About 100 reports

In comparison to the better-established monoclonal antibodies, cell therapies are more difficult to produce safely and consistently.

  • Cell Therapy
  • United States
  • Supply
  • Novartis AG
  • PROVENGE group

Clinical Targets Being Investigated for CAR Cell Therapies in Solid Tumors by Organ Group Gastrointestinal Cancers NGK##D EGFR/ EPCAM GPC## CEACAM## Target ## ## ## ## ## ## ## ## ## AFP GD## HER## IL## MG## MUC## HSP## CLDN## EPCAM PD-L## PROM## PSCA Undisclosed HER##

  • Cell Therapy
  • United States
  • Celgene Corporation
  • Gilead Sciences, Inc.
  • Novartis AG

This substance may be bound to a pharmaceutical compound such as a monoclonal Antibody (mAb) in order to selectively target malignant cells (NCI, 2010).

  • Cell Therapy
  • Market Size
  • Juno Therapeutics Inc.
  • Merck & Co., Inc.
  • Novartis AG

Anti-PD-## antibodies target the protein PD-##, which is expressed by immune cells.

  • Cancer
  • Cell Therapy
  • Medical Biotechnology
  • Therapy
  • United States

Alternatives to ultracentrifugation for exosome isolation include monoclonal antibodybased isolation, which uses monoclonal antibodies specific to exosome surface antigens to isolate the extracellular vesicles from cell culture (Vlassov et al., 2012).

  • Cell Therapy
  • CAP-1002 group
  • Capricor Therapeutics, Inc.
  • Mirna Therapeutics, Inc.
  • ReNeuron Group plc

It is a first in class monoclonal antibody.

  • Cell Therapy
  • Pharmaceutical
  • United States
  • Supply
  • CMC ICOS Biologics, Inc.

Its Bertilimumab is a human monoclonal antibody designed to block the protein eotaxin-## which causes various diseases.

  • Cell Therapy
  • Healthcare
  • Pharmaceutical
  • Demand
  • Lonza Group Ltd

BL-## is a novel monoclonal antibody treatment designed to prevent destruction of insulin-producing beta cells in the pancreas.

  • Biosimilar
  • Biotechnology
  • Cell Therapy
  • China
  • JHL Biotech

About DKN-## DKN-## is a humanized monoclonal antibody that binds to and blocks the activity of the Dickkopf-## (DKK##) protein, a modulator of Wnt/ Beta-catenin signaling, a signaling pathway frequently implicated in tumorigenesis and suppressing the immune system.

  • Cell Therapy
  • Drug Development
  • United States
  • World
  • Product Initiative

Fusion Antibodies plc (Fusion Antibodies), formerly Fusion Antibodies Ltd, is a contract research organization that offers contract services in the production of monoclonal antibodies.

  • Cell Therapy
  • Switzerland
  • United States
  • Company
  • Selexis SA

The prominent features of this report are - ##.

  • Cancer
  • Cell Therapy
  • Clinical Trial
  • World
  • Merck & Co., Inc.

Each unit consists of one share of common stock and one share purchase warrant.

  • Cell Therapy
  • Medical Biotechnology
  • United States
  • Corporate Finance
  • Northwest Biotherapeutics, Inc.

Since CD## binds to the Fc region of tumor-targeted antibodies, FT## can be combined with FDA-approved monoclonal antibody therapy to target a broad spectrum of tumor-associated antigens.

  • Cell Therapy
  • Immunotherapy
  • Therapy
  • United States
  • Fate Therapeutics, Inc.

Hoffmann-La Roche Ltd ## ## ## ## ## ## ## ## Progenics Pharmaceuticals Inc ## ## ## ## ## ## ## ## United Therapeutics Corp ## ## ## ## ## ## ## ## Novartis AG ## ## ## ## ## ## ## ## APEIRON Biologics AG ## ## ## ## ## ## ## ## Pfizer Inc ## ## ## ## ## ## ## ## Y-mAbs Therapeutics Inc ##

  • Cell Therapy
  • Clinical Trial
  • Oncology
  • World
  • Progenics Pharmaceuticals, Inc.

