
TABLE 87 WATER CORP. DEVELOPMENTS 132
CHAPTER 9 COMPETITIVE LANDSCAPE 134
TABLE 88 MAJOR MERGERS, ACQUISITIONS, COLLABORATIONS, PARTNERSHIP, SPIN-OFFS AND AGREEMENTS 134
TABLE 89 FDA CLEARANCES AND APPROVALS 138
TABLE 90 NEW PRODUCT LAUNCHES 139
CHAPTER 10 LIST OF ACRONYMS 145


LIST OF TABLES
SUMMARY TABLE GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 7
TABLE 1 TIMELINE OF IMPORTANT DISCOVERIES IN THE FIELD OF GENOMICS 12
TABLE 2 GENOME SIZES OF MODEL SYSTEMS 13
TABLE 3 DIFFERENCES BETWEEN GENOMICS AND PROTEOMICS 17
TABLE 4 NITROGEN BASE IN DNA 19
TABLE 5 ENZYMES USED IN DNA REPLICATION 19
TABLE 6 AMINO ACIDS 20
TABLE 7 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY INSTRUMENT TYPE, THROUGH 2021 ($ MILLIONS) 31
TABLE 8 FOR SAMPLE PREPARATION INSTRUMENTS USED IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 32
TABLE 9 GLOBAL MARKET FOR WORKSTATIONS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 33
TABLE 10 GLOBAL MARKET FOR LIQUID HANDLING SYSTEMS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 34
TABLE 11 GLOBAL MARKET FOR LIQUID HANDLING SYSTEMS USED IN SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY TYPE OF SYSTEM, THROUGH 2021 ($ MILLIONS) 35
TABLE 12 GLOBAL MARKET FOR LIQUID HANDLING WORKSTATIONS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 36
TABLE 13 GLOBAL MARKET FOR PIPETTING SYSTEMS SAMPLE PREPARATION OF GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 38
TABLE 14 GLOBAL MARKET FOR MICROPLATE DISPENSERS FOR SAMPLE PREPARATION OF GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 39
TABLE 15 GLOBAL MARKET FOR MICROPLATE WASHERS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 40
TABLE 16 GLOBAL MARKET FOR OTHER TYPES OF LIQUID HANDLING SYSTEMS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 41
TABLE 17 GLOBAL MARKET FOR EXTRACTION SYSTEMS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 42
TABLE 18 GLOBAL MARKET FOR OTHER SAMPLE PREPARATION INSTRUMENTS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 44
TABLE 19 GLOBAL MARKET FOR CONSUMABLES USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 45
TABLE 20 GLOBAL MARKET FOR CONSUMABLES FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY TYPE, THROUGH 2021 ($ MILLIONS) 45
TABLE 21 GLOBAL MARKET FOR COLUMNS USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 47
TABLE 22 GLOBAL MARKET FOR FILTERS FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 48
TABLE 23 GLOBAL MARKET FOR TUBES FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 49
TABLE 24 GLOBAL MARKET FOR PLATES FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 50
TABLE 25 GLOBAL MARKET FOR OTHER TYPES OF CONSUMABLES USED FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 51
TABLE 26 GLOBAL MARKET FOR ACCESSORIES FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 52
TABLE 27 SAMPLE PREPARATION KITS BY COMPANY AND SAMPLE SOURCE 53
TABLE 28 OTHER SAMPLE PREPARATION KITS BY COMPANY 54
TABLE 29 NUMBER OF PUBLICATIONS CITING EACH TYPE OF MAIN DNA EXTRACTION AND PURIFICATION KITS OFFERED BY EACH OF THE MAJOR SUPPLIERS, AS OF APRIL 1, 2015 55
TABLE 30 GLOBAL MARKET FOR SAMPLE PREPARATION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 56
TABLE 31 GLOBAL MARKET FOR SAMPLE PREPARATION KITS BY TYPE, THROUGH 2021 ($ MILLIONS) 57
TABLE 32 OVERVIEW OF DNA PURIFICATION KITS FOR PCR PRODUCTS AND ENZYMATIC REACTIONS 57
TABLE 33 GLOBAL MARKET FOR PURIFICATION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 59
TABLE 34 GLOBAL MARKET FOR PURIFICATION KITS BY TYPE, THROUGH 2021 ($ MILLIONS) 59
TABLE 35 OVERVIEW OF DNA EXTRACTION AND PURIFICATION KITS FOR MICROBES 60
TABLE 36 GLOBAL MARKET FOR ISOLATION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 62
TABLE 37 GLOBAL MARKET FOR ISOLATION KITS BY TYPE, THROUGH 2021 ($ MILLIONS) 63
TABLE 38 OVERVIEW OF EXTRACTION AND PURIFICATION DNA KITS FOR ANIMAL TISSUE AND CELLS 64
TABLE 39 OVERVIEW OF DNA EXTRACTION AND PURIFICATION KITS FOR PLANT TISSUE AND CELLS 67
