30 reports

  • 4. KEY INFERENCES

RENAL DISEASES ##. ##. ## RAPID TECHNOLOGICAL ADVANCES IN THE FIELD OF GENETICS Advances in the field of genetic technology during the last decade have enlightened our knowledge regarding genetic regulatory pathways related to renal biomarkers.

  • Renal Disease
  • United States
  • World
  • Market Size
  • Thermo Fisher Scientific, Inc.

Immunohematology, ##(##), ##-## < PMID> ##< / PMID>.

  • Renal Disease
  • Japan
  • United States
  • Amgen Inc.
  • Roche Group

RHEUMATOLOGY; ##(##): ##-##.

  • Renal Disease
  • France
  • Italy
  • United States
  • Forecast

Monosodium Luminol effectively reverse oxidative stress induced by xenobiotic and genetic triggers, and by serving as a buffer to restore and maintain intracellular reduction and oxidationredox homeostasis.

  • Chronic Disease
  • Renal Disease
  • United States
  • Product Initiative
  • RPI
  • CLINICAL TRIALS BY G7 COUNTRIES: PROPORTION OF POLYCYSTIC KIDNEY DISEASE TO GENETIC DISORDERS CLINICAL TRIALS
  • CLINICAL TRIALS BY E7 COUNTRIES: PROPORTION OF POLYCYSTIC KIDNEY DISEASE TO GENETIC DISORDERS CLINICAL TRIALS

Polycystic Kidney Disease Global Clinical Trials Review, H1, 2018 Summary GlobalData’s clinical trial report, “Polycystic Kidney Disease Global Clinical Trials Review, H1, 2018" provides an overview of Polycystic Kidney Disease clinical trials scenario.This report provides top line data relating...

  • Pharmaceutical
  • Renal Disease
  • World
  • Product Initiative
  • Otsuka Pharmaceutical Co., Ltd.
  • Proportion of Polycystic Kidney Disease to Genetic Disorders Clinical Trials, G7 Countries (%), 2016*
  • Clinical Trials by E7 Countries: Proportion of Polycystic Kidney Disease to Genetic Disorders Clinical Trials

Polycystic Kidney Disease Global Clinical Trials Review, H2, 2016 Summary GlobalData's clinical trial report, “Polycystic Kidney Disease Global Clinical Trials Review, H2, 2016" provides an overview of Polycystic Kidney Disease clinical trials scenario. This report provides top line data relating to the clinical trials...

  • Drug Discovery And Development
  • Genetic Disorder
  • Renal Disease
  • World
  • Product Initiative
  • UPDATES

“Chronic Kidney Disease (CKD) Pipeline Analysis” gives comprehensive insight on the various drugs being developed for the treatment of CKD. The report covers all the drugs being developed in various phases (Discovery, Preclinical, Clinical & Marketing). The pipeline focuses on novel pharmacologic drugs & regenerative medicines covering small...

  • Renal Disease
  • Angion Biomedica Corp.
  • Astellas Pharma Inc.
  • AstraZeneca PLC
  • Eli Lilly & Co.

The molecules developed by Companies in Filing rejected/ Withdrawn, Phase I, IND/ CTA Filed and Preclinical stages are ##, ##, ## and ## respectively.

  • Renal Disease
  • United States
  • World
  • Product Initiative
  • CTI BioPharma Corp.
  • Renal Diseases, Global, Pipeline Programs Targeting Connective Tissue Growth Factor, 2017
  • Renal Diseases, Global, AKI Types, 2017

In Vivo; ##(##): ##-## Okamura DM, et al. (2011).

  • Chronic Disease
  • Renal Disease
  • World
  • Deals & Alliance
  • Galectin Therapeutics Inc.
  • Polycystic Kidney Disease - Companies Involved in Therapeutics Development
  • Drug candidate is under development for the treatment of polycystic kidney disease.

The company primarily focuses on rare genetic disorders, kidney diseases, orthopedics, organ transplant, cancer, and immune disease.

  • Renal Disease
  • Therapy
  • United States
  • Company
  • Product Initiative

Similarly, the universities portfolio in Preclinical and Discovery stages comprises ## and ## molecules, respectively.

  • Renal Disease
  • United States
  • World
  • Product Initiative
  • ChemoCentryx, Inc.

Patients will be randomized (##:##:##) to receive ## mg pacritinib twice daily (BID), ## mg pacritinib once daily (QD) or best available therapy.

  • Renal Disease
  • Therapy
  • United States
  • World
  • CTI BioPharma Corp.
  • MAR 21, 2017: WORLD LEADING PREDICTIVE DIAGNOSTIC TEST FOR DIABETIC KIDNEY DISEASE CRISIS TO ROLL-OUT IN ASIA WITH CHINA AND SINGAPORE PATENTS AND COMMERCIALISATION PARTNERS

It is a powerful alternative to genetic testing.

