36 reports

Focus on the development of drugs for new indications such as female dysfunction and genetic obesity is on the rise.

  • Depression
  • Allergan plc
  • Eli Lilly & Co.
  • Pfizer Inc.
  • Takeda Pharmaceutical Company Limited
  • 1.2 TYPES
  • TYPES OF DEPRESSION

There are traces showing that depression runs in families, suggesting a genetic link.

  • Depression
  • World
  • AstraZeneca PLC
  • Lundbeck Inc.
  • Pfizer Inc.

This may be related to genetic predisposition, chronic stress, or illness, certain medications etc.

  • Depression
  • World
  • Market Size
  • Novartis AG
  • Pfizer Inc.
  • Executive Summary
  • 7MM, 12-MONTH TOTAL PREVALENT CASES OF MDD,

Little is known about the etiology of MDD; however, research suggests that there may be combinations of genetic, biological, environmental, and psychological factors that potentially increase the risk of MDD (Mayo Clinic, 2015; MedlinePlus, 2015; National Institute of Mental Health, 2016).

  • Depression
  • Japan
  • United States
  • World
  • Forecast
  • Changes in lifestyle
  • 07. Disorder Overview

Major depressive disorder is mostly caused by psychological, biological, genetic, and social factors.

  • Depression
  • Actavis plc
  • Bristol-Myers Squibb Company
  • Eli Lilly & Co.
  • GlaxoSmithKline plc
  • 3.1 ETIOLOGY AND PATHOPHYSIOLOGY
  • 4.1 DISEASE BACKGROUND

Saying a patient with this profile or genetic makeup, he will benefit from a drug type A, B, or C.

  • Depression
  • Alkermes plc
  • Allergan plc
  • Lundbeck Inc.
  • Otsuka Pharmaceutical Co., Ltd.

The major causes of urine incontinence among women include multiple childbirth, menopause, overweight, genetic weakness, damaged nerves in the bladder, weak bladder muscles, blockage of urethra, tumors, and mental confusion associated with dementia or arthritis.

  • Depression
  • World
  • Boston Scientific Corporation
  • Cyberonics, Inc.
  • EnteroMedics Inc.
  • 07.1 TYPES OF DEPRESSION
  • 11. Market Growth Drivers

Major depressive disorder is mostly caused by psychological, biological, genetic, and social factors.

  • Depression
  • United States
  • Actavis plc
  • Eli Lilly & Co.
  • GlaxoSmithKline plc
  • Depression
  • Pharmaceutical
  • United States
  • Company
  • RespireRx Pharmaceuticals Inc.

We believe SAGE-## will be the first of several product candidates derived from our platform for the treatment of orphan and genetic seizure disorders.

  • Depression
  • United States
  • Company
  • Company Operations
  • SAGE Therapeutics
  • Aug 02, 2017: 23andMe Enrolling For First-of-its-Kind Study on Major Depressive and Bipolar Disorders
  • Aug 02, 2017: 23andMe Enrolling For First-of-its-Kind Study on Major Depressive and Bipolar Disorders

The company offers raw genetic data and ancestry-related genetic reports.

  • Depression
  • Pharmaceutical
  • Therapy
  • United States
  • Lundbeck Inc.

Report covers products from therapy areas Central Nervous System, Cardiovascular and Genetic Disorders which include indications Psychiatric Disorders, Bipolar Disorder (Manic Depression), Major Depressive Disorder, Schizophrenia, Attention Deficit Hyperactivity Disorder (ADHD), Autism, Anx

  • Depression
  • Therapy
  • United States
  • World
  • Product Initiative
  • Metabotropic Glutamate Receptor 2 (GPRC1B or MGLUR2 or GRM2) - Product Development Milestones

In study HBBM, pomaglumetad methionil did not separate from placebo in the primary efficacy endpoint in either the overall or predefined genetic subpopulation at the two doses investigated.

  • Depression
  • Psychotic Disorder
  • World
  • Product Initiative
  • Addex Therapeutics Ltd
  • Featured News & Press Releases

In study HBBM, pomaglumetad methionil did not separate from placebo in the primary efficacy endpoint in either the overall or predefined genetic subpopulation at the two doses investigated.

  • Depression
  • Psychotic Disorder
  • World
  • Product Initiative
  • Addex Therapeutics Ltd
  • R&D Progress
  • R&D Progress

He was also formerly associate medical director of discovery research at Shire Human Genetic Therapies.