About TECENTRIQ® (atezolizumab) TECENTRIQ is a monoclonal antibody designed to bind with a protein called PD-L##.

  • Cell Therapy
  • Drug Development
  • Lung Cancer
  • Pharmaceutical
  • World

ADCC represents one of the key mechanisms that antibodies utilize to target and kill cancer cells.

  • Cell Therapy
  • Therapy
  • United States
  • Company
  • NantKwest, Inc.

Jude Children' s Research Hospital Inc Berlex Laboratories (Inactive) ## May 1999 ## May 2006 ## ## ## ## A Phase II Trial of R##, a Recombinant Human Monoclonal Antibody to the Insulin-like Growth Factor-## Receptor for the Treatment of Patients with Recurrent or Refra

  • Cell Therapy
  • Clinical Trial
  • Monoclonal Antibody
  • World
  • Product Initiative

The company offers monoclonal antibodies such as IBI##, IBI## and IBI##, among others.

  • Cell Therapy
  • United States
  • Litigation And Patent
  • Supply
  • Aragen Bioscience, Inc.

Fusion Antibodies provides services such as royalty free antibody humanization, antibody chimerization, recombinant protein expression, monoclonal antibody production, stable cell line development and biosimilar development, among others.

  • Cell Therapy
  • Germany
  • Switzerland
  • Supply
  • Celonic AG.

It is a monoclonal antibody.

  • Cell Therapy
  • Pharmaceutical
  • Therapy
  • United States
  • Intrexon Corporation

BL-## is a novel monoclonal antibody treatment designed to prevent destruction of insulin-producing beta cells in the pancreas.

  • Cell Therapy
  • Pharmaceutical
  • Israel
  • United States
  • BioLineRx Ltd.

The company offers monoclonal antibodies such as IBI##, IBI## and IBI##, among others.

  • Cell Therapy
  • Pharmaceutical
  • India
  • Company
  • GVK Biosciences Pvt Ltd

GlobalData Fusion Antibodies Ltd reported one pharmaceuticals & healthcare deal in YTD 2018.

  • Cell Therapy
  • United Kingdom
  • Company
  • Deals & Alliance
  • Chiome Bioscience, Inc.

Ltd., has entered into the license agreement with Becton, Dickinson and Company (BD) in order to develop and commercialize its new monoclonal antibody, BTN## (CD##) antibody which is one of the antibodies generated in the MEDINET' s study of ' Est

  • Cell Therapy
  • Pharmaceutical
  • Japan
  • Corporate Finance
  • Medinet Co., Ltd.

AmplyCell enables its customers to produce more protein out of their own cell lines based on its BOOST technology; and helps optimize, stabilize and increase monoclonal antibody production.

  • Cell Therapy
  • United Kingdom
  • United States
  • Company
  • Horizon Discovery

Promosome provides technology platforms for enhancing the production of recombinant monoclonal antibodies and reengineering of the mRNA primary structure resulting in enhanced protein expression.

  • Cell Therapy
  • Healthcare
  • Pharmaceutical
  • United States
  • GE Healthcare Limited

The prominent features of this report are - ##.

  • Cell Therapy
  • Drug Development
  • Pharmaceutical
  • World
  • Product Initiative

The company offers recombinant proteins, monoclonal antibodies and transfection reagents to life science companies and research laboratories.

  • Cell Therapy
  • Pharmaceutical
  • South Korea
  • M&A
  • Green Cross

In Xintela' s patent family protecting the monoclonal antibody mAb##, the USPTO has also issued a NoA for the follow-up application, that broadens the protection conferred by previously granted patents.

  • Cell Therapy
  • Germany
  • Company
  • Supply
  • CellSeed Inc.

The prominent features of this report are - ##.

  • Cancer
  • Cell Therapy
  • Therapy
  • World
  • Product Initiative