  • Diabetes
  • Laboratory
  • Proteomics
  • Renal Disease
  • GlobalData's company

The company' s target therapeutic areas include rheumatoid arthritis, HIV/ AIDS, respiratory infections, cancer, diabetes, men' s and women' s health, and genetic conditions.

  • In Vitro Diagnostics
  • Renal Disease
  • North America
  • United States
  • Sysmex Corporation
  • May 31, 2018: Goldfinch Bio Presents Data on TRPC5 Inhibition as a Target for Proteinuric Kidney Disease and Announces GFB-887 as Lead Drug Program to Treat FSGS

The company develops biologic therapeutic products for the treatment of severe disease states, including genetic diseases, hematologic diseases, cancer, neurological and autoimmune disorders.

  • Renal Disease
  • Type 2 Diabetes
  • United States
  • Product Initiative
  • ChemoCentryx, Inc.

The molecules developed by companies in Pre-Registration, Phase I, Preclinical and Discovery stages are ##, ##, ## and ## respectively.

  • Renal Disease
  • Therapy
  • United States
  • Product Initiative
  • ChemoCentryx, Inc.

The molecules developed by companies in Phase III, Phase I and Preclinical stages are ##, ## and ## respectively.

  • Renal Disease
  • Therapy
  • United States
  • Product Initiative
  • ChemoCentryx, Inc.

Boehringer Sohn AG & Co KG ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## ## Biogen Inc Source: GlobalData' s Pharma Intelligence Center Clinical Trials Database (*)Trials are taken for a time period of 1995 - 2018 2018 trials are taken as

  • Hormones
  • Renal Disease
  • Therapy
  • World
  • Merck & Co., Inc.

It provides research origins on cancer and inflammation therapies by utilizing the genetic information and analysis technology.

  • Chronic Disease
  • Renal Disease
  • United States
  • Company
  • Product Initiative
  • Other Developmental Activities
  • POLYCYSTIC KIDNEY DISEASE - DORMANT PROJECTS, H2 2017

ADPKD is a devastating, life-threatening and currently incurable genetic disorder in which kidney cysts progressively form throughout life.

  • Renal Disease
  • Therapy
  • United States
  • Company Operations
  • Product Initiative

In the study, mice with severe hypophosphatasia, due to a genetic defect (knock-out) in one of the genes encoding for alkaline phosphatase were administered daily subcutaneous injections of recAP at doses of ##, ## or ##mg/ kg, from birth up to ## days.

  • Hospital
  • Renal Disease
  • United States
  • Product Initiative
  • Quark

This study evaluated the efficacy and safety of roxadustat compared to darbepoetin alfa (genetical recombination) (" darbepoetin alfa" ) in hemodialysis-dependent chronic kidney disease (CKD) patients with anemia and previously treated with recombinant human erythropoietin (rHuEPO)

  • Blood Disease
  • Renal Disease
  • World
  • Product Initiative
  • F. Hoffmann-La Roche Ltd.

Mariel intends to advance clinical trial in osteoarthritis (OA) and for chronic kidney disease (CKD) and Alport' s disease, a genetic kidney fibrosis disease.

  • Diabetes
  • Renal Disease
  • United States
  • Company
  • Product Initiative

THE THERAPEUTIC CANDIDATE CONSTITUTES OF DONOR-DERIVED ALLOGENEIC MESENCHYMAL STEM CELLS (MSCS) GENETICALLY ENGINEERED WITH A THERAPEUTIC TRANSGENE.

  • Diabetes
  • Renal Disease
  • United States
  • Company
  • Product Initiative

The disease in children is generally from genetic origin while adults mostly develop dRTA as a result of autoimmune disease.

  • Clinical Trial
  • Drug Discovery And Development
  • Hormone
  • Renal Disease
  • World

IN THE STUDY, MICE WITH SEVERE HYPOPHOSPHATASIA, DUE TO A GENETIC DEFECT (KNOCK-OUT) IN ONE OF THE GENES ENCODING FOR ALKALINE PHOSPHATASE WERE ADMINISTERED DAILY SUBCUTANEOUS INJECTIONS OF RECAP AT DOSES OF ##, ## OR ##MG/ KG, FROM BIRTH UP TO ## DAYS.

  • Genitourinary System Disease
  • Renal Disease
  • United States
  • Product Initiative
  • Quark

The prominent features of this report are - ##.

  • Clinical Trial
  • Hormones
  • Pharmaceutical
  • Renal Disease
  • World

It provides research origins on cancer and inflammation therapies by utilizing the genetic information and analysis technology.

  • Diabetes
  • Genitourinary System Disease
  • Renal Disease
  • United States
  • Product Initiative

Patients will be randomized (##:##:##) to receive ## mg pacritinib twice daily (BID), ## mg pacritinib once daily (QD) or best available therapy.

  • Pharmaceutical
  • Renal Disease
  • United States
  • World
  • CTI BioPharma Corp.

Genetic Engineering and Biotechnology Heber Biotec S.

  • Clinical Trial
  • Drug Discovery And Development
  • Pharmaceutical
  • Renal Disease
  • World