TABLE 40 OVERVIEW OF DNA EXTRACTION AND PURIFICATION KITS FOR ANIMAL TISSUE AND CELLS AND MICROBES 68
TABLE 41 OVERVIEW OF DNA EXTRACTION AND PURIFICATION KITS FOR SAMPLES FROM ANIMAL, MICROBIAL AND PLANT ORIGIN 70
TABLE 42 GLOBAL MARKET FOR EXTRACTION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 72
TABLE 43 GLOBAL MARKET FOR EXTRACTION KITS BY TYPE, THROUGH 2021 ($ MILLIONS) 73
TABLE 44 GLOBAL MARKET FOR OTHER SAMPLE PREPARATION KITS BY REGION, THROUGH 2021 ($ MILLIONS) 74
TABLE 45 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY APPLICATION SEGMENT, THROUGH 2021 ($ MILLIONS) 76
TABLE 46 THE FOUR DRUG METABOLISM PHENOTYPES (%) 77
TABLE 47 GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY END USER TYPE, THROUGH 2021 ($ MILLIONS) 82
TABLE 48 GLOBAL MARKET FOR SAMPLE PREPARATION OF GENOMICS, PROTEOMICS AND EPIGENOMICS BY REGION, THROUGH 2021 ($ MILLIONS) 85
TABLE 49 DIRECT-TO-CONSUMER GENETIC TESTS 89
TABLE 50 SUMMARY OF THE FDA'S INVENTORY OF COMPLETED BIOTECHNOLOGY CONSULTATIONS ON GENETICALLY ENGINEERED FOODS, JUNE 30, 2015 90
TABLE 51 NORTH AMERICAN MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 92
TABLE 52 GROSS DOMESTIC EXPENDITURES ON R &D BY COUNTRY, 2011-2013 (%) 93
TABLE 53 EUROPEAN MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 97
TABLE 54 EAST ASIAN CENTERS AND RESOURCES FOR HUMAN GENOMIC RESEARCH 99
TABLE 55 ELSI PRACTICES AND REGULATION OF HUMAN GENOMIC RESEARCH IN EAST ASIA 101
TABLE 56 ASIAN MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 102
TABLE 57 GENETIC DISORDERS UNDER BRAZILIAN FEDERAL CLINICAL PROTOCOLS AND GUIDELINES FOR TREATMENT INCLUDING NEWBORN SCREENING 104
TABLE 58 REST OF THE WORLD MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, THROUGH 2021 ($ MILLIONS) 105
TABLE 59 AGILENT TECHNOLOGIES REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 107
TABLE 60 AGILENT TECHNOLOGIES DEVELOPMENTS 108
TABLE 61 BIO-RAD LABORATORIES REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 109
TABLE 62 BIO-RAD LABORATORIES DEVELOPMENTS 109
TABLE 63 DANAHER REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 111
TABLE 64 DANAHER'S REVENUE DISTRIBUTION BY SEGMENT, 2013-2015 (%) 111
TABLE 65 DANAHER DEVELOPMENTS 112
TABLE 66 HAMILTON CO. DEVELOPMENTS 114
TABLE 67 ILLUMINA REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 114
TABLE 68 ILLUMINA DEVELOPMENTS 115
TABLE 69 MERCK LIFE SCIENCE REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS) 116
TABLE 70 MERCK LIFE SCIENCE DEVELOPMENTS 117
TABLE 71 NORGENBIOTEK DEVELOPMENTS 118
TABLE 72 NUGEN TECHNOLOGIES DEVELOPMENTS 119
TABLE 73 PERKINELMER REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 120
TABLE 74 PERKINELMER DEVELOPMENTS 120
TABLE 75 PRESSURE BIOSCIENCES INC REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 122
TABLE 76 PRESSURE BIOSCIENCES DEVELOPMENTS 122
TABLE 77 QIAGEN REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 123
TABLE 78 QIAGEN DEVELOPMENTS 124
TABLE 79 ROCHE REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 125
TABLE 80 ROCHE DEVELOPMENTS 126
TABLE 81 SIGMA-ALDRICH DEVELOPMENTS 127
TABLE 82 TECAN GROUP REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 128
TABLE 83 TECAN GROUP DEVELOPMENTS 128
TABLE 84 THERMO FISHER REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 129
TABLE 85 THERMO FISHER DEVELOPMENTS 130
TABLE 86 WATER CORP. REVENUES AND R &D EXPENDITURES, 2013-2015 ($ MILLIONS/%) 131
TABLE 87 WATER CORP. DEVELOPMENTS 132
TABLE 88 MAJOR MERGERS, ACQUISITIONS, COLLABORATIONS, PARTNERSHIP, SPIN-OFFS AND AGREEMENTS 134
TABLE 89 FDA CLEARANCES AND APPROVALS 138
TABLE 90 NEW PRODUCT LAUNCHES 139


LIST OF FIGURES
SUMMARY FIGURE GLOBAL MARKET FOR SAMPLE PREPARATION IN GENOMICS, PROTEOMICS AND EPIGENOMICS BY PRODUCT SEGMENT, 2015-2021 ($ MILLIONS) 8
FIGURE 1 MARKET DYNAMICS OF GENOMICS, PROTEOMICS AND EPIGENOMICS 23
FIGURE 2 COMPARISON OF COST DISTRIBUTION OF NEXT-GENERATION SEQUENCING-PAST, PRESENT AND FUTURE (%) 26
Country=World Industry=Genomics ParentIndustry=Biotechnology Date=201701 Topic=MarketReport Publisher=BCCResearch Price=6000