  • Depression
  • Mental Health
  • Pharmaceutical
  • Therapy
  • Anavex Life Sciences Corp.

Report covers products from therapy areas Central Nervous System, Cardiovascular, Gastrointestinal and Genetic Disorders which include indications Psychiatric Disorders, Bipolar Disorder (Manic Depression), Schizophrenia, Attention Deficit Hyperactivity Disorder (ADHD), Autism, Major Depres

  • Antipsychotic
  • Depression
  • Therapy
  • United States
  • Product Initiative
  • Metabotropic Glutamate Receptor 2 (GPRC1B or MGLUR2 or GRM2) - Featured News & Press Releases

In study HBBM, pomaglumetad methionil did not separate from placebo in the primary efficacy endpoint in either the overall or predefined genetic subpopulation at the two doses investigated.

  • Depression
  • Pharmaceutical
  • World
  • Product Initiative
  • Addex Therapeutics Ltd

Angelman syndrome is a genetic disease that occurs in ## in ##, ## live births, which leads to mental disabilities and other neurological problems.

  • Depression
  • Pharmaceutical
  • United States
  • Company
  • Neuralstem, Inc.

Celsis will also determine genetic variations in VistaGen' s pluripotent stem cell lines that are important to drug development.

  • Depression
  • United States
  • Company
  • Corporate Finance
  • VistaGen Therapeutics, Inc.

More recently, the group found a genetic basis for those eye movements.

  • Depression
  • Healthcare
  • United States
  • Deals & Alliance
  • GlobalData's company

Rare diseases are often genetic and several million are affected across the world.

  • Depression
  • Therapy
  • United States
  • Company Financials
  • SAGE Therapeutics
  • SMALL MOLECULE TO TARGET SLC6A15 FOR MAJOR DEPRESSIVE DISORDER AND ANXIETY DISORDERS - DRUG PROFILE
  • MIR-135 - DRUG PROFILE

The Company also reported that, in a genetic model of type ## diabetes (db/ db mouse), NSI-## treatment showed significant reversal in all of the same indices of neuropathy.

  • Depression
  • Pharmaceutical
  • United States
  • Product Initiative
  • Allergan plc
  • Depression
  • Therapy
  • United States
  • Product Initiative
  • NeurOp, Inc.

Dr Raye Z Litten, lead author, associate director of the NIAAA Division of Treatment and Recovery Research, said, " Drinking and smoking often co-occur, and given their genetic and neurochemical similarities, it is perhaps unsurprising that a smoking cessation treatment might serve to t

  • Depression
  • OTC
  • Smoking Cessation
  • United States
  • Product Initiative

Dr Raye Z Litten, lead author, associate director of the NIAAA Division of Treatment and Recovery Research, said, " Drinking and smoking often co-occur, and given their genetic and neurochemical similarities, it is perhaps unsurprising that a smoking cessation treatment might serve to t

  • Depression
  • OTC
  • Smoking Cessation
  • United States
  • Product Initiative
  • ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD) - PIPELINE BY P2D BIOSCIENCE
  • DEPRESSION - PIPELINE BY BOEHRINGER INGELHEIM GMBH

Oct ##, 2016: Medgenics Presents New Data Showing Prevalence of Genetic Mutations in Pediatric Populations with Attention Deficit Hyperactivity Disorder Medgenics, Inc.

  • Depression
  • Mental Health
  • United States
  • Product Initiative
  • Pfizer Inc.

THIS INCLUDES DATA FROM MULTIPLE GENETICALLY MODIFIED RODENT MODELS WHERE REDUCTION IN NR##B EXPRESSION IMPAIRS COGNITIVE PERFORMANCE AND INCREASES IN NR##B EXPRESSION IMPROVE COGNITIVE PERFORMANCE.

  • Depression
  • Pathology
  • Therapy
  • United States
  • Product Initiative

Celsis will also determine genetic variations in VistaGen' s pluripotent stem cell lines that are important to drug development.

  • Depression
  • Pharmaceutical
  • United States
  • Company
  • VistaGen Therapeutics, Inc.
  • Depression
  • Mental Health
  • United States
  • Product Initiative
  • Intra-Cellular Therapies, Inc.
  • Introduction

This includes data from multiple genetically modified rodent models where reduction in NR##B expression impairs cognitive performance and increases in NR##B expression improve cognitive performance.

  • Depression
  • Pharmaceutical
  • Therapy
  • United States
  • Product Initiative